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C5BD56 (PNCB_EDWI9) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:NT01EI_1361
OrganismEdwardsiella ictaluri (strain 93-146) [Complete proteome] [HAMAP]
Taxonomic identifier634503 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEdwardsiella

Protein attributes

Sequence length401 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 401401Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_1000212084

Sequences

Sequence LengthMass (Da)Tools
C5BD56 [UniParc].

Last modified July 28, 2009. Version 1.
Checksum: 6CC3CEA4DB8DE6DD

FASTA40145,538
        10         20         30         40         50         60 
MTQDVSPIIT SLLDTDAYKL HMQQAVYHRY RNVSVAAEFR CRGDELLGEY AGEIANQVNL 

        70         80         90        100        110        120 
MGQLALTQDE YDYLAALPFF QRDYLDWLRT LRLDPRRVAI SNDRGRLNIR ISGPWREVIL 

       130        140        150        160        170        180 
WEVPLLAVIS EVVHRHRSPH ITPEVAAAQL QRRLSEFRHL SADVDLRGFH LIDFGTRRRF 

       190        200        210        220        230        240 
SRAVHQAILT TLKSEFPYLS GTSNYLFAKQ MALTPLGTQA HEWFQAHQQI CPVLANSQRA 

       250        260        270        280        290        300 
ALQSWLDEYP DQLGIALTDC ITMDAFLRDF GSQFAGHYQG LRHDSGDPIA WGEKAIAHYE 

       310        320        330        340        350        360 
QLGLDPQDKM LVFSDNLDLP KALALYRHFH HRINLSFGIG TRLTCDLPGV RPLNIVIKLV 

       370        380        390        400 
ECNGKPVAKL SDSPGKTICQ DAAFVKALRK AFDLPLVKRA S 

« Hide

References

[1]"Complete genome sequence of Edwardsiella ictaluri 93-146."
Williams M.L., Gillaspy A.F., Dyer D.W., Thune R.L., Waldbieser G.C., Schuster S.C., Gipson J., Zaitshik J., Landry C., Lawrence M.L.
Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 93-146.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001600 Genomic DNA. Translation: ACR68551.1.
RefSeqYP_002932786.1. NC_012779.2.

3D structure databases

ProteinModelPortalC5BD56.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING634503.NT01EI_1361.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACR68551; ACR68551; NT01EI_1361.
GeneID7960444.
KEGGeic:NT01EI_1361.
PATRIC21835848. VBIEdwIct114273_1224.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
KOK00763.
OMAQAVFHRY.
OrthoDBEOG6X10XB.

Enzyme and pathway databases

BioCycEICT634503:GCMY-1344-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_EDWI9
AccessionPrimary (citable) accession number: C5BD56
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: May 14, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways