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Protein

Protein-export membrane protein SecD

Gene

secD

Organism
Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in protein export.UniRule annotation

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Protein-export membrane protein SecDUniRule annotation
Gene namesi
Name:secDUniRule annotation
Ordered Locus Names:TGAM_0284
OrganismiThermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)
Taxonomic identifieri593117 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus
Proteomesi
  • UP000001488 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei16 – 36HelicalUniRule annotationAdd BLAST21
Transmembranei368 – 388HelicalUniRule annotationAdd BLAST21
Transmembranei395 – 415HelicalUniRule annotationAdd BLAST21
Transmembranei421 – 441HelicalUniRule annotationAdd BLAST21
Transmembranei466 – 486HelicalUniRule annotationAdd BLAST21
Transmembranei488 – 508HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004126891 – 525Protein-export membrane protein SecDAdd BLAST525

Proteomic databases

PaxDbiC5A3H4.
PRIDEiC5A3H4.

Interactioni

Subunit structurei

Part of the protein translocation apparatus. Forms a complex with SecF.UniRule annotation

Protein-protein interaction databases

STRINGi593117.TGAM_0284.

Family & Domainsi

Sequence similaritiesi

Belongs to the SecD/SecF family. SecD subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiarCOG03055. Archaea.
COG0342. LUCA.
HOGENOMiHOG000227492.
KOiK03072.

Family and domain databases

HAMAPiMF_01463_A. SecD_A. 1 hit.
InterProiIPR022813. SecD/SecF_arch_bac.
IPR024912. SecD_arc.
[Graphical view]
PfamiPF02355. SecD_SecF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C5A3H4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARKKGVKAL LLNWRVLLLI LFLIGSVVSM SIKGLTYGID IGGGVALIAE
60 70 80 90 100
PEKPVSKDTL NGIITSLQNR LNTFGVKDIT IEAQHDPETG QSLIVVKIAN
110 120 130 140 150
VTLDEANQIK DLIESQGVLY MEFNGVIFAT GTDVTVHSSD YGLDLQECPT
160 170 180 190 200
CWYVGFELSG KAQNKFKKIA AGKLGWPIDI YLDPPVNSLL VVSPRVYQEM
210 220 230 240 250
NSGDFMGAPS EGTPKPLVER LKEAFNITVV EYSNQTAEDI VENATALGKD
260 270 280 290 300
KIILADVPEE LYNDVRELVL SKDLKLRVSH YTPQQGEDLK DFVKRILNLY
310 320 330 340 350
GPYVLKFDPA KGETTRLKLS GSAPTKEEAL QEARKIYSVL RSGSLAVKLH
360 370 380 390 400
VVSEEYISPT LGASFKKQAI IAGIGALIAV LLIVYFHYRR WRIAIPVAST
410 420 430 440 450
SLFEVIIILG IAALIRWNLD LPSIAGIIAA IGTGVDQQIV ITDELLGGTA
460 470 480 490 500
GRVTRRMSAL RRMARAFFII FASAATTIVA MSFLLVYFVG TLKGFAVTTI
510 520
LGVLIGVLVT RPAYAEIAKY LLSLE
Length:525
Mass (Da):57,348
Last modified:July 28, 2009 - v1
Checksum:i66FF6EF17C5225C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001398 Genomic DNA. Translation: ACS32786.1.
RefSeqiWP_015857905.1. NC_012804.1.

Genome annotation databases

EnsemblBacteriaiACS32786; ACS32786; TGAM_0284.
GeneIDi7988940.
KEGGitga:TGAM_0284.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001398 Genomic DNA. Translation: ACS32786.1.
RefSeqiWP_015857905.1. NC_012804.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi593117.TGAM_0284.

Proteomic databases

PaxDbiC5A3H4.
PRIDEiC5A3H4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACS32786; ACS32786; TGAM_0284.
GeneIDi7988940.
KEGGitga:TGAM_0284.

Phylogenomic databases

eggNOGiarCOG03055. Archaea.
COG0342. LUCA.
HOGENOMiHOG000227492.
KOiK03072.

Family and domain databases

HAMAPiMF_01463_A. SecD_A. 1 hit.
InterProiIPR022813. SecD/SecF_arch_bac.
IPR024912. SecD_arc.
[Graphical view]
PfamiPF02355. SecD_SecF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSECD_THEGJ
AccessioniPrimary (citable) accession number: C5A3H4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 21, 2011
Last sequence update: July 28, 2009
Last modified: November 2, 2016
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.