C4WRV2 (C4WRV2_ACYPI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Superoxide dismutase [Cu-Zn] RuleBase RU000393
EC=1.15.1.1 RuleBase RU000393

Gene names

Name:	ACYPI007471 EMBL BAH70622.1
Synonyms:	XM_001950906.1 EnsemblMetazoa ACYPI007471-PA

Organism

Acyrthosiphon pisum (Pea aphid) [Complete proteome] EMBL BAH70622.1

Taxonomic identifier

7029 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Paraneoptera › Hemiptera › Sternorrhyncha › Aphidiformes › Aphidomorpha › Aphidoidea › Aphididae › Aphidinae › Macrosiphini › Acyrthosiphon

Protein attributes

Sequence length	152 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity. RuleBase RU000393
Catalytic activity	2 superoxide + 2 H+ = O2 + H2O2. RuleBase RU000393
Cofactor	Binds 1 copper ion per subunit By similarity. RuleBase RU000393 Binds 1 zinc ion per subunit By similarity. RuleBase RU000393
Sequence similarities	Belongs to the Cu-Zn superoxide dismutase family. RuleBase RU000393

Ontologies

Keywords
Ligand	Copper RuleBase RU000393 Metal-binding RuleBase RU000393 Zinc RuleBase RU000393
Molecular function	Oxidoreductase RuleBase RU000393
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	superoxide metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW superoxide dismutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C4WRV2 [UniParc]. Last modified July 28, 2009. Version 1. Checksum: C0AE91BC453BBF18	FASTA	152	15,840
	10 20 30 40 50 60 MVKAVCVLNG EDVKGTIFFS QPDDKSPVEI TGELTGLSKG RHGFHIHEFG DNTNGCMSSG 70 80 90 100 110 120 PHFNPFGKTH GAPNDDVRHV GDLGNIEAPG SSVTKIQFND PIISLTGPLN IIGRTLVVHA 130 140 150 DQDDLGKGGH ELSATTGNAG ARIACGVIGI TK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A full-length cDNA resource of the pea aphid, Acyrthosiphon pisum." Shigenobu S., Nakabachi A., Richards S. Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: LSR1 EMBL BAH70622.1. Tissue: Whole body EMBL BAH70622.1.
[2]	Jiang H., Abraham K., Ali S., Alsbrooks S.L., Anim B.N., Anosike U.S., Attaway T., Bandaranaike D.P., Battles P.K., Bell S.N., Bell A.V., Beltran B., Bickham C., Bustamante Y., Caleb T., Canada A., Cardenas V., Carter K. , Chacko J., Chandrabose M.N., Chavez D., Chavez A., Chen L., Chu H.-S., Claassen K.J., Cockrell R., Collins M., Cooper J.A., Cree A., Curry S.M., Da Y., Dao M.D., Das B., Davila M.-L., Davy-Carroll L., Denson S., Dinh H., Ebong V.E., Edwards J.R., Egan A., El-Daye J., Escobedo L., Fernandez S., Fernando P.R., Flagg N., Forbes L.D., Fowler R.G., Fu Q., Gabisi R.A., Ganer J., Garbino Pronczuk A., Garcia R.M., Garner T., Garrett T.E., Gonzalez D.A., Hamid H., Hawkins E.S., Hirani K., Hogues M.E., Hollins B., Hsiao C.-H., Jabil R., James M.L., Jhangiani S.N., Johnson B., Johnson Q., Joshi V., Kalu J.B., Kam C., Kashfia A., Keebler J., Kisamo H., Kovar C.L., Lago L.A., Lai C.-Y., Laidlaw J., Lara F., Le T.-K., Lee S.L., Legall F.H., Lemon S.J., Lewis L.R., Li B., Liu Y., Liu Y.-S., Lopez J., Lozado R.J., Lu J., Madu R.C., Maheshwari M., Maheshwari R., Malloy K., Martinez E., Mathew T., Mercado I.C., Mercado C., Meyer B., Montgomery K., Morgan M.B., Munidasa M., Nazareth L.V., Nelson J., Ng B.M., Nguyen N.B., Nguyen P.Q., Nguyen T., Obregon M., Okwuonu G.O., Onwere C.G., Orozco G., Parra A., Patel S., Patil S., Perez A., Perez Y., Pham C., Primus E.L., Pu L.-L., Puazo M., Qin X., Quiroz J.B., Reese J., Richards S., Rives C.M., Robberts R., Ruiz S.J., Ruiz M.J., Santibanez J., Schneider B.W., Sisson I., Smith M., Sodergren E., Song X.-Z., Song B.B., Summersgill H., Thelus R., Thornton R.D., Trejos Z.Y., Usmani K., Vattathil S., Villasana D., Walker D.L., Wang S., Wang K., White C.S., Williams A.C., Williamson J., Wilson K., Woghiren I.O., Woodworth J.R., Worley K.C., Wright R.A., Wu W., Young L., Zhang L., Zhang J., Zhu Y., Muzny D.M., Weinstock G., Gibbs R.A. Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	EnsemblMetazoa Submitted (SEP-2012) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK339927 mRNA. Translation: BAH70622.1.
RefSeq	NP_001156243.1. NM_001162771.1.
UniGene	Aps.309.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	ACYPI007471-RA; ACYPI007471-PA; ACYPI007471.
GeneID	100166614.
KEGG	api:100166614.
Phylogenomic databases
HOGENOM	HOG000263447.
KO	K04565.
OMA	APRFESS.
OrthoDB	EOG43TXBZ.
Family and domain databases
Gene3D	2.60.40.200. 1 hit.
InterPro	IPR024134. SOD_Cu/Zn_/chaperones. IPR018152. SOD_Cu/Zn_BS. IPR001424. SOD_Cu_Zn_dom. [Graphical view]
PANTHER	PTHR10003. PTHR10003. 1 hit.
Pfam	PF00080. Sod_Cu. 1 hit. [Graphical view]
PRINTS	PR00068. CUZNDISMTASE.
SUPFAM	SSF49329. SOD_Cu_Zn. 1 hit.
PROSITE	PS00087. SOD_CU_ZN_1. 1 hit. PS00332. SOD_CU_ZN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C4WRV2_ACYPI

Accession

Primary (citable) accession number: C4WRV2

Entry history

Integrated into UniProtKB/TrEMBL:	July 28, 2009
Last sequence update:	July 28, 2009
Last modified:	April 3, 2013
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)