Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Adenine deaminase

Gene

ade

Organism
Edwardsiella ictaluri (strain 93-146)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Manganese

Enzyme and pathway databases

BioCyciEICT634503:GCMY-3900-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminaseUniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
AdenaseUniRule annotation
Short name:
Adenine aminaseUniRule annotation
Gene namesi
Name:adeUniRule annotation
Ordered Locus Names:NT01EI_3924
OrganismiEdwardsiella ictaluri (strain 93-146)
Taxonomic identifieri634503 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEdwardsiella
Proteomesi
  • UP000001485 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 591591Adenine deaminasePRO_1000215361Add
BLAST

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi634503.NT01EI_3924.

Structurei

3D structure databases

ProteinModelPortaliC5BF52.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the adenine deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiCTDDKHL.
OrthoDBiEOG622PNM.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.

Sequencei

Sequence statusi: Complete.

C5BF52-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDIHHKHTQ SVSRSDMLRL LAVSRGDQPA DLIIDNVFLL DLINGGTLPG
60 70 80 90 100
PILISGDSIA GVGPAYAGTA ALERIDAGGA IAVPGFIDAH LHIESSMMTP
110 120 130 140 150
IAFESVTLPL GVTTIVCDPH EIVNVMGEKG LTWFLRCAEG AQQNQFIQIS
160 170 180 190 200
SCVPALAGTD INGAEFPLTA MLPYREHPHV LGLAEMMNFP GVIAGDEPTL
210 220 230 240 250
DKLDAFRHLT LDGHSPMLSG KALNAYLAAG VENCHETLAL EEGREKLALG
260 270 280 290 300
MALMIREGSA ARNLDTLAPL ISEFNSPQCM LCTDDRNPWE IAHEGHIDAL
310 320 330 340 350
IRRLIQRHHI APHVAYRVAS WSAARHFGLK RLGLIAPGKK ADIVLLDNLE
360 370 380 390 400
QVAIRQVFAG GKAIDAQQLL RSAAMRQLAS CPPQHNTLRR APLSAEDLTL
410 420 430 440 450
PLTQDADYRA IQLIPNELIT PARTVRWLGD GFDTPDVCRI AVMERYGQQR
460 470 480 490 500
VPALGLLHNS GLSKGALAAT VSHDSHNIVV IGHHPAEMAL AVNQLIDDGG
510 520 530 540 550
GLCVVADGQV VVHLPLPIAG LMSSRSAAEI ADIIDALKQA CRNCGMTLNE
560 570 580 590
PFIQMAFLSL PVIPSLKLTS LGLYDVDHFR FTEVRIPEES A
Length:591
Mass (Da):63,675
Last modified:July 28, 2009 - v1
Checksum:iE114366A4EB333FB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001600 Genomic DNA. Translation: ACR71035.1.
RefSeqiWP_015873062.1. NC_012779.2.

Genome annotation databases

EnsemblBacteriaiACR71035; ACR71035; NT01EI_3924.
GeneIDi7961490.
KEGGieic:NT01EI_3924.
PATRICi21840523. VBIEdwIct114273_3495.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001600 Genomic DNA. Translation: ACR71035.1.
RefSeqiWP_015873062.1. NC_012779.2.

3D structure databases

ProteinModelPortaliC5BF52.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi634503.NT01EI_3924.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACR71035; ACR71035; NT01EI_3924.
GeneIDi7961490.
KEGGieic:NT01EI_3924.
PATRICi21840523. VBIEdwIct114273_3495.

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiCTDDKHL.
OrthoDBiEOG622PNM.

Enzyme and pathway databases

BioCyciEICT634503:GCMY-3900-MONOMER.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Edwardsiella ictaluri 93-146."
    Williams M.L., Gillaspy A.F., Dyer D.W., Thune R.L., Waldbieser G.C., Schuster S.C., Gipson J., Zaitshik J., Landry C., Lawrence M.L.
    Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 93-146.

Entry informationi

Entry nameiADEC_EDWI9
AccessioniPrimary (citable) accession number: C5BF52
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: November 11, 2015
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.