Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

C5A448 (C5A448_THEGJ) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Protein attributes

Sequence length194 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP-Rule MF_00124

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00124

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00124.

Sequence similarities

Belongs to the thymidine kinase family. HAMAP-Rule MF_00124

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding12 – 198ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding90 – 934ATP By similarity HAMAP-Rule MF_00124

Sites

Active site911Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1471Zinc By similarity HAMAP-Rule MF_00124
Metal binding1501Zinc By similarity HAMAP-Rule MF_00124
Metal binding1851Zinc By similarity HAMAP-Rule MF_00124
Metal binding1881Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
C5A448 [UniParc].

Last modified July 28, 2009. Version 1.
Checksum: A0983945177866EE

FASTA19421,810
        10         20         30         40         50         60 
MHPGGFLEVI TGPMFAGKTT ELIKRIERQA FARRKVALFK PSIDTRYSKE EVVAHNGLRY 

        70         80         90        100        110        120 
EAFVVPTDEN GVRRIMETTI REGFEVIGID EVQFFPIEIV DVLNRLADEG VYVIASGLNL 

       130        140        150        160        170        180 
DFKGDPFPVT RELLVRADNI VYLTAVCTVC GRPATRSQRL IDGKPAPRNS PVILVGGRES 

       190 
YEARCREHHI VPEE 

« Hide

References

[1]"Genome analysis and genome-wide proteomics of Thermococcus gammatolerans, the most radioresistant organism known amongst the Archaea."
Zivanovic Y., Armengaud J., Lagorce A., Leplat C., Guerin P., Dutertre M., Anthouard V., Forterre P., Wincker P., Confalonieri F.
Genome Biol. 10:R70.1-R70.23(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 15229 / JCM 11827 / EJ3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001398 Genomic DNA. Translation: ACS33010.1.
RefSeqYP_002958874.1. NC_012804.1.

3D structure databases

ProteinModelPortalC5A448.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING593117.TGAM_0508.

Proteomic databases

PaxDbC5A448.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACS33010; ACS33010; TGAM_0508.
GeneID7987376.
KEGGtga:TGAM_0508.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1435.
HOGENOMHOG000076390.
KOK00857.
OMAELICGSM.
ProtClustDBPRK04296.

Enzyme and pathway databases

BioCycTGAM593117:GHFT-523-MONOMER.

Family and domain databases

HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC5A448_THEGJ
AccessionPrimary (citable) accession number: C5A448
Entry history
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: April 16, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)