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C4WZN3 (C4WZN3_KLEPN) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
N-acetyl-gamma-glutamyl-phosphate reductase HAMAP-Rule MF_00150
Short name=AGPR HAMAP-Rule MF_00150
EC=1.2.1.38 HAMAP-Rule MF_00150
Alternative name(s):
N-acetyl-glutamate semialdehyde dehydrogenase HAMAP-Rule MF_00150
Gene names
Name:argC HAMAP-Rule MF_00150 EMBL BAH61022.1
ORF Names:KP1_0110 EMBL BAH61022.1
OrganismKlebsiella pneumoniae subsp. pneumoniae NTUH-K2044 EMBL BAH61022.1
Taxonomic identifier484021 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Klebsiella ›

Protein attributes

Sequence length334 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH. HAMAP-Rule MF_00150 SAAS SAAS023013

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4. HAMAP-Rule MF_00150 SAAS SAAS023013

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00150 SAAS SAAS023013.

Sequence similarities

Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. HAMAP-Rule MF_00150

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1541 By similarity HAMAP-Rule MF_00150

Sequences

Sequence LengthMass (Da)Tools
C4WZN3 [UniParc].

Last modified July 28, 2009. Version 1.
Checksum: D958265DDFC0162A

FASTA33435,874
        10         20         30         40         50         60 
MLNTLIVGAS GYAGAELVTY INRHPHMNIT ALTVSAQSND AGKLISDLHP QLKGIVDMPL 

        70         80         90        100        110        120 
QPMSDISEFS AGVDVVFLAT AHEVSHDLAP QFLAAGCVVF DLSGAFRVND GAFYEKYYGF 

       130        140        150        160        170        180 
THRHPDLLKQ AVYGLAEWSA DALKDAQLIA VPGCYPTAAQ LSLKPLIEAN LLDLNQWPVI 

       190        200        210        220        230        240 
NATSGVSGAG RKVAIGNSFC EVSLQPYGIF NHRHQPEIAS HLGAKVIFTP HLGNFKRGIL 

       250        260        270        280        290        300 
ETITCRLKPG VGHTQIAAVY QQAYADKPLV RLYDKGVPAL KSVEGLPFCD IGFAVQDDHL 

       310        320        330 
IVVAAEDNLL KGAAAQAVQC ANIRFGFAET QSLI

« Hide

References

[1]Wu K.M., Tsai S.F.
Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NTUH-K2044 EMBL BAH61022.1.
[2]"Genome sequencing and comparative analysis of Klebsiella pneumoniae NTUH-K2044, a strain causing liver abscess and meningitis."
Wu K.-M., Li L.-H., Yan J.-J., Tsao N., Liao T.-L., Tsai H.-C., Fung C.-P., Chen H.-J., Liu Y.-M., Wang J.-T., Fang C.-T., Chang S.-C., Shu H.-Y., Liu T.-T., Chen Y.-T., Shiau Y.-R., Lauderdale T.-L., Su I.-J., Kirby R., Tsai S.-F.
J. Bacteriol. 191:4492-4501(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NTUH-K2044 EMBL BAH61022.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP006725 Genomic DNA. Translation: BAH61022.1.
RefSeqYP_002917089.1. NC_012731.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING484021.KP1_0110.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAH61022; BAH61022; KP1_0110.
GeneID7946925.
KEGGkpu:KP1_0110.
PATRIC20444435. VBIKlePne21779_0099.

Phylogenomic databases

eggNOGCOG0002.
KOK00145.
ProtClustDBPRK00436.

Enzyme and pathway databases

UniPathwayUPA00068; UER00108.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
HAMAPMF_00150. ArgC_type1.
InterProIPR023013. AGPR_AS.
IPR000706. AGPR_type-1.
IPR016040. NAD(P)-bd_dom.
IPR000534. Semialdehyde_DH_NAD-bd.
IPR012280. Semialdhyde_DH_dimer_dom.
[Graphical view]
PfamPF01118. Semialdhyde_dh. 1 hit.
PF02774. Semialdhyde_dhC. 1 hit.
[Graphical view]
SMARTSM00859. Semialdhyde_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR01850. argC. 1 hit.
PROSITEPS01224. ARGC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC4WZN3_KLEPN
AccessionPrimary (citable) accession number: C4WZN3
Entry history
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: April 3, 2013
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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