C5A4D6 (RNP2_THEGJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component 2
Short name=RNase P component 2
EC=3.1.26.5

Gene names

Name:	rnp2
Ordered Locus Names:	TGAM_0596

Organism

Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3) [Complete proteome] [HAMAP]

Taxonomic identifier

593117 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus › Thermococcus gammatolerans

Protein attributes

Sequence length	120 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP-Rule MF_00755
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00755
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Molecular_function	ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 120	120	Ribonuclease P protein component 2 HAMAP-Rule MF_00755		PRO_1000212859

Sequences

	Sequence		Length	Mass (Da)
	C5A4D6 [UniParc]. Last modified July 28, 2009. Version 1. Checksum: 6E3E61C45FF3C109	FASTA	120	14,016
	10 20 30 40 50 60 MREKPKYLPP TLREKHRYIA FQLIGERPFR KDEVKKAIWE ASLSTLGVLG SAKAKPWFIR 70 80 90 100 110 120 FDEKSQTGIV RVDRKHVEEL RFALTLVTEI NGSKAIFRTL GVSGTIKRLK RKFLAEFGWR

References

[1]

"Genome analysis and genome-wide proteomics of Thermococcus gammatolerans, the most radioresistant organism known amongst the Archaea." Zivanovic Y., Armengaud J., Lagorce A., Leplat C., Guerin P., Dutertre M., Anthouard V., Forterre P., Wincker P., Confalonieri F. Genome Biol. 10:R70.1-R70.23(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 15229 / JCM 11827 / EJ3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001398 Genomic DNA. Translation: ACS33098.1.
RefSeq	YP_002958962.1. NC_012804.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	593117.TGAM_0596.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACS33098; ACS33098; TGAM_0596.
GeneID	7987219.
KEGG	tga:TGAM_0596.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1369.
HOGENOM	HOG000286243.
KO	K03537.
OMA	NPWLIDY.
ProtClustDB	PRK03717.
Enzyme and pathway databases
BioCyc	TGAM593117:GHFT-611-MONOMER.
Family and domain databases
HAMAP	MF_00755. RNase_P_2.
InterPro	IPR002759. RNase_P/MRP_subunit. IPR016434. RNase_P_comp-2. [Graphical view]
Pfam	PF01900. RNase_P_Rpp14. 1 hit. [Graphical view]
PIRSF	PIRSF004952. RNase_P_2. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RNP2_THEGJ

Accession

Primary (citable) accession number: C5A4D6

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	July 28, 2009
Last modified:	May 29, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program