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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Agathobacter rectalis (strain ATCC 33656 / DSM 3377 / JCM 17463 / KCTC 5835 / VPI 0990) (Eubacterium rectale)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:EUBREC_2239
OrganismiAgathobacter rectalis (strain ATCC 33656 / DSM 3377 / JCM 17463 / KCTC 5835 / VPI 0990) (Eubacterium rectale)
Taxonomic identifieri515619 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesLachnospiraceae
Proteomesi
  • UP000001477 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002030941 – 597Arginine--tRNA ligaseAdd BLAST597

Proteomic databases

PRIDEiC4ZD15

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliC4ZD15
SMRiC4ZD15
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi124 – 134"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000247212
KOiK01887
OMAiALCVFFD
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

C4ZD15-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKLINLISE EVTKAFVSAG YDEKYGKVTL SNRPDLCEFQ CNGAMAAAKE
60 70 80 90 100
YKCAPFMISD KVAALLESDE MFESVESVKP GFLNIKMDTA FLAKYMNDMK
110 120 130 140 150
DDEGRYGLEK AKKPLTIVVD YGGPNVAKPL HVGHLRSAVI GESVKRIAKF
160 170 180 190 200
MGHNVIGDVH LGDWGLQMGL IITELRERKP DLVYFDESYT GEYPKEAPFT
210 220 230 240 250
ISELEDIYPT ASGKSKSDES FKEAALLATK ELQGGRRGYQ ALLSHIMNVS
260 270 280 290 300
VTDLKRNYEN LNVHFELWKG ESDAQPYVPG MVEMMKEKGF AHMSEGALVV
310 320 330 340 350
DVKEDTDTKE IPPCIILKSD GASLYSTTDL ATLVMRMKEN NPDRVIYLAD
360 370 380 390 400
ARQSMHFIQV FRCARKTGIV PDTTELVHIG FGTMNGKDGK PFKTRDGGVM
410 420 430 440 450
RLEYLLKEID DEMLNKIKEN QKEKENLNID EAEAEQTAKT VALAAVKYGD
460 470 480 490 500
LSNQASKDYI FDIDRFTSFE GNTGPYILYT IVRIKSILSK YEAKGGDISA
510 520 530 540 550
LKDAIMPAVN AGQKNLMLSL AKFNATIESA YEESAPHKIC AYIYELANAF
560 570 580 590
NGFYHDTKIL SEENEELKKS YISLLVLTKE ILEACIDMLG FSAPDRM
Length:597
Mass (Da):66,744
Last modified:July 28, 2009 - v1
Checksum:iC0B7B15F19EABD3A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001107 Genomic DNA Translation: ACR75978.1
RefSeqiWP_012743073.1, NC_012781.1

Genome annotation databases

EnsemblBacteriaiACR75978; ACR75978; EUBREC_2239
KEGGiere:EUBREC_2239

Similar proteinsi

Entry informationi

Entry nameiSYR_AGARV
AccessioniPrimary (citable) accession number: C4ZD15
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: May 23, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

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