C5A316 (C5A316_THEGJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA polymerase II large subunit DP2, intein containing (Dp2/polC) EMBL ACS32628.1
EC=2.7.7.7 EMBL ACS32628.1

Gene names

Name:	dp2 EMBL ACS32628.1
Ordered Locus Names:	TGAM_0126

Organism

Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3) [Complete proteome] [HAMAP] EMBL ACS32628.1

Taxonomic identifier

593117 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus

Protein attributes

Sequence length	1459 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

Ontologies

Keywords
Molecular function	Nucleotidyltransferase EMBL ACS32628.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA catabolic process Inferred from electronic annotation. Source: InterPro DNA replication Inferred from electronic annotation. Source: InterPro intein-mediated protein splicing Inferred from electronic annotation. Source: InterPro
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1459	1459	DNA polymerase II large subunit DP2 EMBL ACS32628.1		PRO_5000468303
	Chain	926 – 1126	201	intein EMBL ACS32628.1		PRO_5000468304

Sequences

	Sequence		Length	Mass (Da)
	C5A316 [UniParc]. Last modified July 28, 2009. Version 1. Checksum: 5BFED700D24348F5	FASTA	1,459	166,749
	10 20 30 40 50 60 MGDELYSPGM KAYFESLQRE IDRAYEIARK ARSQGKDPSL DVEVPQATDM AGRVESLVGP 70 80 90 100 110 120 PGVAERIRVL VKEYGKELAA LKVVDEIIEG KFGDLGSKER YAEQAVRTAL AILTEGIVSA 130 140 150 160 170 180 PLEGIADVKI KRNTWADNSE YLALYYAGPI RSSGGTAQAL SVLVGDYVRK KLGLDRFKPS 190 200 210 220 230 240 EEHIERMVEE IDLYHRAVTR LQYHPEADEV RLAMRNIPIE ITGEETDKVE VSHRNVPGVE 250 260 270 280 290 300 TNHLRGGAIL VLAEGVLQKA KKLVKYIDKM GVEGWDWIKE FVEAKEKGKS EEPKADESKA 310 320 330 340 350 360 EDSGAREEIT EKVEKGFYYE LYERFKANIA PNKKYTKEII GGRPLFAEPS ENGGFRLRYG 370 380 390 400 410 420 RSRVSGFATW SVNPATMLIL DEFIAIGTQM KTERPGKGCI VTPATTVEGP IVKLKDGSVV 430 440 450 460 470 480 RVDDYETALR VKNEIEEILY VGDALVNFGD FVENNQTLLP ANYVEEWWVQ ELVKAIEELY 490 500 510 520 530 540 EVELKPFSDN PREAIEEAAE YLEIDPDFLE SLLRDPLRVR PSVELAIHLS KVLDIPFHPY 550 560 570 580 590 600 YTLYWNTLKP EEVEELQRAL LNAQIEWDEF RKLKFARKVI LDNDPRIKRY LELLGLPHRL 610 620 630 640 650 660 ERTEDRRKVI VVDYPWSAAL LTPLGNLEWE FKAKPFHTVI DIINENNPIK LRDRGISWIG 670 680 690 700 710 720 ARMGRPEKAK ERKMKPPVQV LFPIGLAGGQ SRDIKKAAEE GKTAKVEIAF FRCPKCGHVG 730 740 750 760 770 780 PEHLCPVCGT RKELLWHCPK CNVDYPESEA KEFGFRCPRC DVELRPYAER EIKPSELLRR 790 800 810 820 830 840 AMENVKVYGI DRLKGVKGMT SGYKMAEPLE KGLLRVKNDV YVFKDGTIRF DATDAPITHF 850 860 870 880 890 900 KPKEIGVSVE KLRELGYTHD FEGKPLERDD QIVELKVQDI ILSYEAGKYL LKVARFVDDL 910 920 930 940 950 960 LEKFYGLPRF YNAEKMEDLI GHLVIGLAPH TSAGIIGRII GFSDVLVGYA HPYYHAAKRR 970 980 990 1000 1010 1020 NCFPGDTRIL VQIDGKPARI TLRELYELFE GESYENMVYV RRKPKRDVKV YSFDPERGKV 1030 1040 1050 1060 1070 1080 VLTDIEDVIK APSTDHLIRF ELELGRSFET TVDHPVLVYE NGKFVEKRAF EVKEGELIGV 1090 1100 1110 1120 1130 1140 YENDSIKPFK IERIKYVKPK DDFVFSLNAK SYHNVLINEN VVTHQCDGDE DAVMLLLDAL 1150 1160 1170 1180 1190 1200 LNFSKYYLPE KRGGKMDAPL VVTTRLDPRE VDSEVHNMDV VRYYPLEFYE ATYEMKSPKE 1210 1220 1230 1240 1250 1260 IKFIERVEDR LGKPEMYEGI KFTHDTDDIG LGPKMSLYKQ LGDMVEKVER QLALAERIRA 1270 1280 1290 1300 1310 1320 VDEHHVAETI LNSHLIPDLR GNLRSFTRQE FRCVKCNTKY RRPPLTGRCP KCGGKIVLTV 1330 1340 1350 1360 1370 1380 SKGAVEKYLP TAKMLVTRYN VKDYTRQRIC LTEKDIKTLF ETVLPEKQRT LLGFSADVCE 1390 1400 1410 1420 1430 1440 KMIKERTGSS NGKNGYLDGF NGKNGKVGKA KTSKEVEKKN DAESRTKKKP SENLKKEVKK 1450 EKAKAKRKKR ISLDEFFGS

References

[1]

"Genome analysis and genome-wide proteomics of Thermococcus gammatolerans, the most radioresistant organism known amongst the Archaea." Zivanovic Y., Armengaud J., Lagorce A., Leplat C., Guerin P., Dutertre M., Anthouard V., Forterre P., Wincker P., Confalonieri F. Genome Biol. 10:R70.1-R70.23(2007) [PubMed: 19558674] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 15229 / JCM 11827 / EJ3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001398 Genomic DNA. Translation: ACS32628.1.
RefSeq	YP_002958492.1. NC_012804.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	C5A316.
Protein family/group databases
MEROPS	N10.005.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7988706.
GenomeReviews	Gene locus TGAM_0126 in contig CP001398_GR.
KEGG	tga:TGAM_0126.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	NCDGDED.
ProtClustDB	PRK14714.
Family and domain databases
HAMAP	MF_00324. DNApol_II_L_arch. [Tree]
InterPro	IPR003586. Hedgehog_hint_C. IPR003587. Hedgehog_hint_N. IPR006141. Intein_splice_site. IPR004475. PolC_DP2. IPR016033. PolC_DP2_N. [Graphical view]
KO	K02322.
Pfam	PF03833. PolC_DP2. 1 hit. [Graphical view]
SMART	SM00305. HintC. 1 hit. SM00306. HintN. 1 hit. [Graphical view]
TIGRFAMs	TIGR01445. Intein_Nterm. 1 hit. TIGR00354. PolC. 1 hit.
PROSITE	PS50818. INTEIN_C_TER. 1 hit. PS50817. INTEIN_N_TER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C5A316_THEGJ

Accession

Primary (citable) accession number: C5A316

Entry history

Integrated into UniProtKB/TrEMBL:	July 28, 2009
Last sequence update:	July 28, 2009
Last modified:	December 14, 2011
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)