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Protein

Cobalt-precorrin-5B C(1)-methyltransferase

Gene

cbiD

Organism
Edwardsiella ictaluri (strain 93-146)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.UniRule annotation

Catalytic activityi

Cobalt-precorrin-5B + S-adenosyl-L-methionine = cobalt-precorrin-6A + S-adenosyl-L-homocysteine.UniRule annotation

Pathwayi: adenosylcobalamin biosynthesis

This protein is involved in step 6 of the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route).UniRule annotation
Proteins known to be involved in the 10 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. no protein annotated in this organism
  3. no protein annotated in this organism
  4. no protein annotated in this organism
  5. no protein annotated in this organism
  6. Cobalt-precorrin-5B C(1)-methyltransferase (cbiD)
  7. no protein annotated in this organism
  8. no protein annotated in this organism
  9. no protein annotated in this organism
  10. Cobyrinate a,c-diamide synthase (cbiA)
This subpathway is part of the pathway adenosylcobalamin biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route), the pathway adenosylcobalamin biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processCobalamin biosynthesis
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciEICT634503:G1GVC-1993-MONOMER
UniPathwayiUPA00148; UER00227

Names & Taxonomyi

Protein namesi
Recommended name:
Cobalt-precorrin-5B C(1)-methyltransferaseUniRule annotation (EC:2.1.1.195UniRule annotation)
Alternative name(s):
Cobalt-precorrin-6A synthaseUniRule annotation
Gene namesi
Name:cbiDUniRule annotation
Ordered Locus Names:NT01EI_2190
OrganismiEdwardsiella ictaluri (strain 93-146)
Taxonomic identifieri634503 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesHafniaceaeEdwardsiella
Proteomesi
  • UP000001485 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002129361 – 379Cobalt-precorrin-5B C(1)-methyltransferaseAdd BLAST379

Proteomic databases

PRIDEiC5BFT8

Interactioni

Protein-protein interaction databases

STRINGi634503.NT01EI_2190

Structurei

3D structure databases

SMRiC5BFT8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CbiD family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105EE8 Bacteria
COG1903 LUCA
HOGENOMiHOG000009126
KOiK02188
OMAiGGIFHTH
OrthoDBiPOG091H02QJ

Family and domain databases

Gene3Di3.30.2110.10, 1 hit
HAMAPiMF_00787 CbiD, 1 hit
InterProiView protein in InterPro
IPR002748 CbiD
IPR036074 CbiD_sf
PANTHERiPTHR35863 PTHR35863, 1 hit
PfamiView protein in Pfam
PF01888 CbiD, 1 hit
PIRSFiPIRSF026782 CbiD, 1 hit
SUPFAMiSSF111342 SSF111342, 1 hit
TIGRFAMsiTIGR00312 cbiD, 1 hit

Sequencei

Sequence statusi: Complete.

C5BFT8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDRAFDTPV WHHGKALRKG YTTGSCATAA AKVAALMALR QQPIHQIAIV
60 70 80 90 100
TPSGVTLNLS VESPHIEGEQ AIAAIRKDGG DDVDATHGML IFARVTLNDS
110 120 130 140 150
GAISLSGGEG IGTVTRKGIG LPIGSAAINR TPRHTIESAV REAIGPTRGA
160 170 180 190 200
AVEIFAPEGV ARAQKTYNAR LGILGGISII GTTGIVTPMS EESWKRSLAL
210 220 230 240 250
TLEMKRAAGM TRVVLVPGNH GERFVREQMG IAADAVVTMS NFVGYMVEEA
260 270 280 290 300
VRLGFRQIVL VGHPGKLIKV AAGIFHTHSH MADARMETLV AHLALLGAPL
310 320 330 340 350
ALLTRVRDCD TTEAAMEHID AYGFQSLYDH LAARICQRVI ERLRFTQNLP
360 370
ICDAILFSFD NRTLGSNRPV AAIVEDLRC
Length:379
Mass (Da):40,550
Last modified:July 28, 2009 - v1
Checksum:iCD0436662E9631F1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001600 Genomic DNA Translation: ACR69365.1
RefSeqiWP_015871491.1, NC_012779.2

Genome annotation databases

EnsemblBacteriaiACR69365; ACR69365; NT01EI_2190
GeneIDi7961623
KEGGieic:NT01EI_2190
PATRICifig|634503.3.peg.1955

Similar proteinsi

Entry informationi

Entry nameiCBID_EDWI9
AccessioniPrimary (citable) accession number: C5BFT8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: May 23, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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