C4XT58 (LFTR_DESMR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferase
EC=2.3.2.6

Alternative name(s):
L/F-transferase
Leucyltransferase
Phenyalanyltransferase

Gene names

Name:	aat
Ordered Locus Names:	DMR_23710

Organism

Desulfovibrio magneticus (strain ATCC 700980 / DSM 13731 / RS-1) [Complete proteome] [HAMAP]

Taxonomic identifier

573370 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Deltaproteobacteria › Desulfovibrionales › Desulfovibrionaceae › Desulfovibrio › Desulfovibrio magneticus

Protein attributes

Sequence length	247 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine By similarity. HAMAP-Rule MF_00688
Catalytic activity	L-leucyl-tRNA + protein = tRNA + L-leucyl-protein. HAMAP-Rule MF_00688 L-phenylalanyl-tRNA + protein = tRNA + L-phenylalanyl-protein. HAMAP-Rule MF_00688
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00688.
Sequence similarities	Belongs to the L/F-transferase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	protein catabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	leucyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 247	247	Leucyl/phenylalanyl-tRNA--protein transferase HAMAP-Rule MF_00688		PRO_1000212567

Sequences

	Sequence		Length	Mass (Da)
	C4XT58 [UniParc]. Last modified July 28, 2009. Version 1. Checksum: 461F1C7B1DEE0F37	FASTA	247	27,380
	10 20 30 40 50 60 MPVFALIDEP VFPSPHLAEP GGLLAVGGDL SVARLLAAYR RGIFPWYDDE SPILWWSPDP 70 80 90 100 110 120 RPILVPGHVR VSKRLERTIR SGKFTVTLDT DFAGVIRGCA AVPRDADNGT WIVPDMIEGY 130 140 150 160 170 180 ERLHAAGHAH SVEAWQNGEL VGGAYGVAIG KAFFGESMFH RATDASKVAF VTLCRFLDRH 190 200 210 220 230 240 EFRFIDCQQA TGHLLRFGAV QVRRNEFLRR LEAAREEEGM VGKWVLPRTT RCASPQPTSE SSPSAKQ

References

[1]

"Whole genome sequence of Desulfovibrio magneticus strain RS-1 revealed common gene clusters in magnetotactic bacteria." Nakazawa H., Arakaki A., Narita-Yamada S., Yashiro I., Jinno K., Aoki N., Tsuruyama A., Okamura Y., Tanikawa S., Fujita N., Takeyama H., Matsunaga T. Genome Res. 19:1801-1808(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700980 / DSM 13731 / RS-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP010904 Genomic DNA. Translation: BAH75862.1.
RefSeq	YP_002953748.1. NC_012796.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	573370.DMR_23710.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAH75862; BAH75862; DMR_23710.
GeneID	7982017.
KEGG	dma:DMR_23710.
PATRIC	21751037. VBIDesMag26496_2285.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2360.
HOGENOM	HOG000102325.
KO	K00684.
OMA	MFYGESM.
Enzyme and pathway databases
BioCyc	DMAG573370:GHJL-2397-MONOMER.
Family and domain databases
HAMAP	MF_00688. Leu_Phe_trans.
InterPro	IPR016181. Acyl_CoA_acyltransferase. IPR004616. Leu/Phe-tRNA_Trfase. [Graphical view]
Pfam	PF03588. Leu_Phe_trans. 1 hit. [Graphical view]
SUPFAM	SSF55729. Acyl_CoA_acyltransferase. 1 hit.
TIGRFAMs	TIGR00667. aat. 1 hit.
ProtoNet	Search...

Entry information

Entry name

LFTR_DESMR

Accession

Primary (citable) accession number: C4XT58

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	July 28, 2009
Last modified:	May 29, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program