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Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene

TERTU_1960

Organism
Teredinibacter turnerae (strain ATCC 39867 / T7901)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Cofactori

Mg2+UniRule annotation, Mn2+UniRule annotationNote: Binds 1 Mg(2+) or Mn2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei147 – 1471SubstrateUniRule annotation
Sitei257 – 2571Critical for catalysisUniRule annotation
Metal bindingi352 – 3521Magnesium or manganeseUniRule annotation
Sitei422 – 4221Critical for catalysisUniRule annotation
Binding sitei549 – 5491SubstrateUniRule annotation
Metal bindingi550 – 5501Magnesium or manganeseUniRule annotation
Metal bindingi554 – 5541Magnesium or manganeseUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciTTUR377629:GHSU-1775-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
Gene namesi
Ordered Locus Names:TERTU_1960Imported
OrganismiTeredinibacter turnerae (strain ATCC 39867 / T7901)Imported
Taxonomic identifieri377629 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesAlteromonadales genera incertae sedisTeredinibacter
ProteomesiUP000009080 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi377629.TERTU_1960.

Structurei

3D structure databases

ProteinModelPortaliC5BIJ2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni134 – 1418Substrate bindingUniRule annotation

Phylogenomic databases

eggNOGiCOG2838.
HOGENOMiHOG000240860.
KOiK00031.
OMAiRDSGKMW.
OrthoDBiEOG6DVJPP.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

C5BIJ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSDKPAIIY TETDEAPALA TYSLLPIVQA FAKAAGISVE TKDISLSGRV
60 70 80 90 100
IANFSDYLTA DQQQEDALAL LGELATKPEA NIIKLPNISA SVPQLQATIK
110 120 130 140 150
ELQAKGYKLP DYPADPSTEE EKSVKARYDK IKGSAVNPVL REGNSDRRAP
160 170 180 190 200
ASVKQYARKN PHSMGAWESS SKSHVSAMTD GDFYGSEQSV TVDSATTVSI
210 220 230 240 250
QLVTDAGETL VLKDSLPLQA SEIIDSSVLS KTALTAFLAE QIEDAKAQDV
260 270 280 290 300
LFSLHMKATM MKVSDPIIFG HAVKVFYNSV FDKHAATFAE LGVDANNGVG
310 320 330 340 350
DVYAKIAALP DDKRAEIEAD FAALYAERPP LAMVNSDKGI TNLHVPSDII
360 370 380 390 400
IDASMPAMIR ASGQMWGPDG KQKDTKAVIP DRCYAGVYQT TIEFCKQHGA
410 420 430 440 450
FDPTTMGTVP NVGLMAQKAE EYGSHDKTFE ISAAGKVQVV DADGTVLMEH
460 470 480 490 500
SVEPGDIFRA CQVKDAPVQD WVKLAVTRAR LSATPAVFWL DEARAHDAQL
510 520 530 540 550
IEKVKTYLQD HDTDGLDIRI LAPVEATQFS LERMKNGEDT ISVTGNVLRD
560 570 580 590 600
YLTDLFPILE LGTSAKMLSV VPLMNGGGLF ETGAGGSAPK HVEQFVQENH
610 620 630 640 650
LRWDSLGEFL ALAASFEHYG VVHSSEQAKV LADTLDKATA KFLDNNKSPS
660 670 680 690 700
RKVGELDNRG SHFYLALYWA QELAAQNADT ALQSQFTTVA EAMSAAEQAI
710 720 730 740
VDELNSAQGQ AVEINGYYKP EPALVSAAMR ASKTLNAIVD AI
Length:742
Mass (Da):80,088
Last modified:July 28, 2009 - v1
Checksum:i90FAE076B406803C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001614 Genomic DNA. Translation: ACR14526.1.
RefSeqiWP_015820640.1. NC_012997.1.

Genome annotation databases

EnsemblBacteriaiACR14526; ACR14526; TERTU_1960.
KEGGittu:TERTU_1960.
PATRICi23870973. VBITerTur118718_1820.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001614 Genomic DNA. Translation: ACR14526.1.
RefSeqiWP_015820640.1. NC_012997.1.

3D structure databases

ProteinModelPortaliC5BIJ2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi377629.TERTU_1960.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACR14526; ACR14526; TERTU_1960.
KEGGittu:TERTU_1960.
PATRICi23870973. VBITerTur118718_1820.

Phylogenomic databases

eggNOGiCOG2838.
HOGENOMiHOG000240860.
KOiK00031.
OMAiRDSGKMW.
OrthoDBiEOG6DVJPP.

Enzyme and pathway databases

BioCyciTTUR377629:GHSU-1775-MONOMER.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 39867 / T7901Imported.

Entry informationi

Entry nameiC5BIJ2_TERTT
AccessioniPrimary (citable) accession number: C5BIJ2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: July 22, 2015
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.