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Protein

Malate dehydrogenase

Gene

CLUG_05128

Organism
Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + NAD+ = oxaloacetate + NADH.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei184Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
Biological processTricarboxylic acid cycleUniRule annotation
LigandNADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Malate dehydrogenaseUniRule annotation (EC:1.1.1.37UniRule annotation)
Gene namesi
ORF Names:CLUG_05128Imported
OrganismiClavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae)Imported
Taxonomic identifieri306902 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesMetschnikowiaceaeClavispora
Proteomesi
  • UP000007703 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Interactioni

Protein-protein interaction databases

STRINGi306902.XP_002615113.1.

Structurei

3D structure databases

ProteinModelPortaliC4Y9Q7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 150Ldh_1_NInterPro annotationAdd BLAST149
Domaini152 – 338Ldh_1_CInterPro annotationAdd BLAST187

Sequence similaritiesi

Belongs to the LDH/MDH superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG1494. Eukaryota.
COG0039. LUCA.
InParanoidiC4Y9Q7.
KOiK00026.
OrthoDBiEOG092C34N7.

Family and domain databases

InterProiView protein in InterPro
IPR001557. L-lactate/malate_DH.
IPR022383. Lactate/malate_DH_C.
IPR001236. Lactate/malate_DH_N.
IPR001252. Malate_DH_AS.
IPR010097. Malate_DH_type1.
PfamiView protein in Pfam
PF02866. Ldh_1_C. 1 hit.
PF00056. Ldh_1_N. 1 hit.
PIRSFiPIRSF000102. Lac_mal_DH. 1 hit.
TIGRFAMsiTIGR01772. MDH_euk_gproteo. 1 hit.
PROSITEiView protein in PROSITE
PS00068. MDH. 1 hit.

Sequencei

Sequence statusi: Complete.

C4Y9Q7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVKVTVCGAA GGIGQPLSML LKLNPRVSRL ALYDIVNAVG VAADLSHINT
60 70 80 90 100
PAVVTGHQPA AKNDSSALVE ALQDSDIVVI PAGVPRKPGM SRADLFNINA
110 120 130 140 150
SIVRDLVAHA GRTCPNAAIL IISNPVNATV AIAAAVLKKL GVFNPRKLFG
160 170 180 190 200
VTTLDSVRAE TFLAQILDVP PASLRGKISV VGGHSGDTIV PLVHFDRALE
210 220 230 240 250
SKMKTVSASD YANFVHRVQY GGDEVVKAKI GAGSATLSMA YAGYRFASNV
260 270 280 290 300
LASLVDAAEY SAVPDSAYIY LDGAAGGAEI ATTLQDTPFF SVPVHLKKGE
310 320 330 340
VSSVVDPWHL VRTHEEKKMI AVALEGLEKS VSQGTNFVEG SKI
Length:343
Mass (Da):35,872
Last modified:July 28, 2009 - v1
Checksum:i0C174B42A59C1B92
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH408081 Genomic DNA. Translation: EEQ41000.1.
RefSeqiXP_002615113.1. XM_002615067.1.

Genome annotation databases

EnsemblFungiiEEQ41000; EEQ41000; CLUG_05128.
GeneIDi8495697.
KEGGiclu:CLUG_05128.

Similar proteinsi

Entry informationi

Entry nameiC4Y9Q7_CLAL4
AccessioniPrimary (citable) accession number: C4Y9Q7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: August 30, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported