C5BIJ2 (C5BIJ2_TERTT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Isocitrate dehydrogenase, NADP-dependent EMBL ACR14526.1
EC=1.1.1.42 EMBL ACR14526.1

Gene names

Ordered Locus Names:

TERTU_1960

Organism

Teredinibacter turnerae (strain ATCC 39867 / T7901) [Complete proteome] [HAMAP] EMBL ACR14526.1

Taxonomic identifier

377629 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Alteromonadales genera incertae sedis › Teredinibacter › Teredinibacter turnerae

Protein attributes

Sequence length	742 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. PIRSR PIRSR009407-3

Ontologies

Keywords
Ligand	Magnesium PIRSR PIRSR009407-3 Metal-binding PIRSR PIRSR009407-3
Molecular function	Oxidoreductase EMBL ACR14526.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	isocitrate dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Region	134 – 141	8	Substrate binding By similarity PIRSR PIRSR009407-2
Sites
	Metal binding	352	1	Magnesium or manganese By similarity PIRSR PIRSR009407-3
	Metal binding	550	1	Magnesium or manganese By similarity PIRSR PIRSR009407-3
	Metal binding	554	1	Magnesium or manganese By similarity PIRSR PIRSR009407-3
	Binding site	147	1	Substrate By similarity PIRSR PIRSR009407-2
	Binding site	549	1	Substrate By similarity PIRSR PIRSR009407-2
	Site	257	1	Critical for catalysis By similarity PIRSR PIRSR009407-1
	Site	422	1	Critical for catalysis By similarity PIRSR PIRSR009407-1

Sequences

	Sequence		Length	Mass (Da)
	C5BIJ2 [UniParc]. Last modified July 28, 2009. Version 1. Checksum: 90FAE076B406803C	FASTA	742	80,088
	10 20 30 40 50 60 MSSDKPAIIY TETDEAPALA TYSLLPIVQA FAKAAGISVE TKDISLSGRV IANFSDYLTA 70 80 90 100 110 120 DQQQEDALAL LGELATKPEA NIIKLPNISA SVPQLQATIK ELQAKGYKLP DYPADPSTEE 130 140 150 160 170 180 EKSVKARYDK IKGSAVNPVL REGNSDRRAP ASVKQYARKN PHSMGAWESS SKSHVSAMTD 190 200 210 220 230 240 GDFYGSEQSV TVDSATTVSI QLVTDAGETL VLKDSLPLQA SEIIDSSVLS KTALTAFLAE 250 260 270 280 290 300 QIEDAKAQDV LFSLHMKATM MKVSDPIIFG HAVKVFYNSV FDKHAATFAE LGVDANNGVG 310 320 330 340 350 360 DVYAKIAALP DDKRAEIEAD FAALYAERPP LAMVNSDKGI TNLHVPSDII IDASMPAMIR 370 380 390 400 410 420 ASGQMWGPDG KQKDTKAVIP DRCYAGVYQT TIEFCKQHGA FDPTTMGTVP NVGLMAQKAE 430 440 450 460 470 480 EYGSHDKTFE ISAAGKVQVV DADGTVLMEH SVEPGDIFRA CQVKDAPVQD WVKLAVTRAR 490 500 510 520 530 540 LSATPAVFWL DEARAHDAQL IEKVKTYLQD HDTDGLDIRI LAPVEATQFS LERMKNGEDT 550 560 570 580 590 600 ISVTGNVLRD YLTDLFPILE LGTSAKMLSV VPLMNGGGLF ETGAGGSAPK HVEQFVQENH 610 620 630 640 650 660 LRWDSLGEFL ALAASFEHYG VVHSSEQAKV LADTLDKATA KFLDNNKSPS RKVGELDNRG 670 680 690 700 710 720 SHFYLALYWA QELAAQNADT ALQSQFTTVA EAMSAAEQAI VDELNSAQGQ AVEINGYYKP 730 740 EPALVSAAMR ASKTLNAIVD AI

References

[1]

"The complete genome of Teredinibacter turnerae T7901: an intracellular endosymbiont of marine wood-boring bivalves (shipworms)." Yang J.C., Madupu R., Durkin A.S., Ekborg N.A., Pedamallu C.S., Hostetler J.B., Radune D., Toms B.S., Henrissat B., Coutinho P.M., Schwarz S., Field L., Trindade-Silva A.E., Soares C.A.G., Elshahawi S., Hanora A., Schmidt E.W., Haygood M.G. , Posfai J., Benner J., Madinger C., Nove J., Anton B., Chaudhary K., Foster J., Holman A., Kumar S., Lessard P.A., Luyten Y.A., Slatko B., Wood N., Wu B., Teplitski M., Mougous J.D., Ward N., Eisen J.A., Badger J.H., Distel D.L. PLoS ONE 4:E6085-E6085(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 39867 / T7901.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001614 Genomic DNA. Translation: ACR14526.1.
RefSeq	YP_003073446.1. NC_012997.1.
3D structure databases
ProteinModelPortal	C5BIJ2.
ModBase	Search...
Protein-protein interaction databases
STRING	377629.TERTU_1960.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACR14526; ACR14526; TERTU_1960.
GeneID	8211505.
KEGG	ttu:TERTU_1960.
PATRIC	23870973. VBITerTur118718_1820.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2838.
HOGENOM	HOG000240860.
KO	K00031.
OMA	FRMCQTK.
ProtClustDB	CLSK867411.
Family and domain databases
Gene3D	3.40.718.10. 3 hits.
InterPro	IPR004436. Isocitrate_DH_NADP_mono. IPR024084. IsoPropMal-DH-like_dom. [Graphical view]
Pfam	PF03971. IDH. 1 hit. [Graphical view]
PIRSF	PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMs	TIGR00178. monomer_idh. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C5BIJ2_TERTT

Accession

Primary (citable) accession number: C5BIJ2

Entry history

Integrated into UniProtKB/TrEMBL:	July 28, 2009
Last sequence update:	July 28, 2009
Last modified:	May 1, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)