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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Desulfovibrio magneticus (strain ATCC 700980 / DSM 13731 / RS-1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + [protein] = tRNA(Leu) + L-leucyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotation
Ordered Locus Names:DMR_23710
OrganismiDesulfovibrio magneticus (strain ATCC 700980 / DSM 13731 / RS-1)
Taxonomic identifieri573370 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio
Proteomesi
  • UP000009071 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002125671 – 247Leucyl/phenylalanyl-tRNA--protein transferaseAdd BLAST247

Interactioni

Protein-protein interaction databases

STRINGi573370.DMR_23710.

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108R4Z. Bacteria.
COG2360. LUCA.
HOGENOMiHOG000102325.
KOiK00684.
OMAiYRQGIFP.
OrthoDBiPOG091H045I.

Family and domain databases

HAMAPiMF_00688. Leu_Phe_trans. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view]
PfamiPF03588. Leu_Phe_trans. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
TIGRFAMsiTIGR00667. aat. 1 hit.

Sequencei

Sequence statusi: Complete.

C4XT58-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPVFALIDEP VFPSPHLAEP GGLLAVGGDL SVARLLAAYR RGIFPWYDDE
60 70 80 90 100
SPILWWSPDP RPILVPGHVR VSKRLERTIR SGKFTVTLDT DFAGVIRGCA
110 120 130 140 150
AVPRDADNGT WIVPDMIEGY ERLHAAGHAH SVEAWQNGEL VGGAYGVAIG
160 170 180 190 200
KAFFGESMFH RATDASKVAF VTLCRFLDRH EFRFIDCQQA TGHLLRFGAV
210 220 230 240
QVRRNEFLRR LEAAREEEGM VGKWVLPRTT RCASPQPTSE SSPSAKQ
Length:247
Mass (Da):27,380
Last modified:July 28, 2009 - v1
Checksum:i461F1C7B1DEE0F37
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP010904 Genomic DNA. Translation: BAH75862.1.
RefSeqiWP_015861043.1. NC_012796.1.

Genome annotation databases

EnsemblBacteriaiBAH75862; BAH75862; DMR_23710.
KEGGidma:DMR_23710.
PATRICi21751037. VBIDesMag26496_2285.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP010904 Genomic DNA. Translation: BAH75862.1.
RefSeqiWP_015861043.1. NC_012796.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi573370.DMR_23710.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAH75862; BAH75862; DMR_23710.
KEGGidma:DMR_23710.
PATRICi21751037. VBIDesMag26496_2285.

Phylogenomic databases

eggNOGiENOG4108R4Z. Bacteria.
COG2360. LUCA.
HOGENOMiHOG000102325.
KOiK00684.
OMAiYRQGIFP.
OrthoDBiPOG091H045I.

Family and domain databases

HAMAPiMF_00688. Leu_Phe_trans. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view]
PfamiPF03588. Leu_Phe_trans. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
TIGRFAMsiTIGR00667. aat. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiLFTR_DESMR
AccessioniPrimary (citable) accession number: C4XT58
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: November 2, 2016
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.