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Protein

Uronate isomerase

Gene

uxaC

Organism
Edwardsiella ictaluri (strain 93-146)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:NT01EI_0502
OrganismiEdwardsiella ictaluri (strain 93-146)
Taxonomic identifieri634503 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesHafniaceaeEdwardsiella
Proteomesi
  • UP000001485 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002125171 – 469Uronate isomeraseAdd BLAST469

Proteomic databases

PRIDEiC5BH54.

Interactioni

Protein-protein interaction databases

STRINGi634503.NT01EI_0502.

Structurei

3D structure databases

ProteinModelPortaliC5BH54.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiREMTTET.
OrthoDBiPOG091H07GL.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

C5BH54-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPFLTEDFL LDTEFARRLY HDYAEEQPIF DYHCHLPPEQ IAENYRFKNL
60 70 80 90 100
YDIWLKGDHY KWRAMRTNGV AECFCTGEAS DREKFQAWAE TVPHTIGNPL
110 120 130 140 150
YHWTHLELRR PFGITDTLLS ATTAEDIWTR CNRMLAEDSF TARGIMGQMN
160 170 180 190 200
VKMVGTTDDP IDDLRHHRTI AADSSFTTKV LPSWRPDKAF NIEAALFSDY
210 220 230 240 250
IVKLGAVADV DITRFADLCQ ALKVRMDHFA AHGCKVSDHA LDVVVYGEAD
260 270 280 290 300
DATLDGILAR RLSGGTPGEI EVAQFKTAVL LFLGCEYRRR GWVQQYHIGA
310 320 330 340 350
LRNNNTPMFE RLGPDIGFDS INDAPVAQPL SRLLDAQSRN GGLTKTILYC
360 370 380 390 400
LNPRDNEVLG TMIGNFQGEG MPGKMQFGSG WWFNDQKDGM QRQMTQLAQL
410 420 430 440 450
GLLSRFVGML TDSRSFLSYT RHEYFRRILC QMIGRWVAQG EAPADIALLG
460
SMVKNICFDN AKSYFAIEL
Length:469
Mass (Da):53,292
Last modified:July 28, 2009 - v1
Checksum:iEBB29A3EF91514D3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001600 Genomic DNA. Translation: ACR67737.1.
RefSeqiWP_015869938.1. NC_012779.2.

Genome annotation databases

EnsemblBacteriaiACR67737; ACR67737; NT01EI_0502.
GeneIDi7961529.
KEGGieic:NT01EI_0502.
PATRICi21834251. VBIEdwIct114273_0455.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001600 Genomic DNA. Translation: ACR67737.1.
RefSeqiWP_015869938.1. NC_012779.2.

3D structure databases

ProteinModelPortaliC5BH54.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi634503.NT01EI_0502.

Proteomic databases

PRIDEiC5BH54.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACR67737; ACR67737; NT01EI_0502.
GeneIDi7961529.
KEGGieic:NT01EI_0502.
PATRICi21834251. VBIEdwIct114273_0455.

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000224075.
KOiK01812.
OMAiREMTTET.
OrthoDBiPOG091H07GL.

Enzyme and pathway databases

UniPathwayiUPA00246.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUXAC_EDWI9
AccessioniPrimary (citable) accession number: C5BH54
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: November 2, 2016
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.