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Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Eubacterium eligens (strain ATCC 27750 / VPI C15-48)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei274 – 2741ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glutamine-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutaminyl-tRNA aminoacylation Source: InterPro
  2. glutamyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetaseUniRule annotation, Ligase

Keywords - Biological processi

Protein biosynthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciEELI515620:GH1N-503-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--tRNA ligaseUniRule annotationSAAS annotation (EC:6.1.1.18UniRule annotationSAAS annotation)
Alternative name(s):
Glutaminyl-tRNA synthetaseUniRule annotation
Gene namesi
Name:glnSUniRule annotation
Ordered Locus Names:EUBELI_00503Imported
OrganismiEubacterium eligens (strain ATCC 27750 / VPI C15-48)Imported
Taxonomic identifieri515620 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesEubacteriaceaeEubacterium
ProteomesiUP000001476: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Monomer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi515620.EUBELI_00503.

Structurei

3D structure databases

ProteinModelPortaliC4Z3P7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi33 – 4311"HIGH" regionUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0008.
HOGENOMiHOG000259232.
KOiK01886.
OMAiVTHSICT.
OrthoDBiEOG6DRPF7.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPiMF_00126. Gln_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR10119. PTHR10119. 1 hit.
PfamiPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C4Z3P7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MENEALSKNF IEQIIDKDIE SGHCKKVITR FPPEPNGYLH IGHAKSILLN
60 70 80 90 100
YGLAKEYGGQ FNMRFDDTNP TKEKVEFVDS IKADVEWLGA EWNGDVLFAS
110 120 130 140 150
DYFPQMYEAA VKLIKKGKAY VDDLSAEEIR QYRGTLTEPG KESPYRNRSV
160 170 180 190 200
EENLQLFEEM KEGKYADGTK VLRAKIDMAS PNINMRDPII YRVAHMTHHR
210 220 230 240 250
TGDQWCIYPM YDFAHPIEDA VEGITHSICT LEFEDHRPLY DWVVIETGYK
260 270 280 290 300
TSPEENPKQI EFAKLYLTNV VTGKRYIKKL VEDGIVDGWD DPRLVSIAAL
310 320 330 340 350
RRRGFTPEAI KMFVELVGVT KAQGSVEYPM LEYCIREDLK LKVKRMMAVL
360 370 380 390 400
DPVKLVIDNY PEGQVEYMEV ANNQENPEMG TRKVPFTKEL YIEREDFMEE
410 420 430 440 450
PPKKYFRLFP GNEVRLMNAY FVTCTDYVKD ENGKVIEVHC TYDPETKGGN
460 470 480 490 500
FTGRKVKGTI HWVSATEGCK AEVRLYENIV DEEKGVYNEE DGSMNINPNS
510 520 530 540 550
KTVLTECYLE PELMKAVSED KFQFVRNGYF CVDNKDSEPG KPIFNRIVSL

KSSFKLQK
Length:558
Mass (Da):64,393
Last modified:July 28, 2009 - v1
Checksum:i61E450B90DC623D5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001104 Genomic DNA. Translation: ACR71516.1.
RefSeqiYP_002929963.1. NC_012778.1.

Genome annotation databases

EnsemblBacteriaiACR71516; ACR71516; EUBELI_00503.
GeneIDi7957615.
KEGGieel:EUBELI_00503.
PATRICi21864192. VBIEubEli113401_0461.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001104 Genomic DNA. Translation: ACR71516.1.
RefSeqiYP_002929963.1. NC_012778.1.

3D structure databases

ProteinModelPortaliC4Z3P7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi515620.EUBELI_00503.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACR71516; ACR71516; EUBELI_00503.
GeneIDi7957615.
KEGGieel:EUBELI_00503.
PATRICi21864192. VBIEubEli113401_0461.

Phylogenomic databases

eggNOGiCOG0008.
HOGENOMiHOG000259232.
KOiK01886.
OMAiVTHSICT.
OrthoDBiEOG6DRPF7.

Enzyme and pathway databases

BioCyciEELI515620:GH1N-503-MONOMER.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPiMF_00126. Gln_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR10119. PTHR10119. 1 hit.
PfamiPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27750 / VPI C15-48Imported.

Entry informationi

Entry nameiC4Z3P7_EUBE2
AccessioniPrimary (citable) accession number: C4Z3P7
Entry historyi
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: February 4, 2015
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.