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C4ZY76 (C4ZY76_ECOBW) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Mannose-6-phosphate isomerase RuleBase RU000611
EC=5.3.1.8 RuleBase RU000611
Gene names
Name:manA EMBL ACR63724.1
Ordered Locus Names:BWG_1428
OrganismEscherichia coli (strain K12 / MC4100 / BW2952) [Complete proteome] [HAMAP]
Taxonomic identifier595496 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia ›

Protein attributes

Sequence length391 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-mannose 6-phosphate = D-fructose 6-phosphate. RuleBase RU000611

Cofactor

Binds 1 zinc ion per subunit By similarity. RuleBase RU000611

Sequence similarities

Belongs to the mannose-6-phosphate isomerase type 1 family. RuleBase RU004189

Sequences

Sequence LengthMass (Da)Tools
C4ZY76 [UniParc].

Last modified July 28, 2009. Version 1.
Checksum: 669737512CADBCCD

FASTA39142,850
        10         20         30         40         50         60 
MQKLINSVQN YAWGSKTALT ELYGMENPSS QPMAELWMGA HPKSSSRVQN AAGDIVSLRD 

        70         80         90        100        110        120 
VIESDKSTLL GEAVAKRFGE LPFLFKVLCA AQPLSIQVHP NKHNSEIGFA KENAAGIPMD 

       130        140        150        160        170        180 
AAERNYKDPN HKPELVFALT PFLAMNAFRE FSEIVSLLQP VAGAHPAIAH FLQQPDAERL 

       190        200        210        220        230        240 
SELFASLLNM QGEEKSRALA ILKSALDSQQ GEPWQTIRLI SEFYPEDSGL FSPLLLNVVK 

       250        260        270        280        290        300 
LNPGEAMFLF AETPHAYLQG VALEVMANSD NVLRAGLTPK YIDIPELVAN VKFEAKPANQ 

       310        320        330        340        350        360 
LLTQPVKQGA ELDFPIPVDD FAFSLHDLSD KETTISQQSA AILFCVEGDA TLWKGSQQLQ 

       370        380        390 
LKPGESAFIA ANESPVTVKG HGRLARVYNK L

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References

[1]"Genomic sequencing reveals regulatory mutations and recombinational events in the widely used MC4100 lineage of Escherichia coli K-12."
Ferenci T., Zhou Z., Betteridge T., Ren Y., Liu Y., Feng L., Reeves P.R., Wang L.
J. Bacteriol. 191:4025-4029(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MC4100 / BW2952.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001396 Genomic DNA. Translation: ACR63724.1.
RefSeqYP_002926625.1. NC_012759.1.

3D structure databases

ProteinModelPortalC4ZY76.
SMRC4ZY76. Positions 1-391.
ModBaseSearch...

Protein-protein interaction databases

STRING595496.BWG_1428.
C4ZY76.

Proteomic databases

PRIDEC4ZY76.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACR63724; ACR63724; BWG_1428.
GeneID7953642.
KEGGebw:BWG_1428.
PATRIC18272077. VBIEscCol60876_1573.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1482.
HOGENOMHOG000241278.
KOK01809.
OMAVMKMEVP.
ProtClustDBPRK15131.

Enzyme and pathway databases

BioCycECOL595496:GI18-2182-MONOMER.

Family and domain databases

Gene3D2.60.120.10. 3 hits.
InterProIPR001250. Man6P_Isoase-1.
IPR016305. Mannose-6-P_Isomerase.
IPR018050. Pmannose_isomerase-type1_CS.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view]
PANTHERPTHR10309. PTHR10309. 1 hit.
PfamPF01238. PMI_typeI. 1 hit.
[Graphical view]
PIRSFPIRSF001480. Mannose-6-phosphate_isomerase. 1 hit.
PRINTSPR00714. MAN6PISMRASE.
SUPFAMSSF51182. RmlC_like_cupin. 1 hit.
TIGRFAMsTIGR00218. manA. 1 hit.
PROSITEPS00965. PMI_I_1. 1 hit.
PS00966. PMI_I_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC4ZY76_ECOBW
AccessionPrimary (citable) accession number: C4ZY76
Entry history
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: May 1, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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