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C5BD56

- PNCB_EDWI9

UniProt

C5BD56 - PNCB_EDWI9

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Protein
Nicotinate phosphoribosyltransferase
Gene
pncB, NT01EI_1361
Organism
Edwardsiella ictaluri (strain 93-146)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity.UniRule annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ligase activity Source: UniProtKB-KW
  2. nicotinate phosphoribosyltransferase activity Source: InterPro
  3. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro

GO - Biological processi

  1. NAD biosynthetic process Source: UniProtKB-UniPathway
  2. nicotinate nucleotide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase, Transferase

Keywords - Biological processi

Pyridine nucleotide biosynthesis

Enzyme and pathway databases

BioCyciEICT634503:GCMY-1344-MONOMER.
UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferase (EC:6.3.4.21)
Short name:
NAPRTase
Gene namesi
Name:pncB
Ordered Locus Names:NT01EI_1361
OrganismiEdwardsiella ictaluri (strain 93-146)
Taxonomic identifieri634503 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEdwardsiella
ProteomesiUP000001485: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 401401Nicotinate phosphoribosyltransferaseUniRule annotation
PRO_1000212084Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi634503.NT01EI_1361.

Structurei

3D structure databases

ProteinModelPortaliC5BD56.

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.

Phylogenomic databases

eggNOGiCOG1488.
HOGENOMiHOG000284928.
KOiK00763.
OMAiQAVFHRY.
OrthoDBiEOG6X10XB.

Family and domain databases

HAMAPiMF_00570. NAPRTase.
InterProiIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

C5BD56-1 [UniParc]FASTAAdd to Basket

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MTQDVSPIIT SLLDTDAYKL HMQQAVYHRY RNVSVAAEFR CRGDELLGEY    50
AGEIANQVNL MGQLALTQDE YDYLAALPFF QRDYLDWLRT LRLDPRRVAI 100
SNDRGRLNIR ISGPWREVIL WEVPLLAVIS EVVHRHRSPH ITPEVAAAQL 150
QRRLSEFRHL SADVDLRGFH LIDFGTRRRF SRAVHQAILT TLKSEFPYLS 200
GTSNYLFAKQ MALTPLGTQA HEWFQAHQQI CPVLANSQRA ALQSWLDEYP 250
DQLGIALTDC ITMDAFLRDF GSQFAGHYQG LRHDSGDPIA WGEKAIAHYE 300
QLGLDPQDKM LVFSDNLDLP KALALYRHFH HRINLSFGIG TRLTCDLPGV 350
RPLNIVIKLV ECNGKPVAKL SDSPGKTICQ DAAFVKALRK AFDLPLVKRA 400
S 401
Length:401
Mass (Da):45,538
Last modified:July 28, 2009 - v1
Checksum:i6CC3CEA4DB8DE6DD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001600 Genomic DNA. Translation: ACR68551.1.
RefSeqiYP_002932786.1. NC_012779.2.

Genome annotation databases

EnsemblBacteriaiACR68551; ACR68551; NT01EI_1361.
GeneIDi7960444.
KEGGieic:NT01EI_1361.
PATRICi21835848. VBIEdwIct114273_1224.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001600 Genomic DNA. Translation: ACR68551.1 .
RefSeqi YP_002932786.1. NC_012779.2.

3D structure databases

ProteinModelPortali C5BD56.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 634503.NT01EI_1361.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACR68551 ; ACR68551 ; NT01EI_1361 .
GeneIDi 7960444.
KEGGi eic:NT01EI_1361.
PATRICi 21835848. VBIEdwIct114273_1224.

Phylogenomic databases

eggNOGi COG1488.
HOGENOMi HOG000284928.
KOi K00763.
OMAi QAVFHRY.
OrthoDBi EOG6X10XB.

Enzyme and pathway databases

UniPathwayi UPA00253 ; UER00457 .
BioCyci EICT634503:GCMY-1344-MONOMER.

Family and domain databases

HAMAPi MF_00570. NAPRTase.
InterProi IPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view ]
PANTHERi PTHR11098. PTHR11098. 1 hit.
Pfami PF04095. NAPRTase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000484. NAPRT. 1 hit.
SUPFAMi SSF51690. SSF51690. 1 hit.
TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Edwardsiella ictaluri 93-146."
    Williams M.L., Gillaspy A.F., Dyer D.W., Thune R.L., Waldbieser G.C., Schuster S.C., Gipson J., Zaitshik J., Landry C., Lawrence M.L.
    Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 93-146.

Entry informationi

Entry nameiPNCB_EDWI9
AccessioniPrimary (citable) accession number: C5BD56
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: September 3, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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