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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Edwardsiella ictaluri (strain 93-146)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:NT01EI_1584
OrganismiEdwardsiella ictaluri (strain 93-146)
Taxonomic identifieri634503 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesHafniaceaeEdwardsiella
Proteomesi
  • UP000001485 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002030931 – 577Arginine--tRNA ligaseAdd BLAST577

Proteomic databases

PRIDEiC5B832.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi634503.NT01EI_1584.

Structurei

3D structure databases

ProteinModelPortaliC5B832.
SMRiC5B832.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi122 – 132"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
HOGENOMiHOG000247212.
KOiK01887.
OMAiKLVGNYY.
OrthoDBiPOG091H01RF.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

C5B832-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIQEIISDK VTQALVAAGA PAGSEALVRP SAKVQFGDYQ ANGIMSAAKK
60 70 80 90 100
MGLPPRQLAE QVVANLALDG IASKVEIAGP GFINIFLDAA WLAAQADAAL
110 120 130 140 150
ADPRLGVARV EPQTIVVDYS APNVAKEMHV GHLRSTIIGD AAVRTLEFLG
160 170 180 190 200
HNVIRANHVG DWGTQFGMLI AYLEKVQGSS ETGDMALADL EAFYREAKKH
210 220 230 240 250
YDEDAAFAER ARGYVVKLQG GDEYCREMWR KLVDITMRQN QRNYDRLNVT
260 270 280 290 300
LTDDDVMGES LYNPMLPGIV ADLKAKGLAT ESEGATVVFL NEFRNKEGEP
310 320 330 340 350
MGVIVQKKDG GYLYTTTDIA CAKYRYETLG ANRILYYIDS RQHQHLMQAW
360 370 380 390 400
TIVRKAGYVP DSVSLEHHMF GMMLGKDGKP FKTRAGGTIK LADLLDEAIE
410 420 430 440 450
RAAKLIAAKN PELSGDELKA LVEVVGIGAV KYADLSKNRT TDYIFDWDNM
460 470 480 490 500
LAFEGNTAPY MQYAYTRVAS IFKRAGIDEN TLQGAITLTE EREKALATRL
510 520 530 540 550
MQFEETILSV AREGTPHVMC AYLYEVAGLF SSFYEACPIL NAEEESVRAS
560 570
RLKLAALTAR TLKTGLDTLG IKTVERM
Length:577
Mass (Da):63,483
Last modified:July 28, 2009 - v1
Checksum:i9ED2F7BCE8365D7B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001600 Genomic DNA. Translation: ACR68768.1.
RefSeqiWP_015870926.1. NC_012779.2.

Genome annotation databases

EnsemblBacteriaiACR68768; ACR68768; NT01EI_1584.
GeneIDi7961912.
KEGGieic:NT01EI_1584.
PATRICi21836244. VBIEdwIct114273_1416.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001600 Genomic DNA. Translation: ACR68768.1.
RefSeqiWP_015870926.1. NC_012779.2.

3D structure databases

ProteinModelPortaliC5B832.
SMRiC5B832.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi634503.NT01EI_1584.

Proteomic databases

PRIDEiC5B832.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACR68768; ACR68768; NT01EI_1584.
GeneIDi7961912.
KEGGieic:NT01EI_1584.
PATRICi21836244. VBIEdwIct114273_1416.

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
HOGENOMiHOG000247212.
KOiK01887.
OMAiKLVGNYY.
OrthoDBiPOG091H01RF.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSYR_EDWI9
AccessioniPrimary (citable) accession number: C5B832
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: March 15, 2017
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.