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C5BV35 (PGK_BEUC1) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:Bcav_2170
OrganismBeutenbergia cavernae (strain ATCC BAA-8 / DSM 12333 / NBRC 16432) [Complete proteome] [HAMAP]
Taxonomic identifier471853 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeBeutenbergiaceaeBeutenbergia

Protein attributes

Sequence length399 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 399399Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_1000203320

Regions

Nucleotide binding355 – 3584ATP By similarity
Region20 – 223Substrate binding By similarity
Region58 – 614Substrate binding By similarity

Sites

Binding site351Substrate By similarity
Binding site1171Substrate By similarity
Binding site1541Substrate By similarity
Binding site2041ATP By similarity
Binding site2951ATP; via carbonyl oxygen By similarity
Binding site3261ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
C5BV35 [UniParc].

Last modified July 28, 2009. Version 1.
Checksum: DB2B47198B06BF77

FASTA39940,893
        10         20         30         40         50         60 
MRTIDDLGEL RGKTVLVRSD FNVPLDGTTI TDDGRIRAAL PTLKRLVDAG AKVVVTAHLG 

        70         80         90        100        110        120 
RPKGAPDPAF SLAPVAQRLG ALLGTPVALA ADVVGPSAHE TVAALSDGDV ALLENVRFDP 

       130        140        150        160        170        180 
RESSKDDAER LELARAFAEL ADAFVSDGFG VVHRKQASVY DVATLLPHAA GDLVLAEVTA 

       190        200        210        220        230        240 
LRKATDDPER PYAVVLGGSK VSDKLGVIAN LLTKADTLLI GGGMVFTFLA AQGHQVGKSL 

       250        260        270        280        290        300 
LEEDQIDTVK GYLDQAEQSG VTIVLPTDIV AAEAFAADAP HQVVAADAIP ADSIGLDIGP 

       310        320        330        340        350        360 
ESGEAFAAVI RGAKTVVWNG PMGVFEFDAF AAGTRAVAQG LTDATAAGAF TIVGGGDSAA 

       370        380        390 
AVRSLGFDEA GFSHISTGGG ASLEFLEGKT LPGLAVLED 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001618 Genomic DNA. Translation: ACQ80422.1.
RefSeqYP_002882184.1. NC_012669.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING471853.Bcav_2170.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACQ80422; ACQ80422; Bcav_2170.
GeneID7859531.
KEGGbcv:Bcav_2170.
PATRIC21094990. VBIBeuCav91323_2206.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227108.
KOK00927.
OMADMIFDIG.
OrthoDBEOG64N9Z0.
ProtClustDBCLSK2547888.

Enzyme and pathway databases

BioCycBCAV471853:GI1Z-2201-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_BEUC1
AccessionPrimary (citable) accession number: C5BV35
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: February 19, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways