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C4ZTG1 (ACPH_ECOBW) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Acyl carrier protein phosphodiesterase

Short name=ACP phosphodiesterase
EC=3.1.4.14
Gene names
Name:acpH
Ordered Locus Names:BWG_0286
OrganismEscherichia coli (strain K12 / MC4100 / BW2952) [Complete proteome] [HAMAP]
Taxonomic identifier595496 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length193 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP By similarity. HAMAP-Rule MF_01950

Catalytic activity

Holo-[acyl-carrier-protein] + H2O = 4'-phosphopantetheine + apo-[acyl-carrier-protein]. HAMAP-Rule MF_01950

Sequence similarities

Belongs to the AcpH family.

Ontologies

Keywords
   Biological processFatty acid biosynthesis
Fatty acid metabolism
Lipid biosynthesis
Lipid metabolism
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processfatty acid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_function[acyl-carrier-protein] phosphodiesterase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 193193Acyl carrier protein phosphodiesterase HAMAP-Rule MF_01950
PRO_1000216193

Sequences

Sequence LengthMass (Da)Tools
C4ZTG1 [UniParc].

Last modified July 28, 2009. Version 1.
Checksum: 0DE6F0CE01D6C523

FASTA19322,961
        10         20         30         40         50         60 
MNFLAHLHLA HLAESSLSGN LLADFVRGNP EESFPPDVVA GIHMHRRIDV LTDNLPEVRE 

        70         80         90        100        110        120 
AREWFRSETR RVAPITLDVM WDHFLSRHWS QLSPDFPLQE FVCYAREQVM TILPDSPPRF 

       130        140        150        160        170        180 
INLNNYLWSE QWLVRYRDMD FIQNVLNGMA SRRPRLDALR DSWYDLDAHY DALETRFWQF 

       190 
YPRMMAQASR KAL 

« Hide

References

[1]"Genomic sequencing reveals regulatory mutations and recombinational events in the widely used MC4100 lineage of Escherichia coli K-12."
Ferenci T., Zhou Z., Betteridge T., Ren Y., Liu Y., Feng L., Reeves P.R., Wang L.
J. Bacteriol. 191:4025-4029(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MC4100 / BW2952.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001396 Genomic DNA. Translation: ACR62270.1.
RefSeqYP_002925488.1. NC_012759.1.

3D structure databases

ProteinModelPortalC4ZTG1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING595496.BWG_0286.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACR62270; ACR62270; BWG_0286.
GeneID7954203.
KEGGebw:BWG_0286.
PATRIC18269534. VBIEscCol60876_0323.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3124.
HOGENOMHOG000275880.
KOK08682.
OMAWLHRQID.
OrthoDBEOG6K6V7H.
ProtClustDBPRK10045.

Enzyme and pathway databases

BioCycECOL595496:GI18-298-MONOMER.

Family and domain databases

HAMAPMF_01950. AcpH.
InterProIPR007431. ACP_phosphodiesterase.
IPR023491. ACP_phosphodiesterase_gpbac.
[Graphical view]
PfamPF04336. DUF479. 1 hit.
[Graphical view]
PIRSFPIRSF011489. DUF479. 1 hit.
ProtoNetSearch...

Entry information

Entry nameACPH_ECOBW
AccessionPrimary (citable) accession number: C4ZTG1
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: February 19, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families