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Protein

DNA replication and repair protein RecF

Gene

recF

Organism
Eubacterium eligens (strain ATCC 27750 / VPI C15-48)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi30 – 378ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA repair, DNA replication, SOS response

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciEELI515620:GH1N-4-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA replication and repair protein RecFUniRule annotation
Gene namesi
Name:recFUniRule annotation
Ordered Locus Names:EUBELI_00004
OrganismiEubacterium eligens (strain ATCC 27750 / VPI C15-48)
Taxonomic identifieri515620 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesEubacteriaceaeEubacterium
Proteomesi
  • UP000001476 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 363363DNA replication and repair protein RecFPRO_1000205482Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi515620.EUBELI_00004.

Family & Domainsi

Sequence similaritiesi

Belongs to the RecF family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C3X. Bacteria.
COG1195. LUCA.
HOGENOMiHOG000269559.
KOiK03629.
OMAiKVQTFIT.
OrthoDBiPOG091H00U7.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00365. RecF. 1 hit.
InterProiIPR001238. DNA-binding_RecF.
IPR018078. DNA-binding_RecF_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR32182:SF0. PTHR32182:SF0. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00611. recf. 1 hit.
PROSITEiPS00618. RECF_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C4Z176-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIVESVELKD FRNYEFLDMN FNEHVNIIYG DNAQGKTNIL ESIYMCSTSK
60 70 80 90 100
SHRGSKDREI VRFGEDESHI KLNVLKHGMK YRIDMHLKKN KTKGIAVNGI
110 120 130 140 150
PIKKAVELFG IINIVFFSPE DLNIIKNGPS ERRRFMDMEL SQLDKIYLSN
160 170 180 190 200
LVNYNKVLNQ RNKLLKDIAF SPSEQLMQTL DIWDMQLVKY GSLIIKGRKS
210 220 230 240 250
FIEKINTIIS DIHSRLTGGI ENIKVCYVPD VDVNDFEEEV RNSRQKDIKY
260 270 280 290 300
KVTGKGPHKD DLIFLINDND VRKYGSQGQQ RTAALSLKLS EIELVKLVIK
310 320 330 340 350
DTPVLLLDDV LSELDSNRQN FLINSIGDIQ TIVTCTGLEE FINNRMNINK
360
IFKVTDGHVV NEN
Length:363
Mass (Da):41,773
Last modified:July 28, 2009 - v1
Checksum:i5EC0E528F203F8B1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001104 Genomic DNA. Translation: ACR71050.1.
RefSeqiWP_012738288.1. NC_012778.1.

Genome annotation databases

EnsemblBacteriaiACR71050; ACR71050; EUBELI_00004.
KEGGieel:EUBELI_00004.
PATRICi21863214. VBIEubEli113401_0004.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001104 Genomic DNA. Translation: ACR71050.1.
RefSeqiWP_012738288.1. NC_012778.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi515620.EUBELI_00004.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACR71050; ACR71050; EUBELI_00004.
KEGGieel:EUBELI_00004.
PATRICi21863214. VBIEubEli113401_0004.

Phylogenomic databases

eggNOGiENOG4105C3X. Bacteria.
COG1195. LUCA.
HOGENOMiHOG000269559.
KOiK03629.
OMAiKVQTFIT.
OrthoDBiPOG091H00U7.

Enzyme and pathway databases

BioCyciEELI515620:GH1N-4-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00365. RecF. 1 hit.
InterProiIPR001238. DNA-binding_RecF.
IPR018078. DNA-binding_RecF_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR32182:SF0. PTHR32182:SF0. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00611. recf. 1 hit.
PROSITEiPS00618. RECF_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRECF_EUBE2
AccessioniPrimary (citable) accession number: C4Z176
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: September 7, 2016
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.