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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Edwardsiella ictaluri (strain 93-146)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciEICT634503:G1GVC-644-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:NT01EI_0694
OrganismiEdwardsiella ictaluri (strain 93-146)
Taxonomic identifieri634503 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesHafniaceaeEdwardsiella
Proteomesi
  • UP000001485 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002040851 – 279Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST279

Interactioni

Protein-protein interaction databases

STRINGi634503.NT01EI_0694

Structurei

3D structure databases

ProteinModelPortaliC5B7N9
SMRiC5B7N9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DDT Bacteria
COG0639 LUCA
HOGENOMiHOG000251871
KOiK01525
OMAiMPWFDVP
OrthoDBiPOG091H0691

Family and domain databases

CDDicd07422 MPP_ApaH, 1 hit
Gene3Di3.60.21.10, 1 hit
HAMAPiMF_00199 ApaH, 1 hit
InterProiView protein in InterPro
IPR004617 ApaH
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF000903 B5n-ttraPtase_sm, 1 hit
TIGRFAMsiTIGR00668 apaH, 1 hit

Sequencei

Sequence statusi: Complete.

C5B7N9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTLLIGDVH GCYHELRDLL SLADFDPARD TLWLTGDLVA RGPDSLAVLR
60 70 80 90 100
YVKSLGDSAR LVLGNHDLHL LAIYAGISRN KPKDKLTPLL EAPDADSLIN
110 120 130 140 150
WLRRQPVLQV DNDLCLVMAH AGISPQWDLT TAQRCAREVE AMLASDSYPF
160 170 180 190 200
FLNAMYGDMP NNWSESLSGL ARLRFTTNAL TRMRYCFPGG ELDMICKDAP
210 220 230 240 250
EDAPAPLRPW FDLDSPVREA GYSIAFGHWA SLEGRSTPPQ VYALDTGCCW
260 270
GGTLTALRWE DRHSFSVPSR RASRHAKAE
Length:279
Mass (Da):31,043
Last modified:July 28, 2009 - v1
Checksum:i4D3D938A44498653
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001600 Genomic DNA Translation: ACR67916.1
RefSeqiWP_015870109.1, NC_012779.2

Genome annotation databases

EnsemblBacteriaiACR67916; ACR67916; NT01EI_0694
GeneIDi7962028
KEGGieic:NT01EI_0694
PATRICifig|634503.3.peg.625

Similar proteinsi

Entry informationi

Entry nameiAPAH_EDWI9
AccessioniPrimary (citable) accession number: C5B7N9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: March 28, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health