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C5BRP6 (UPPP_TERTT) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:TERTU_1199
OrganismTeredinibacter turnerae (strain ATCC 39867 / T7901) [Complete proteome] [HAMAP]
Taxonomic identifier377629 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesAlteromonadales genera incertae sedisTeredinibacter

Protein attributes

Sequence length264 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 264264Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_1000213161

Regions

Transmembrane1 – 2121Helical; Potential
Transmembrane39 – 5921Helical; Potential
Transmembrane87 – 10721Helical; Potential
Transmembrane111 – 13121Helical; Potential
Transmembrane144 – 16421Helical; Potential
Transmembrane187 – 20721Helical; Potential
Transmembrane208 – 22821Helical; Potential
Transmembrane244 – 26421Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
C5BRP6 [UniParc].

Last modified July 28, 2009. Version 1.
Checksum: BD3DECC4AD72921F

FASTA26428,271
        10         20         30         40         50         60 
MDLIHVVVLA LIQGITEFLP ISSSAHLILP KEILGWPDQG LAFDVAVHVG TLTAVAVYFR 

        70         80         90        100        110        120 
NDIGKIIIGW LSSVTGRGTD ESGRLGWYLI AATIPAALFG LIFDDLIETH LRSTDVIATT 

       130        140        150        160        170        180 
TLVFGVLLWV ADRKPAETKQ LRDIALSTAM IIGLAQAVAL IPGTSRSGIT ITAALFLGLC 

       190        200        210        220        230        240 
RTDAARFSFL LSIPVIVLSG GYKGLQLVLS AAAVDWLAIG LGIALSAVSA YICIHYFLNF 

       250        260 
INRIGMLPFV IYRLLLGVLL FIAV 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001614 Genomic DNA. Translation: ACR13919.1.
RefSeqYP_003072776.1. NC_012997.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING377629.TERTU_1199.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACR13919; ACR13919; TERTU_1199.
GeneID8213997.
KEGGttu:TERTU_1199.
PATRIC23869571. VBITerTur118718_1130.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMAMGASKRS.
OrthoDBEOG6QP13M.
ProtClustDBPRK00281.

Enzyme and pathway databases

BioCycTTUR377629:GHSU-1093-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_TERTT
AccessionPrimary (citable) accession number: C5BRP6
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: February 19, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families