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Protein

Putative adenylate kinase

Gene

TGAM_1188

Organism
Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.UniRule annotation

Catalytic activityi

ATP + AMP = 2 ADP.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei96ATPUniRule annotation1
Binding sitei100ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 15ATPUniRule annotation6

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciTGAM593117:G1GUW-1221-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Putative adenylate kinaseUniRule annotation (EC:2.7.4.3UniRule annotation)
Short name:
AKUniRule annotation
Alternative name(s):
ATP-AMP transphosphorylaseUniRule annotation
Gene namesi
Ordered Locus Names:TGAM_1188
OrganismiThermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)
Taxonomic identifieri593117 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus
Proteomesi
  • UP000001488 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002020881 – 177Putative adenylate kinaseAdd BLAST177

Proteomic databases

PaxDbiC5A628

Interactioni

Protein-protein interaction databases

STRINGi593117.TGAM_1188

Structurei

3D structure databases

ProteinModelPortaliC5A628
SMRiC5A628
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni30 – 50NMPbindUniRule annotationAdd BLAST21
Regioni99 – 109LIDUniRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the adenylate kinase family. AK6 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01038 Archaea
COG1936 LUCA
HOGENOMiHOG000224471
KOiK18532
OMAiDNVQCEI
OrthoDBiPOG093Z0F8E

Family and domain databases

HAMAPiMF_00039 Adenylate_kinase_AK6, 1 hit
InterProiView protein in InterPro
IPR020618 Adenyl_kinase_AK6
IPR027417 P-loop_NTPase
PANTHERiPTHR12595:SF0 PTHR12595:SF0, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit

Sequencei

Sequence statusi: Complete.

C5A628-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIIAVTGTPG VGKTTVSKLL AEKLGYEYVS LRDYAIEKGI GEMKGDELEV
60 70 80 90 100
EVDELTYNFE RDFKGKNVVV DGHLSHFLNA DLVVVLRAHP RLIGERLTER
110 120 130 140 150
GYSREKVGEN VEAELVDVIL VEALEENENV IEVDTTGKTP EEVVNEILEL
160 170
IEKGVKKRVG VVDWSEVYDE VIPYLRL
Length:177
Mass (Da):19,887
Last modified:July 28, 2009 - v1
Checksum:i8EA61141143C577C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001398 Genomic DNA Translation: ACS33690.1
RefSeqiWP_015858803.1, NC_012804.1

Genome annotation databases

EnsemblBacteriaiACS33690; ACS33690; TGAM_1188
GeneIDi7988575
KEGGitga:TGAM_1188
PATRICifig|593117.10.peg.1187

Similar proteinsi

Entry informationi

Entry nameiKAD6_THEGJ
AccessioniPrimary (citable) accession number: C5A628
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: May 23, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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