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Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Eubacterium eligens (strain ATCC 27750 / VPI C15-48)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei66L-glutamineUniRule annotation1
Binding sitei211L-glutamineUniRule annotation1
Binding sitei230ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi34 – 36ATPUniRule annotation3
Nucleotide bindingi40 – 46ATPUniRule annotation7

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotationSAAS annotationImported, Ligase
Biological processProtein biosynthesisUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciEELI515620:G1GMQ-489-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--tRNA ligaseUniRule annotation (EC:6.1.1.18UniRule annotation)
Alternative name(s):
Glutaminyl-tRNA synthetaseUniRule annotation
Short name:
GlnRSUniRule annotation
Gene namesi
Name:glnSUniRule annotation
Ordered Locus Names:EUBELI_00503Imported
OrganismiEubacterium eligens (strain ATCC 27750 / VPI C15-48)Imported
Taxonomic identifieri515620 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesEubacteriaceaeEubacterium
Proteomesi
  • UP000001476 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Monomer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi515620.EUBELI_00503

Structurei

3D structure databases

ProteinModelPortaliC4Z3P7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 340tRNA-synt_1cInterPro annotationAdd BLAST315
Domaini344 – 533tRNA-synt_1c_CInterPro annotationAdd BLAST190

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi33 – 43"HIGH" regionUniRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CX6 Bacteria
COG0008 LUCA
HOGENOMiHOG000259232
KOiK01886
OMAiVTHSICT
OrthoDBiPOG091H00G9

Family and domain databases

Gene3Di1.10.1160.10, 1 hit
2.40.240.10, 3 hits
3.40.50.620, 2 hits
HAMAPiMF_00126 Gln_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR004514 Gln-tRNA-synth
IPR022861 Gln_tRNA_ligase_bac
IPR000924 Glu/Gln-tRNA-synth
IPR020058 Glu/Gln-tRNA-synth_Ib_cat-dom
IPR020059 Glu/Gln-tRNA-synth_Ib_codon-bd
IPR020061 Glu_tRNA_lig_a-bdl
IPR020056 Rbsml_L25/Gln-tRNA_synth_N
IPR011035 Ribosomal_L25/Gln-tRNA_synth
IPR014729 Rossmann-like_a/b/a_fold
PfamiView protein in Pfam
PF00749 tRNA-synt_1c, 1 hit
PF03950 tRNA-synt_1c_C, 1 hit
PRINTSiPR00987 TRNASYNTHGLU
SUPFAMiSSF50715 SSF50715, 1 hit
TIGRFAMsiTIGR00440 glnS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

C4Z3P7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENEALSKNF IEQIIDKDIE SGHCKKVITR FPPEPNGYLH IGHAKSILLN
60 70 80 90 100
YGLAKEYGGQ FNMRFDDTNP TKEKVEFVDS IKADVEWLGA EWNGDVLFAS
110 120 130 140 150
DYFPQMYEAA VKLIKKGKAY VDDLSAEEIR QYRGTLTEPG KESPYRNRSV
160 170 180 190 200
EENLQLFEEM KEGKYADGTK VLRAKIDMAS PNINMRDPII YRVAHMTHHR
210 220 230 240 250
TGDQWCIYPM YDFAHPIEDA VEGITHSICT LEFEDHRPLY DWVVIETGYK
260 270 280 290 300
TSPEENPKQI EFAKLYLTNV VTGKRYIKKL VEDGIVDGWD DPRLVSIAAL
310 320 330 340 350
RRRGFTPEAI KMFVELVGVT KAQGSVEYPM LEYCIREDLK LKVKRMMAVL
360 370 380 390 400
DPVKLVIDNY PEGQVEYMEV ANNQENPEMG TRKVPFTKEL YIEREDFMEE
410 420 430 440 450
PPKKYFRLFP GNEVRLMNAY FVTCTDYVKD ENGKVIEVHC TYDPETKGGN
460 470 480 490 500
FTGRKVKGTI HWVSATEGCK AEVRLYENIV DEEKGVYNEE DGSMNINPNS
510 520 530 540 550
KTVLTECYLE PELMKAVSED KFQFVRNGYF CVDNKDSEPG KPIFNRIVSL

KSSFKLQK
Length:558
Mass (Da):64,393
Last modified:July 28, 2009 - v1
Checksum:i61E450B90DC623D5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001104 Genomic DNA Translation: ACR71516.1
RefSeqiWP_012738752.1, NC_012778.1

Genome annotation databases

EnsemblBacteriaiACR71516; ACR71516; EUBELI_00503
KEGGieel:EUBELI_00503

Similar proteinsi

Entry informationi

Entry nameiC4Z3P7_EUBE2
AccessioniPrimary (citable) accession number: C4Z3P7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: March 28, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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