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C4WZM0

- C4WZM0_KLEPN

UniProt

C4WZM0 - C4WZM0_KLEPN

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Protein
Submitted name:

Bifunctional aspartate kinase II/homoserine dehydrogenase II

Gene

metL

Organism
Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. aspartate kinase activity Source: InterPro
  2. homoserine dehydrogenase activity Source: InterPro
  3. NADP binding Source: InterPro

GO - Biological processi

  1. aspartate family amino acid biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Enzyme and pathway databases

BioCyciKPNE484021:GCWL-90-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Bifunctional aspartate kinase II/homoserine dehydrogenase IIImported
Gene namesi
Name:metLImported
ORF Names:KP1_0096Imported
OrganismiKlebsiella pneumoniae subsp. pneumoniae NTUH-K2044Imported
Taxonomic identifieri484021 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000010106: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi484021.KP1_0096.

Structurei

3D structure databases

ProteinModelPortaliC4WZM0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0527.
KOiK12525.
OrthoDBiEOG6M0T34.

Family and domain databases

Gene3Di3.40.1160.10. 2 hits.
3.40.50.720. 1 hit.
InterProiIPR001048. Asp/Glu/Uridylate_kinase.
IPR005106. Asp/hSer_DH_NAD-bd.
IPR001341. Asp_kinase_dom.
IPR018042. Aspartate_kinase_CS.
IPR011147. Bifunc_aspartokin/hSer_DH.
IPR001342. HDH_cat.
IPR019811. HDH_CS.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00696. AA_kinase. 1 hit.
PF00742. Homoserine_dh. 1 hit.
PF03447. NAD_binding_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000727. ThrA. 1 hit.
SUPFAMiSSF53633. SSF53633. 1 hit.
TIGRFAMsiTIGR00657. asp_kinases. 1 hit.
PROSITEiPS00324. ASPARTOKINASE. 1 hit.
PS01042. HOMOSER_DHGENASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C4WZM0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSVIAQAGAK GRQLHKFGGS SLADAKCYLR VAGIMKEYSQ AGDMMVVSAA
60 70 80 90 100
GSTTNQLISW LKLSQSDRLA AHQVQQSLRR YHTELIGGLL EPAAADTLIA
110 120 130 140 150
AFIHDLERLA GLLDGGVSEA VYAEVVGHGE VWSARLMAAV LNQLGMEAAW
160 170 180 190 200
LDARAFLRAE RAAQPQVDEG LSYPLLQQLM AQHPNKRLVV TGFISRNQAG
210 220 230 240 250
ETVLLGRNGS DYSATQIGAL AGASRVTIWS DVAGVYSADP RKVKDACLLP
260 270 280 290 300
LLRLDEASEL ARLAAPVLHA RTLQPVSASD IDLQLRCSYT PEQGSTRIER
310 320 330 340 350
VLASGTGARI VTSHDDVCLV EFQVPAGHDF KLAHKELDAL LKRAQLRPLA
360 370 380 390 400
VGVHADRKLL QFCYTSEVAD SALKLLDEAG LPGELRLRQK LALVAMVGAG
410 420 430 440 450
VTRNPLHCHR FWQQLKGQPV EFTWQSEEGI SLVAVLRAGP TESLIQGLHQ
460 470 480 490 500
SLFRAEKRIG LMLFGKGNIG SRWLELFARE QTTLSARTGF EFILAGVVDS
510 520 530 540 550
KRSLLNYDGL DASRALAFFN DEAVEQDEES LFLWMRAHPY DDLVVLDVTA
560 570 580 590 600
SEQLADQYLD FASHGFHVIS ANKLAGASSS DKYRQIHDAF EKTGRHWLYN
610 620 630 640 650
ATVGAGLPVN HTVRDLIDSG DTILGLSGIF SGTLSWLFLQ FDGTVPFTDL
660 670 680 690 700
VDQAWQQGLT EPDPRVDLSG KDVMRKLVIL AREAGYDIEP DQVRVESLVP
710 720 730 740 750
AHCEEGSVDH FFENGEELNE QMLQRLEAAR EMGLVLRYVA RFDANGKARV
760 770 780 790 800
GVEAVREEHP LAALLPCDNV FAIESRWYRD NPLVIRGPGA GRDVTAGAIQ
810
SDINRLAQLL
Length:810
Mass (Da):88,714
Last modified:July 28, 2009 - v1
Checksum:iC1043E9F6A738F9C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP006725 Genomic DNA. Translation: BAH61009.1.
RefSeqiYP_002917076.1. NC_012731.1.

Genome annotation databases

EnsemblBacteriaiBAH61009; BAH61009; KP1_0096.
GeneIDi7947865.
KEGGikpu:KP1_0096.
PATRICi20444409. VBIKlePne21779_0086.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP006725 Genomic DNA. Translation: BAH61009.1 .
RefSeqi YP_002917076.1. NC_012731.1.

3D structure databases

ProteinModelPortali C4WZM0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 484021.KP1_0096.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAH61009 ; BAH61009 ; KP1_0096 .
GeneIDi 7947865.
KEGGi kpu:KP1_0096.
PATRICi 20444409. VBIKlePne21779_0086.

Phylogenomic databases

eggNOGi COG0527.
KOi K12525.
OrthoDBi EOG6M0T34.

Enzyme and pathway databases

BioCyci KPNE484021:GCWL-90-MONOMER.

Family and domain databases

Gene3Di 3.40.1160.10. 2 hits.
3.40.50.720. 1 hit.
InterProi IPR001048. Asp/Glu/Uridylate_kinase.
IPR005106. Asp/hSer_DH_NAD-bd.
IPR001341. Asp_kinase_dom.
IPR018042. Aspartate_kinase_CS.
IPR011147. Bifunc_aspartokin/hSer_DH.
IPR001342. HDH_cat.
IPR019811. HDH_CS.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
Pfami PF00696. AA_kinase. 1 hit.
PF00742. Homoserine_dh. 1 hit.
PF03447. NAD_binding_3. 1 hit.
[Graphical view ]
PIRSFi PIRSF000727. ThrA. 1 hit.
SUPFAMi SSF53633. SSF53633. 1 hit.
TIGRFAMsi TIGR00657. asp_kinases. 1 hit.
PROSITEi PS00324. ASPARTOKINASE. 1 hit.
PS01042. HOMOSER_DHGENASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequencing and comparative analysis of Klebsiella pneumoniae NTUH-K2044, a strain causing liver abscess and meningitis."
    Wu K.-M., Li L.-H., Yan J.-J., Tsao N., Liao T.-L., Tsai H.-C., Fung C.-P., Chen H.-J., Liu Y.-M., Wang J.-T., Fang C.-T., Chang S.-C., Shu H.-Y., Liu T.-T., Chen Y.-T., Shiau Y.-R., Lauderdale T.-L., Su I.-J., Kirby R., Tsai S.-F.
    J. Bacteriol. 191:4492-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NTUH-K2044Imported.

Entry informationi

Entry nameiC4WZM0_KLEPN
AccessioniPrimary (citable) accession number: C4WZM0
Entry historyi
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: October 1, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3