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C4ZTZ8

- C4ZTZ8_ECOBW

UniProt

C4ZTZ8 - C4ZTZ8_ECOBW

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Protein
Submitted name:

GABA aminotransferase, PLP-dependent

Gene

puuE

Organism
Escherichia coli (strain K12 / MC4100 / BW2952)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. 4-aminobutyrate transaminase activity Source: InterPro
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. gamma-aminobutyric acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciECOL595496:GI18-1177-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
GABA aminotransferase, PLP-dependentImported
Gene namesi
Name:puuEImported
Ordered Locus Names:BWG_1134Imported
OrganismiEscherichia coli (strain K12 / MC4100 / BW2952)Imported
Taxonomic identifieri595496 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000001478: Chromosome

PTM / Processingi

Proteomic databases

PRIDEiC4ZTZ8.

Interactioni

Protein-protein interaction databases

STRINGi595496.BWG_1134.

Structurei

3D structure databases

ProteinModelPortaliC4ZTZ8.
SMRiC4ZTZ8. Positions 2-421.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0160.
HOGENOMiHOG000020206.
KOiK00823.
OMAiRPWILAF.
OrthoDBiEOG6QVRHN.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C4ZTZ8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSNNEFHQRR LSATPRGVGV MCNFFAQSAE NATLKDVEGN EYIDFAAGIA
60 70 80 90 100
VLNTGHRHPD LVAAVEQQLQ QFTHTAYQIV PYESYVTLAE KINALAPVSG
110 120 130 140 150
QAKTAFFTTG AEAVENAVKI ARAHTGRPGV IAFSGGFHGR TYMTMALTGK
160 170 180 190 200
VAPYKIGFGP FPGSVYHVPY PSDLHGISTQ DSLDAIERLF KSDIEAKQVA
210 220 230 240 250
AIIFEPVQGE GGFNVAPKEL VAAIRRLCDE HGIVMIADEV QSGFARTGKL
260 270 280 290 300
FAMDHYADKP DLMTMAKSLA GGMPLSGVVG NANIMDAPAP GGLGGTYAGN
310 320 330 340 350
PLAVAAAHAV LNIIDKESLC ERANQLGQRL KNTLIDAKES VPAIAAVRGL
360 370 380 390 400
GSMIAVEFND PQTGEPSAAI AQKIQQRALA QGLLLLTCGA YGNVIRFLYP
410 420
LTIPDAQFDA AMKILQDALS D
Length:421
Mass (Da):44,729
Last modified:July 28, 2009 - v1
Checksum:iA2C17A885FEBE4EB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001396 Genomic DNA. Translation: ACR63262.1.
RefSeqiYP_002926334.1. NC_012759.1.

Genome annotation databases

EnsemblBacteriaiACR63262; ACR63262; BWG_1134.
GeneIDi7953766.
KEGGiebw:BWG_1134.
PATRICi18271417. VBIEscCol60876_1243.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001396 Genomic DNA. Translation: ACR63262.1 .
RefSeqi YP_002926334.1. NC_012759.1.

3D structure databases

ProteinModelPortali C4ZTZ8.
SMRi C4ZTZ8. Positions 2-421.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 595496.BWG_1134.

Proteomic databases

PRIDEi C4ZTZ8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACR63262 ; ACR63262 ; BWG_1134 .
GeneIDi 7953766.
KEGGi ebw:BWG_1134.
PATRICi 18271417. VBIEscCol60876_1243.

Phylogenomic databases

eggNOGi COG0160.
HOGENOMi HOG000020206.
KOi K00823.
OMAi RPWILAF.
OrthoDBi EOG6QVRHN.

Enzyme and pathway databases

BioCyci ECOL595496:GI18-1177-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProi IPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view ]
PANTHERi PTHR11986. PTHR11986. 1 hit.
Pfami PF00202. Aminotran_3. 1 hit.
[Graphical view ]
PIRSFi PIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMi SSF53383. SSF53383. 1 hit.
TIGRFAMsi TIGR00700. GABAtrnsam. 1 hit.
PROSITEi PS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genomic sequencing reveals regulatory mutations and recombinational events in the widely used MC4100 lineage of Escherichia coli K-12."
    Ferenci T., Zhou Z., Betteridge T., Ren Y., Liu Y., Feng L., Reeves P.R., Wang L.
    J. Bacteriol. 191:4025-4029(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MC4100 / BW2952Imported.

Entry informationi

Entry nameiC4ZTZ8_ECOBW
AccessioniPrimary (citable) accession number: C4ZTZ8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: October 1, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3