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C4Y9Q7

- C4Y9Q7_CLAL4

UniProt

C4Y9Q7 - C4Y9Q7_CLAL4

Protein

Malate dehydrogenase

Gene

CLUG_05128

Organism
Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (28 Jul 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    (S)-malate + NAD+ = oxaloacetate + NADH.

    GO - Molecular functioni

    1. L-malate dehydrogenase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cellular carbohydrate metabolic process Source: InterPro
    2. malate metabolic process Source: InterPro
    3. tricarboxylic acid cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotation

    Keywords - Biological processi

    Tricarboxylic acid cycleUniRule annotation

    Keywords - Ligandi

    NADUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Malate dehydrogenaseUniRule annotation (EC:1.1.1.37UniRule annotation)
    Gene namesi
    ORF Names:CLUG_05128Imported
    OrganismiClavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae)Imported
    Taxonomic identifieri306902 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesMetschnikowiaceaeClavispora
    ProteomesiUP000007703: Unassembled WGS sequence

    Structurei

    3D structure databases

    ProteinModelPortaliC4Y9Q7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the LDH/MDH superfamily. MDH type 1 family.UniRule annotation

    Phylogenomic databases

    KOiK00026.
    OrthoDBiEOG7GJ6Q7.

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    3.90.110.10. 1 hit.
    InterProiIPR001557. L-lactate/malate_DH.
    IPR022383. Lactate/malate_DH_C.
    IPR001236. Lactate/malate_DH_N.
    IPR015955. Lactate_DH/Glyco_Ohase_4_C.
    IPR001252. Malate_DH_AS.
    IPR010097. Malate_DH_type1.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PANTHERiPTHR11540. PTHR11540. 1 hit.
    PfamiPF02866. Ldh_1_C. 1 hit.
    PF00056. Ldh_1_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000102. Lac_mal_DH. 1 hit.
    SUPFAMiSSF56327. SSF56327. 1 hit.
    TIGRFAMsiTIGR01772. MDH_euk_gproteo. 1 hit.
    PROSITEiPS00068. MDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C4Y9Q7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVKVTVCGAA GGIGQPLSML LKLNPRVSRL ALYDIVNAVG VAADLSHINT    50
    PAVVTGHQPA AKNDSSALVE ALQDSDIVVI PAGVPRKPGM SRADLFNINA 100
    SIVRDLVAHA GRTCPNAAIL IISNPVNATV AIAAAVLKKL GVFNPRKLFG 150
    VTTLDSVRAE TFLAQILDVP PASLRGKISV VGGHSGDTIV PLVHFDRALE 200
    SKMKTVSASD YANFVHRVQY GGDEVVKAKI GAGSATLSMA YAGYRFASNV 250
    LASLVDAAEY SAVPDSAYIY LDGAAGGAEI ATTLQDTPFF SVPVHLKKGE 300
    VSSVVDPWHL VRTHEEKKMI AVALEGLEKS VSQGTNFVEG SKI 343
    Length:343
    Mass (Da):35,872
    Last modified:July 28, 2009 - v1
    Checksum:i0C174B42A59C1B92
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH408081 Genomic DNA. Translation: EEQ41000.1.
    RefSeqiXP_002615113.1. XM_002615067.1.

    Genome annotation databases

    GeneIDi8495697.
    KEGGiclu:CLUG_05128.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH408081 Genomic DNA. Translation: EEQ41000.1 .
    RefSeqi XP_002615113.1. XM_002615067.1.

    3D structure databases

    ProteinModelPortali C4Y9Q7.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 8495697.
    KEGGi clu:CLUG_05128.

    Phylogenomic databases

    KOi K00026.
    OrthoDBi EOG7GJ6Q7.

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    3.90.110.10. 1 hit.
    InterProi IPR001557. L-lactate/malate_DH.
    IPR022383. Lactate/malate_DH_C.
    IPR001236. Lactate/malate_DH_N.
    IPR015955. Lactate_DH/Glyco_Ohase_4_C.
    IPR001252. Malate_DH_AS.
    IPR010097. Malate_DH_type1.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    PANTHERi PTHR11540. PTHR11540. 1 hit.
    Pfami PF02866. Ldh_1_C. 1 hit.
    PF00056. Ldh_1_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000102. Lac_mal_DH. 1 hit.
    SUPFAMi SSF56327. SSF56327. 1 hit.
    TIGRFAMsi TIGR01772. MDH_euk_gproteo. 1 hit.
    PROSITEi PS00068. MDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 42720Imported.

    Entry informationi

    Entry nameiC4Y9Q7_CLAL4
    AccessioniPrimary (citable) accession number: C4Y9Q7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 28, 2009
    Last sequence update: July 28, 2009
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3