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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Edwardsiella ictaluri (strain 93-146)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei137 – 1371UniRule annotation
Active sitei544 – 5441UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciEICT634503:GCMY-3826-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:NT01EI_3850
OrganismiEdwardsiella ictaluri (strain 93-146)
Taxonomic identifieri634503 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEdwardsiella
ProteomesiUP000001485 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 877877Phosphoenolpyruvate carboxylasePRO_1000212177Add
BLAST

Proteomic databases

PRIDEiC5BC63.

Interactioni

Protein-protein interaction databases

STRINGi634503.NT01EI_3850.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C5BC63-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNEQYSAMRG NVSMLGKLLG DTIKDALGEE ILDRVETIRR LSKSSRAGNE
60 70 80 90 100
ASRQALLNTL QNLSNDELLP VARAFSQFLN LANVAEQYHR ISPHGEAASN
110 120 130 140 150
PDALYHLFTR LKNKNLDEAQ IRQAVDNLSI ELVLTAHPTE IARRTLIHKL
160 170 180 190 200
VEVNTCLSQL DHDDLADYER HQIMRRLRQL VAQSWHTDEI RKNRPTPIDE
210 220 230 240 250
AKWGYAVVEN SLWEGVPAFL REFNEQLEKS LGYQLPVEAV PVRFTAWMGG
260 270 280 290 300
DRDGNPNVTA EVTRRALLLS RWKAAELFLR DVQVLVSELS MTVCTPELRA
310 320 330 340 350
LAGEHTQEPY REVLKRLRQQ LNNTLTYLDA RLRGERLPRP ADLLVSNDQL
360 370 380 390 400
WQPLHTCYRS LKACGMGIIA NGQLLDTLRR VHCFGVPLVR IDIRQESTRH
410 420 430 440 450
TEALAELTRY LGLGDYETWS EEDKQTFLLR ELNSKRPLVP RHWTPSPETK
460 470 480 490 500
EVFDTCQVIA EAPAGAIAAY VISMARTPSD VLAVHLLLKE AGCPYNLPVV
510 520 530 540 550
PLFETLDDLN NAEAVMTQLL SIDWYRGFIQ GKQMVMIGYS DSAKDAGVMA
560 570 580 590 600
ASWAQYRAQE ALVRVCDNAG IALTLFHGRG GSIGRGGAPA HDALLSQPPG
610 620 630 640 650
SLKSGLRVTE QGEMIRFKLG LPEIAVSSLT LYTSAILEAN LLPPPAPKQE
660 670 680 690 700
WRDVMDELSQ TSCALYRRYI RKNPDFVPYF RSATPELELG KLPLGSRPAK
710 720 730 740 750
RRPSGGVESL RAIPWIFAWT QNRLMLPAWL GAGTALEEAM TEGHRGTLEN
760 770 780 790 800
MYRSWPFFTT RIDMLEMVFA KSDLWLAEYY DQRLVDPALW PLGTELRQQV
810 820 830 840 850
QRDIQAVLTI ADTDHLMADL PWAAESIALR NVYTDPLNVL QAELLYRSRH
860 870
QEQPDANVEQ ALMVTIAGVA AGMRNTG
Length:877
Mass (Da):98,769
Last modified:July 28, 2009 - v1
Checksum:i8E9DCD5542246B5A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001600 Genomic DNA. Translation: ACR70969.1.
RefSeqiWP_015873000.1. NC_012779.2.
YP_002935204.1. NC_012779.2.

Genome annotation databases

EnsemblBacteriaiACR70969; ACR70969; NT01EI_3850.
GeneIDi7959891.
KEGGieic:NT01EI_3850.
PATRICi21840389. VBIEdwIct114273_3435.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001600 Genomic DNA. Translation: ACR70969.1.
RefSeqiWP_015873000.1. NC_012779.2.
YP_002935204.1. NC_012779.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi634503.NT01EI_3850.

Proteomic databases

PRIDEiC5BC63.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACR70969; ACR70969; NT01EI_3850.
GeneIDi7959891.
KEGGieic:NT01EI_3850.
PATRICi21840389. VBIEdwIct114273_3435.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciEICT634503:GCMY-3826-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Edwardsiella ictaluri 93-146."
    Williams M.L., Gillaspy A.F., Dyer D.W., Thune R.L., Waldbieser G.C., Schuster S.C., Gipson J., Zaitshik J., Landry C., Lawrence M.L.
    Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 93-146.

Entry informationi

Entry nameiCAPP_EDWI9
AccessioniPrimary (citable) accession number: C5BC63
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: May 27, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.