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Protein

Superoxide dismutase [Cu-Zn]

Gene

ACYPI003921

Organism
Acyrthosiphon pisum (Pea aphid)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • Cu cationUniRule annotationNote: Binds 1 copper ion per subunit.UniRule annotation
  • Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandCopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Name:ACYPI003921Imported
Synonyms:LOC100162795Imported
OrganismiAcyrthosiphon pisum (Pea aphid)Imported
Taxonomic identifieri7029 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraHemipteraSternorrhynchaAphidomorphaAphidoideaAphididaeMacrosiphiniAcyrthosiphon
Proteomesi
  • UP000007819 Componenti: Unassembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501456900622 – 217Superoxide dismutase [Cu-Zn]Sequence analysisAdd BLAST196

Interactioni

Protein-protein interaction databases

STRINGi7029.ACYPI003921-PA

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini38 – 176Sod_CuInterPro annotationAdd BLAST139

Sequence similaritiesi

Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0441 Eukaryota
COG2032 LUCA
HOGENOMiHOG000263447
KOiK04565
OMAiHIHEATE

Family and domain databases

CDDicd00305 Cu-Zn_Superoxide_Dismutase, 1 hit
Gene3Di2.60.40.200, 1 hit
InterProiView protein in InterPro
IPR036423 SOD-like_Cu/Zn_dom_sf
IPR024134 SOD_Cu/Zn_/chaperone
IPR018152 SOD_Cu/Zn_BS
IPR001424 SOD_Cu_Zn_dom
PANTHERiPTHR10003 PTHR10003, 1 hit
PfamiView protein in Pfam
PF00080 Sod_Cu, 1 hit
PRINTSiPR00068 CUZNDISMTASE
SUPFAMiSSF49329 SSF49329, 1 hit
PROSITEiView protein in PROSITE
PS00087 SOD_CU_ZN_1, 1 hit
PS00332 SOD_CU_ZN_2, 1 hit

Sequencei

Sequence statusi: Complete.

C4WTR6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPKIMLLIT LSVASAVLVS AASPPFQERK AIVVLKGPGQ VSGNVTFIQA
60 70 80 90 100
NRGGPVMITG VVSGLTEGPH GFHVHEKGDV TNGCISTGSH FNPQGNKHGG
110 120 130 140 150
PNDETRHAGD LGNIQADNTG VAQFSYSDSL ISLVGAHNIL GRAVVVHADT
160 170 180 190 200
DDMGRGGFTD SLTTGHAGSR VACGVIGILD PITPWDKSAG HRSPSTSHVL
210
LLTAVAAIAS MLAANSI
Length:217
Mass (Da):22,140
Last modified:July 28, 2009 - v1
Checksum:i88946D2ED0468E95
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABLF02025899 Genomic DNA No translation available.
AK340739 mRNA Translation: BAH71286.1
RefSeqiNP_001156153.1, NM_001162681.2
UniGeneiAps.50476
Aps.52325
Aps.752

Genome annotation databases

EnsemblMetazoaiACYPI003921-RA; ACYPI003921-PA; ACYPI003921
GeneIDi100162795
KEGGiapi:100162795

Similar proteinsi

Entry informationi

Entry nameiC4WTR6_ACYPI
AccessioniPrimary (citable) accession number: C4WTR6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: May 23, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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