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Protein
Submitted name:

Fermentative D-lactate dehydrogenase, NAD-dependent

Gene

ldhA

Organism
Methylobacterium extorquens (strain ATCC 14718 / DSM 1338 / AM1)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Enzyme and pathway databases

BioCyciMEXT272630:GBY6-4526-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Fermentative D-lactate dehydrogenase, NAD-dependentImported (EC:1.1.1.28Imported)
Gene namesi
Name:ldhAImported
Ordered Locus Names:MexAM1_META1p4794Imported
OrganismiMethylobacterium extorquens (strain ATCC 14718 / DSM 1338 / AM1)Imported
Taxonomic identifieri272630 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium
ProteomesiUP000009081 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi272630.MexAM1_META1p4794.

Structurei

3D structure databases

ProteinModelPortaliC5ARS1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1052.
HOGENOMiHOG000136695.
KOiK03778.
OMAiLMMTLNR.
OrthoDBiEOG61VZ8G.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR006139. D-isomer_2_OHA_DH_cat_dom.
IPR029753. D-isomer_DH_CS.
IPR029752. D-isomer_DH_CS1.
IPR006140. D-isomer_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
[Graphical view]
PROSITEiPS00065. D_2_HYDROXYACID_DH_1. 1 hit.
PS00670. D_2_HYDROXYACID_DH_2. 1 hit.
PS00671. D_2_HYDROXYACID_DH_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C5ARS1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDVTIFSTKA YDRRFLDGAN AAAGEPHRLR YLEARLTHES APLTQGAQAV
60 70 80 90 100
CAFVNDVLDR PVLEVLAASG TRMVALRSAG FNNVDLPAAA ELGIAGGRVP
110 120 130 140 150
AYSPDAVAEH TVALILALNR KTHRAYARVR EGNFALEGLL GFDLKGRTVG
160 170 180 190 200
IVGTGKIGRA VARILAGFGC RVLAYDPMPS AELADFGAEA VGLDRLLAEA
210 220 230 240 250
DIVSLHCPLT PDTHHMIDRA ALARMKRGVM LINTGRGALV DTAALIEGLK
260 270 280 290 300
SGVIGDLGLD VYEEEGGLFF EDLSNQIIRD DVFSRLLTFP NVIVTGHQAF
310 320 330
FTAEALAAIA ATTIENLSCF ETQGVPRHPV SVERLA
Length:336
Mass (Da):35,798
Last modified:July 28, 2009 - v1
Checksum:i6B59EA8B8BEE9C3F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001510 Genomic DNA. Translation: ACS42409.1.
RefSeqiWP_003600131.1. NC_012808.1.
YP_002965686.1. NC_012808.1.

Genome annotation databases

EnsemblBacteriaiACS42409; ACS42409; MexAM1_META1p4794.
KEGGimea:Mex_1p4794.
PATRICi22515229. VBIMetExt101010_4666.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001510 Genomic DNA. Translation: ACS42409.1.
RefSeqiWP_003600131.1. NC_012808.1.
YP_002965686.1. NC_012808.1.

3D structure databases

ProteinModelPortaliC5ARS1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272630.MexAM1_META1p4794.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACS42409; ACS42409; MexAM1_META1p4794.
KEGGimea:Mex_1p4794.
PATRICi22515229. VBIMetExt101010_4666.

Phylogenomic databases

eggNOGiCOG1052.
HOGENOMiHOG000136695.
KOiK03778.
OMAiLMMTLNR.
OrthoDBiEOG61VZ8G.

Enzyme and pathway databases

BioCyciMEXT272630:GBY6-4526-MONOMER.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR006139. D-isomer_2_OHA_DH_cat_dom.
IPR029753. D-isomer_DH_CS.
IPR029752. D-isomer_DH_CS1.
IPR006140. D-isomer_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
[Graphical view]
PROSITEiPS00065. D_2_HYDROXYACID_DH_1. 1 hit.
PS00670. D_2_HYDROXYACID_DH_2. 1 hit.
PS00671. D_2_HYDROXYACID_DH_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 14718 / DSM 1338 / AM1Imported.

Entry informationi

Entry nameiC5ARS1_METEA
AccessioniPrimary (citable) accession number: C5ARS1
Entry historyi
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: May 27, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.