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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Beutenbergia cavernae (strain ATCC BAA-8 / DSM 12333 / NBRC 16432)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei35 – 351SubstrateUniRule annotation
Binding sitei117 – 1171SubstrateUniRule annotation
Binding sitei154 – 1541SubstrateUniRule annotation
Binding sitei204 – 2041ATPUniRule annotation
Binding sitei295 – 2951ATP; via carbonyl oxygenUniRule annotation
Binding sitei326 – 3261ATPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi355 – 3584ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBCAV471853:GI1Z-2201-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:Bcav_2170
OrganismiBeutenbergia cavernae (strain ATCC BAA-8 / DSM 12333 / NBRC 16432)
Taxonomic identifieri471853 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeBeutenbergiaceaeBeutenbergia
ProteomesiUP000007962 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 399399Phosphoglycerate kinasePRO_1000203320Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi471853.Bcav_2170.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni20 – 223Substrate bindingUniRule annotation
Regioni58 – 614Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227108.
KOiK00927.
OMAiDAFGTCH.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C5BV35-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRTIDDLGEL RGKTVLVRSD FNVPLDGTTI TDDGRIRAAL PTLKRLVDAG
60 70 80 90 100
AKVVVTAHLG RPKGAPDPAF SLAPVAQRLG ALLGTPVALA ADVVGPSAHE
110 120 130 140 150
TVAALSDGDV ALLENVRFDP RESSKDDAER LELARAFAEL ADAFVSDGFG
160 170 180 190 200
VVHRKQASVY DVATLLPHAA GDLVLAEVTA LRKATDDPER PYAVVLGGSK
210 220 230 240 250
VSDKLGVIAN LLTKADTLLI GGGMVFTFLA AQGHQVGKSL LEEDQIDTVK
260 270 280 290 300
GYLDQAEQSG VTIVLPTDIV AAEAFAADAP HQVVAADAIP ADSIGLDIGP
310 320 330 340 350
ESGEAFAAVI RGAKTVVWNG PMGVFEFDAF AAGTRAVAQG LTDATAAGAF
360 370 380 390
TIVGGGDSAA AVRSLGFDEA GFSHISTGGG ASLEFLEGKT LPGLAVLED
Length:399
Mass (Da):40,893
Last modified:July 28, 2009 - v1
Checksum:iDB2B47198B06BF77
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001618 Genomic DNA. Translation: ACQ80422.1.
RefSeqiWP_015882662.1. NC_012669.1.
YP_002882184.1. NC_012669.1.

Genome annotation databases

EnsemblBacteriaiACQ80422; ACQ80422; Bcav_2170.
KEGGibcv:Bcav_2170.
PATRICi21094990. VBIBeuCav91323_2206.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001618 Genomic DNA. Translation: ACQ80422.1.
RefSeqiWP_015882662.1. NC_012669.1.
YP_002882184.1. NC_012669.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi471853.Bcav_2170.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACQ80422; ACQ80422; Bcav_2170.
KEGGibcv:Bcav_2170.
PATRICi21094990. VBIBeuCav91323_2206.

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227108.
KOiK00927.
OMAiDAFGTCH.
OrthoDBiEOG64N9Z0.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185.
BioCyciBCAV471853:GI1Z-2201-MONOMER.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-8 / DSM 12333 / NBRC 16432.

Entry informationi

Entry nameiPGK_BEUC1
AccessioniPrimary (citable) accession number: C5BV35
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: May 27, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.