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Protein
Submitted name:

Fused predicted acyl-CoA synthetase: NAD(P)-binding subunit/ATP-binding subunit

Gene

yfiQ

Organism
Escherichia coli (strain K12 / MC4100 / BW2952)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. cofactor binding Source: InterPro
  3. metal ion binding Source: InterPro
  4. N-acetyltransferase activity Source: InterPro
Complete GO annotation...

Keywords - Ligandi

ATP-bindingImported, Nucleotide-binding

Enzyme and pathway databases

BioCyciECOL595496:GI18-2430-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Fused predicted acyl-CoA synthetase: NAD(P)-binding subunit/ATP-binding subunitImported
Gene namesi
Name:yfiQImported
Ordered Locus Names:BWG_2348Imported
OrganismiEscherichia coli (strain K12 / MC4100 / BW2952)Imported
Taxonomic identifieri595496 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000001478 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi595496.BWG_2348.

Structurei

3D structure databases

ProteinModelPortaliC4ZYK7.
SMRiC4ZYK7. Positions 6-445, 465-679, 718-862.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG1042.
HOGENOMiHOG000220090.
KOiK09181.
OMAiFAILVRS.
OrthoDBiEOG6FFS5B.

Family and domain databases

Gene3Di3.30.470.20. 1 hit.
3.40.50.261. 2 hits.
3.40.50.720. 1 hit.
3.40.630.30. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR011761. ATP-grasp.
IPR013816. ATP_grasp_subdomain_2.
IPR003781. CoA-bd.
IPR000182. GNAT_dom.
IPR016040. NAD(P)-bd_dom.
IPR016102. Succinyl-CoA_synth-like.
[Graphical view]
PfamiPF00583. Acetyltransf_1. 1 hit.
PF13380. CoA_binding_2. 1 hit.
[Graphical view]
SMARTiSM00881. CoA_binding. 1 hit.
[Graphical view]
SUPFAMiSSF52210. SSF52210. 2 hits.
SSF55729. SSF55729. 1 hit.
PROSITEiPS50975. ATP_GRASP. 1 hit.
PS51186. GNAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C4ZYK7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQRGLEALL RPKSIAVIGA SMKPNRAGYL MMRNLLAGGF NGPVLPVTPA
60 70 80 90 100
WKAVLGVLAW PDIASLPFTP DLAVLCTNAS RNLALLEELG EKGCKTCIIL
110 120 130 140 150
SAPASQHEDL RACALRHNMR LLGPNSLGLL APWQGLNASF SPVPIKRGKL
160 170 180 190 200
AFISQSAAVS NTILDWAQQR KMGFSYFIAL GDSLDIDVDE LLDYLARDSK
210 220 230 240 250
TSAILLYLEQ LSDARRFVSA ARSASRNKPI LVIKSGRSPA AQRLLNTTAG
260 270 280 290 300
MDPAWDAAIQ RAGLLRVQDT HELFSAVETL SHMRPLRGDR LMIISNGAAP
310 320 330 340 350
AALALDALWS RNGKLATLSE ETCQKLRDAL PEHVAISNPL DLRDDASSEH
360 370 380 390 400
YIKTLDILLH SQDFDALMVI HSPSAAAPAT ESAQVLIEAV KHHPRSKYVS
410 420 430 440 450
LLTNWCGEHS SQEARRLFSE AGLPTYRTPE GTITAFMHMV EYRRNQKQLR
460 470 480 490 500
ETPALPSNLT SNTAEAHLLL QQAIAEGATS LDTHEVQPIL QAYGMNTLPT
510 520 530 540 550
WIASDSTEAV HIAEQIGYPV ALKLRSPDIP HKSEVQGVML YLRTANEVQQ
560 570 580 590 600
AANAIFDRVK MAWPQARVHG LLVQSMANRA GAQELRVVVE HDPVFGPLIM
610 620 630 640 650
LGEGGVEWRP EDQAVVALPP LNMNLARYLV IQGIKSKKIR ARSALRPLDV
660 670 680 690 700
AGLSQLLVQV SNLIVDCPEI QRLDIHPLLA SGSEFTALDV TLDISPFEGD
710 720 730 740 750
NESRLAVRPY PHQLEEWVEL KNGERCLFRP ILPEDEPQLQ QFISRVTKED
760 770 780 790 800
LYYRYFSEIN EFTHEDLANM TQIDYDREMA FVAVRRIDQT EEILGVTRAI
810 820 830 840 850
SDPDNIDAEF AVLVRSDLKG LGLGRRLMEK LITYTRDHGL QRLNGITMPN
860 870 880
NRGMVALARK LGFNVDIQLE EGIVGLTLNL AQREES
Length:886
Mass (Da):97,987
Last modified:July 28, 2009 - v1
Checksum:i255944B9E2961251
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001396 Genomic DNA. Translation: ACR63218.1.
RefSeqiYP_002927545.1. NC_012759.1.

Genome annotation databases

EnsemblBacteriaiACR63218; ACR63218; BWG_2348.
KEGGiebw:BWG_2348.
PATRICi18274102. VBIEscCol60876_2568.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001396 Genomic DNA. Translation: ACR63218.1.
RefSeqiYP_002927545.1. NC_012759.1.

3D structure databases

ProteinModelPortaliC4ZYK7.
SMRiC4ZYK7. Positions 6-445, 465-679, 718-862.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi595496.BWG_2348.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACR63218; ACR63218; BWG_2348.
KEGGiebw:BWG_2348.
PATRICi18274102. VBIEscCol60876_2568.

Phylogenomic databases

eggNOGiCOG1042.
HOGENOMiHOG000220090.
KOiK09181.
OMAiFAILVRS.
OrthoDBiEOG6FFS5B.

Enzyme and pathway databases

BioCyciECOL595496:GI18-2430-MONOMER.

Family and domain databases

Gene3Di3.30.470.20. 1 hit.
3.40.50.261. 2 hits.
3.40.50.720. 1 hit.
3.40.630.30. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR011761. ATP-grasp.
IPR013816. ATP_grasp_subdomain_2.
IPR003781. CoA-bd.
IPR000182. GNAT_dom.
IPR016040. NAD(P)-bd_dom.
IPR016102. Succinyl-CoA_synth-like.
[Graphical view]
PfamiPF00583. Acetyltransf_1. 1 hit.
PF13380. CoA_binding_2. 1 hit.
[Graphical view]
SMARTiSM00881. CoA_binding. 1 hit.
[Graphical view]
SUPFAMiSSF52210. SSF52210. 2 hits.
SSF55729. SSF55729. 1 hit.
PROSITEiPS50975. ATP_GRASP. 1 hit.
PS51186. GNAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genomic sequencing reveals regulatory mutations and recombinational events in the widely used MC4100 lineage of Escherichia coli K-12."
    Ferenci T., Zhou Z., Betteridge T., Ren Y., Liu Y., Feng L., Reeves P.R., Wang L.
    J. Bacteriol. 191:4025-4029(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MC4100 / BW2952Imported.

Entry informationi

Entry nameiC4ZYK7_ECOBW
AccessioniPrimary (citable) accession number: C4ZYK7
Entry historyi
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: April 1, 2015
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.