C4Z2Y8 (C4Z2Y8_EUBE2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
3-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
EC=2.5.1.19 HAMAP MF_00210

Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase HAMAP MF_00210

Gene names

Name:	aroA HAMAP MF_00210
Ordered Locus Names:	EUBELI_00357

Organism

Eubacterium eligens (strain ATCC 27750 / VPI C15-48) [Complete proteome] [HAMAP] EMBL ACR71393.1

Taxonomic identifier

515620 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Eubacteriaceae › Eubacterium

Protein attributes

Sequence length	431 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210
Subunit structure	Monomer By similarity. HAMAP MF_00210
Subcellular location	Cytoplasm By similarity HAMAP MF_00210.
Sequence similarities	Belongs to the EPSP synthase family. HAMAP MF_00210

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00210
Cellular component	Cytoplasm HAMAP MF_00210
Molecular function	Transferase HAMAP MF_00210 EMBL ACR71393.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-phosphoshikimate 1-carboxyvinyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C4Z2Y8 [UniParc]. Last modified July 28, 2009. Version 1. Checksum: CD361A06FED2344F	FASTA	431	47,265
	10 20 30 40 50 60 MSQYKVKKLD HPIHCTVEVP GSKSITNRAL LMAALSQGEC TLKGVLFSDD SRHFLLSLIA 70 80 90 100 110 120 LGYIIEVNEV ERYVIIHGHG RDIPKKRATI NVGSAGTAAR FLTAMLALSD GEYTIEASEQ 130 140 150 160 170 180 MKKRPMLPLF EALQSMGAEI EFLEKDGHLP VNVKGAAYGG KKPQNHVSIS ISESTQFLSA 190 200 210 220 230 240 LMMTSPMLEE GIHVHITSNK TEGSYVRITA KMMEQFGCVV DHKGAEYVVP AGSGYYPQTY 250 260 270 280 290 300 YIEPDVSAAC YFYAAAALIG GTAIVKGVHS NSMQGDLKFI DVLKQMGCAV TEEREGICVS 310 320 330 340 350 360 GPKDGEYCGV DVDMNDFSDQ SMTLAAIAPF AKTTTVIKNI EHIRLQESDR IEAMVNELNN 370 380 390 400 410 420 LGVDVKEGRD RIEISPANVK PGVVDTYNDH RMAMSFALIG LRVDGIIIDN YECCCKTFEN 430 YFEVLEKACA Q

References

[1]

"Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla." Mahowald M.A., Rey F.E., Seedorf H., Turnbaugh P.J., Fulton R.S., Wollam A., Shah N., Wang C., Magrini V., Wilson R.K., Cantarel B.L., Coutinho P.M., Henrissat B., Crock L.W., Russell A., Verberkmoes N.C., Hettich R.L., Gordon J.I. Proc. Natl. Acad. Sci. U.S.A. 106:5859-5864(2009) [PubMed: 19321416] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001104 Genomic DNA. Translation: ACR71393.1.
RefSeq	YP_002929840.1. NC_012778.1.
3D structure databases
ProteinModelPortal	C4Z2Y8.
ModBase	Search...
Protein-protein interaction databases
STRING	C4Z2Y8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7958125.
GenomeReviews	Gene locus EUBELI_00357 in contig CP001104_GR.
KEGG	eel:EUBELI_00357.
PATRIC	21863906. VBIEubEli113401_0340.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	GADIEWG.
ProtClustDB	CLSK2548237.
Family and domain databases
HAMAP	MF_00210. EPSP_synth. [Tree]
InterPro	IPR001986. Enolpyruvate_Tfrase_dom. IPR006264. EPSP_synthase. IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b. [Graphical view]
Gene3D	G3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KO	K00800.
Pfam	PF00275. EPSP_synthase. 1 hit. [Graphical view]
PIRSF	PIRSF000505. EPSPS. 1 hit.
SUPFAM	SSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMs	TIGR01356. AroA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C4Z2Y8_EUBE2

Accession

Primary (citable) accession number: C4Z2Y8

Entry history

Integrated into UniProtKB/TrEMBL:	July 28, 2009
Last sequence update:	July 28, 2009
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)