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C4X6U4 (C4X6U4_KLEPN) Unreviewed, UniProtKB/TrEMBL

Last modified November 13, 2013. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length416 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
C4X6U4 [UniParc].

Last modified July 28, 2009. Version 1.
Checksum: 01132AB90538A89A

FASTA41645,749
        10         20         30         40         50         60 
MESKVVVPAE GQKITLQNGK LNVPHNPIIP FIEGDGIGVD VTPAMLKVVD AAVEKAYKGE 

        70         80         90        100        110        120 
RKISWMEVYT GEKSTHVYGQ DVWLPAETLD LIRDYRVAIK GPLTTPVGGG IRSLNVALRQ 

       130        140        150        160        170        180 
ELDLYVCLRP VRYYQGTPSP VKHPELTDMV IFRENSEDIY AGIEWKADSA EADKVIKFLR 

       190        200        210        220        230        240 
DEMGVKKIRF PEHCGIGIKP CSEEGTKRLV RAAIEYAITN DRDSVTLVHK GNIMKFTEGA 

       250        260        270        280        290        300 
FKDWGYQLAR EEFGGELIDG GPWVKIKNPN TGKEIVVKDV IADAFLQQIL LRPAEYDVIA 

       310        320        330        340        350        360 
CMNLNGDYIS DALAAQVGGI GIAPGANIGD ECALFEATHG TAPKYAGQDK VNPGSIILSA 

       370        380        390        400        410 
EMMLRHMQWF EAADLIVKGM EGAIAAKTVT YDFERLMEGA KLLKCSEFGD AIIANM 

« Hide

References

[1]Wu K.M., Tsai S.F.
Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NTUH-K2044 EMBL BAH62852.1.
[2]"Genome sequencing and comparative analysis of Klebsiella pneumoniae NTUH-K2044, a strain causing liver abscess and meningitis."
Wu K.-M., Li L.-H., Yan J.-J., Tsao N., Liao T.-L., Tsai H.-C., Fung C.-P., Chen H.-J., Liu Y.-M., Wang J.-T., Fang C.-T., Chang S.-C., Shu H.-Y., Liu T.-T., Chen Y.-T., Shiau Y.-R., Lauderdale T.-L., Su I.-J., Kirby R., Tsai S.-F.
J. Bacteriol. 191:4492-4501(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NTUH-K2044 EMBL BAH62852.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP006725 Genomic DNA. Translation: BAH62852.1.
RefSeqYP_002918919.1. NC_012731.1.

3D structure databases

ProteinModelPortalC4X6U4.
SMRC4X6U4. Positions 1-416.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING484021.KP1_2146.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAH62852; BAH62852; KP1_2146.
GeneID7949498.
KEGGkpu:KP1_2146.
PATRIC20448136. VBIKlePne21779_1885.

Phylogenomic databases

eggNOGCOG0538.
KOK00031.
OrthoDBEOG6SNDTP.
ProtClustDBPRK07006.

Enzyme and pathway databases

BioCycKPNE484021:GCWL-1996-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC4X6U4_KLEPN
AccessionPrimary (citable) accession number: C4X6U4
Entry history
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: November 13, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)