C5ARS1 (C5ARS1_METEA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Fermentative D-lactate dehydrogenase, NAD-dependent EMBL ACS42409.1
EC=1.1.1.28 EMBL ACS42409.1

Gene names

Name:	ldhA EMBL ACS42409.1
Ordered Locus Names:	MexAM1_META1p4794 EMBL ACS42409.1

Organism

Methylobacterium extorquens (strain ATCC 14718 / DSM 1338 / AM1) [Complete proteome] [HAMAP] EMBL ACS42409.1

Taxonomic identifier

272630 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium › Methylobacterium extorquens group › Methylobacterium extorquens

Protein attributes

Sequence length	336 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. RuleBase RU003719

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU003720 EMBL ACS42409.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	D-lactate dehydrogenase activity Inferred from electronic annotation. Source: EC NAD binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C5ARS1 [UniParc]. Last modified July 28, 2009. Version 1. Checksum: 6B59EA8B8BEE9C3F	FASTA	336	35,798
	10 20 30 40 50 60 MDVTIFSTKA YDRRFLDGAN AAAGEPHRLR YLEARLTHES APLTQGAQAV CAFVNDVLDR 70 80 90 100 110 120 PVLEVLAASG TRMVALRSAG FNNVDLPAAA ELGIAGGRVP AYSPDAVAEH TVALILALNR 130 140 150 160 170 180 KTHRAYARVR EGNFALEGLL GFDLKGRTVG IVGTGKIGRA VARILAGFGC RVLAYDPMPS 190 200 210 220 230 240 AELADFGAEA VGLDRLLAEA DIVSLHCPLT PDTHHMIDRA ALARMKRGVM LINTGRGALV 250 260 270 280 290 300 DTAALIEGLK SGVIGDLGLD VYEEEGGLFF EDLSNQIIRD DVFSRLLTFP NVIVTGHQAF 310 320 330 FTAEALAAIA ATTIENLSCF ETQGVPRHPV SVERLA

References

[1]

"Methylobacterium genome sequences: a reference blueprint to investigate microbial metabolism of C1 compounds from natural and industrial sources." Vuilleumier S., Chistoserdova L., Lee M.C., Bringel F., Lajus A., Zhou Y., Gourion B., Barbe V., Chang J., Cruveiller S., Dossat C., Gillett W., Gruffaz C., Haugen E., Hourcade E., Levy R., Mangenot S., Muller E. , Nadalig T., Pagni M., Penny C., Peyraud R., Robinson D.G., Roche D., Rouy Z., Saenampechek C., Salvignol G., Vallenet D., Wu Z., Marx C.J., Vorholt J.A., Olson M.V., Kaul R., Weissenbach J., Medigue C., Lidstrom M.E. PLoS ONE 4:E5584-E5584(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 14718 / DSM 1338 / AM1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001510 Genomic DNA. Translation: ACS42409.1.
RefSeq	YP_002965686.1. NC_012808.1.
3D structure databases
ProteinModelPortal	C5ARS1.
ModBase	Search...
Protein-protein interaction databases
STRING	272630.MexAM1_META1p4794.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACS42409; ACS42409; MexAM1_META1p4794.
GeneID	7994567.
KEGG	mea:Mex_1p4794.
PATRIC	22515229. VBIMetExt101010_4666.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1052.
HOGENOM	HOG000136695.
KO	K03778.
OMA	QQFGYEL.
ProtClustDB	CLSK949186.
Enzyme and pathway databases
BioCyc	MEXT272630:GBY6-4526-MONOMER.
Family and domain databases
Gene3D	3.40.50.720. 2 hits.
InterPro	IPR006139. D-isomer_2_OHA_DH_cat_dom. IPR006140. D-isomer_2_OHA_DH_NAD-bd. IPR016040. NAD(P)-bd_dom. [Graphical view]
Pfam	PF00389. 2-Hacid_dh. 1 hit. PF02826. 2-Hacid_dh_C. 1 hit. [Graphical view]
PROSITE	PS00065. D_2_HYDROXYACID_DH_1. 1 hit. PS00670. D_2_HYDROXYACID_DH_2. 1 hit. PS00671. D_2_HYDROXYACID_DH_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C5ARS1_METEA

Accession

Primary (citable) accession number: C5ARS1

Entry history

Integrated into UniProtKB/TrEMBL:	July 28, 2009
Last sequence update:	July 28, 2009
Last modified:	May 29, 2013
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)