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Protein

Kinesin-like protein

Gene

CAWG_06014

Organism
Candida albicans (strain WO-1) (Yeast)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi452 – 4576ADPCombined sources

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. microtubule motor activity Source: InterPro

GO - Biological processi

  1. microtubule-based movement Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Motor proteinUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Kinesin-like proteinUniRule annotation
Gene namesi
ORF Names:CAWG_06014Imported
OrganismiCandida albicans (strain WO-1) (Yeast)Imported
Taxonomic identifieri294748 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
ProteomesiUP000001429: Chromosome 2, Supercontig 1.9

Subcellular locationi

GO - Cellular componenti

  1. kinesin complex Source: InterPro
  2. microtubule Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

MicrotubuleUniRule annotation

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4H1GX-ray2.15A351-694[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.UniRule annotation
Contains 1 kinesin motor domain.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000116164.
OMAiHANTHRS.
OrthoDBiEOG7RRFGF.

Family and domain databases

Gene3Di3.40.850.10. 1 hit.
InterProiIPR027640. Kinesin-like_fam.
IPR019821. Kinesin_motor_CS.
IPR001752. Kinesin_motor_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24115. PTHR24115. 1 hit.
PfamiPF00225. Kinesin. 1 hit.
[Graphical view]
PRINTSiPR00380. KINESINHEAVY.
SMARTiSM00129. KISc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00411. KINESIN_MOTOR_1. 1 hit.
PS50067. KINESIN_MOTOR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C4YKK8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANRAQVMSD ENTKHKFLNV SQPSNLLGGS SSSNSLRRPL NDNTVSVSNK
60 70 80 90 100
MRKTTSQIPV AKDTVPTLTI SESNRFRQLV NEKKIDLEQL KLNATTLRNE
110 120 130 140 150
LEKQTYENFT IQSNYQNLER ILNDLNLKIG ELNSYKQSSL DALIKNFELN
160 170 180 190 200
NHQLKMNHQE KLNNLKEDIT KQVDKILTEK QHKYEVEISN LNKEINKIKS
210 220 230 240 250
DRKNTESDLN RRLIQLKEDQ HKQELMMVGR VNDDINNMKK EIADINSLLE
260 270 280 290 300
SKTKQIELIK SVEIEGASNK VDKFTLLLDQ LTSKNKSKQE DIQALEKKVA
310 320 330 340 350
TTKESVKAIF EKSTARTSEV HRLQFEVGRM KTELVDQETK RRKLHAQLQD
360 370 380 390 400
LKGNIRVFCR IRNVSSSSSS SSSSSSEDII QYEAPQDIND ESKQELVITR
410 420 430 440 450
NINNNFSNLR FSFDKIFERE QSNDLVFEEL SQLIQCSLDG TNVCVFAYGQ
460 470 480 490 500
TGSGKTFTMS HPTNGMIPLS LKKIFNDIEE LKEKGWSYTV RGKFIEIYNE
510 520 530 540 550
AIVDLLNPKI DPNTKYEIKH DDIAGKTTVT NVSTIDIKSP EQAITILNQA
560 570 580 590 600
NKKRSTAATK SNDHSSRSHS IFIIDLQGYN SLTKESSYGT LNLIDLAGSE
610 620 630 640 650
RLNNSRAEGD RLKETQAINK SLSCLGDVIH SLNLKDGSHV PYRNSKLTYL
660 670 680 690
LKHSLGGNSK TLMFVNISPL TKDLNETINS LRFATKVNNA RINK
Length:694
Mass (Da):78,925
Last modified:July 28, 2009 - v1
Checksum:i561113221D874A8E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH672354 Genomic DNA. Translation: EEQ47437.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH672354 Genomic DNA. Translation: EEQ47437.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4H1GX-ray2.15A351-694[»]
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOGENOMiHOG000116164.
OMAiHANTHRS.
OrthoDBiEOG7RRFGF.

Family and domain databases

Gene3Di3.40.850.10. 1 hit.
InterProiIPR027640. Kinesin-like_fam.
IPR019821. Kinesin_motor_CS.
IPR001752. Kinesin_motor_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24115. PTHR24115. 1 hit.
PfamiPF00225. Kinesin. 1 hit.
[Graphical view]
PRINTSiPR00380. KINESINHEAVY.
SMARTiSM00129. KISc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00411. KINESIN_MOTOR_1. 1 hit.
PS50067. KINESIN_MOTOR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: WO-1Imported.
  2. "Crystal structure of the Candida albicans Kar3 kinesin motor domain fused to maltose-binding protein."
    Delorme C., Joshi M., Allingham J.S.
    Biochem. Biophys. Res. Commun. 428:427-432(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.15 ANGSTROMS) OF 351-694 IN COMPLEX WITH ADP.

Entry informationi

Entry nameiC4YKK8_CANAW
AccessioniPrimary (citable) accession number: C4YKK8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: March 4, 2015
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.