SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

C4V8Q1

- SYIC_NOSCE

UniProt

C4V8Q1 - SYIC_NOSCE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Probable isoleucine--tRNA ligase, cytoplasmic
Gene
NCER_100885
Organism
Nosema ceranae (strain BRL01) (Microsporidian parasite)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei618 – 6181ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. aminoacyl-tRNA editing activity Source: InterPro
  3. isoleucine-tRNA ligase activity Source: UniProtKB-EC

GO - Biological processi

  1. isoleucyl-tRNA aminoacylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable isoleucine--tRNA ligase, cytoplasmic (EC:6.1.1.5)
Alternative name(s):
Isoleucyl-tRNA synthetase
Short name:
IleRS
Gene namesi
ORF Names:NCER_100885
OrganismiNosema ceranae (strain BRL01) (Microsporidian parasite)
Taxonomic identifieri578460 [NCBI]
Taxonomic lineageiEukaryotaFungiMicrosporidiaNosematidaeNosema
ProteomesiUP000009082: Unassembled WGS sequence

Organism-specific databases

EuPathDBiMicrosporidiaDB:NCER_100885.

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10461046Probable isoleucine--tRNA ligase, cytoplasmic
PRO_0000388380Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliC4V8Q1.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi46 – 5611"HIGH" region By similarity
Add
BLAST
Motifi615 – 6195"KMSKS" region By similarity

Sequence similaritiesi

Phylogenomic databases

KOiK01870.
OrthoDBiEOG7FNCGS.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.40.50.620. 2 hits.
3.90.740.10. 1 hit.
InterProiIPR002300. aa-tRNA-synth_Ia.
IPR002301. Ile-tRNA-ligase.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view]
PfamiPF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 1 hit.
[Graphical view]
PRINTSiPR00984. TRNASYNTHILE.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsiTIGR00392. ileS. 1 hit.

Sequencei

Sequence statusi: Complete.

C4V8Q1-1 [UniParc]FASTAAdd to Basket

« Hide

MKFDSNLSIN DIETKILKFW KDTKCFKKSN ELSKNKKKYT FYDGPPFATG     50
LPHFGHILAG TVKDVITRYQ YQHNKRVDRR FGWDCHGLPV EFEIDKNLGI 100
SVKQEILEMG IDKYNAECKS IVMKHSSEWK DTVEKMGRWV DFDNSYKTMD 150
LSFMTSVWYV FSQLYKKGYV YRGYRVMPFS TGCMTTLSSS EAKSNYKMVN 200
DLSVVVEFPL KSKLFDKKVS ILAWTTTPWT LPSNCGLVVN KDFDYQIFEI 250
DHKFYCMLPN RIQDFNKKEV ILHELFKGEL LIGLEYEQPF NYFEEYRRCG 300
FFKIIGGSFV SSTDGTGIVH AAPAFGEDDY NCFVENNLIK QNDLVPCPVD 350
ENGKFTAEVF DYKGIYVKDA DKLIIKHLKE KIFCVKQISH NYPFCWRSEK 400
PLIYRLVSSW FIKVSDSVDK LIKNNEIINW VPKDIKHKKF GKWLSNAKDW 450
AFSRSRFWGT PIPLWVSDDY SEILCVESAE ELEKLSGKKI TDLHMEFIDD 500
IILTKNGKTL RRIPEVFDCW FESGCMPYAQ HSWPFRKVDN LNCEEIRHHF 550
HDSDNTLVYE NKILENFPAD FIGEGIDQTR GWFYTLHVIS TLLFDKPAFK 600
NVIVNGIVLA ENGKKMSKKD KNYPDPNIVM KTFGADSLRM YLISSPVVEA 650
DNLLFKEDGV KDVSKLLIIP WMNVLKFYTT SLQKRNDCEK LELDNWINYT 700
FNEFLSSVSN YMNNYQLSKV CGLAYKFLDN LSNWYLRIHR EEIRSGNTKI 750
LFNILKKFSV IMSPFAPFFS EYSFQCLLSS QQNEKSNSIN SVHFQMYPEA 800
QDSGDNSFEN AKDIIDAIRY LRDKHTISLK TPLKEVKIIS DELFMKDAAK 850
FSNTIIRECH VFNLIFVKES EVPELKIEYK AKPCFEYLKK DLKTMNDKIK 900
IINKLTQSEI RDLAFLDLSE EKYNVKRENI LIEKKATFPT GLCFASNKFV 950
ILVDNTIDDN VLEKKLAREF NSFIQKLRKS CGLKMNDTVN VEVDSEKIKQ 1000
ITKKFYPINF STEGQIVSPI DSDAQIDVFS YEGQELKVIL RLNKFL 1046
Length:1,046
Mass (Da):122,145
Last modified:July 28, 2009 - v1
Checksum:iB2FCC7669CD0CEF7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
ACOL01000062 Genomic DNA. Translation: EEQ82400.1.
RefSeqiXP_002996071.1. XM_002996025.1.

Genome annotation databases

GeneIDi9422100.
KEGGince:NCER_100885.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
ACOL01000062 Genomic DNA. Translation: EEQ82400.1 .
RefSeqi XP_002996071.1. XM_002996025.1.

3D structure databases

ProteinModelPortali C4V8Q1.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 9422100.
KEGGi nce:NCER_100885.

Organism-specific databases

EuPathDBi MicrosporidiaDB:NCER_100885.

Phylogenomic databases

KOi K01870.
OrthoDBi EOG7FNCGS.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.40.50.620. 2 hits.
3.90.740.10. 1 hit.
InterProi IPR002300. aa-tRNA-synth_Ia.
IPR002301. Ile-tRNA-ligase.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view ]
Pfami PF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 1 hit.
[Graphical view ]
PRINTSi PR00984. TRNASYNTHILE.
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsi TIGR00392. ileS. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genomic analyses of the microsporidian Nosema ceranae, an emergent pathogen of honey bees."
    Cornman R.S., Chen Y.P., Schatz M.C., Street C., Zhao Y., Desany B., Egholm M., Hutchison S., Pettis J.S., Lipkin W.I., Evans J.D.
    PLoS Pathog. 5:E1000466-E1000466(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BRL01.

Entry informationi

Entry nameiSYIC_NOSCE
AccessioniPrimary (citable) accession number: C4V8Q1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: July 28, 2009
Last modified: April 16, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi