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Protein

Probable eukaryotic translation initiation factor 4 gamma homolog

Gene

EIF4G

Organism
Nosema ceranae (strain BRL01) (Microsporidian parasite)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionInitiation factor, RNA-binding
Biological processProtein biosynthesis, Translation regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Probable eukaryotic translation initiation factor 4 gamma homolog
Short name:
eIF-4-gamma
Gene namesi
Name:EIF4G
ORF Names:NCER_100836
OrganismiNosema ceranae (strain BRL01) (Microsporidian parasite)
Taxonomic identifieri578460 [NCBI]
Taxonomic lineageiEukaryotaFungiFungi incertae sedisMicrosporidiaNosematidaeNosema
Proteomesi
  • UP000009082 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiMicrosporidiaDB:NCER_100836

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003884371 – 598Probable eukaryotic translation initiation factor 4 gamma homologAdd BLAST598

Proteomic databases

PRIDEiC4V8K5

Interactioni

Subunit structurei

Component of the eIF4F complex, which composition varies with external and internal environmental conditions.By similarity

Structurei

3D structure databases

SMRiC4V8K5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini209 – 434MIF4GAdd BLAST226

Sequence similaritiesi

Phylogenomic databases

InParanoidiC4V8K5
KOiK03260
OrthoDBiEOG092C28ZF

Family and domain databases

Gene3Di1.25.40.180, 1 hit
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR016021 MIF4-like_sf
IPR003890 MIF4G-like_typ-3
PfamiView protein in Pfam
PF02854 MIF4G, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit

Sequencei

Sequence statusi: Complete.

C4V8K5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVNEVPTLKK KIIFKYFKPL LTFTKKEDPY ELRVKSAPPL NIIEERKEPK
60 70 80 90 100
KFVLCKPDGT PITLDDLSDI SDSEEEEDTK LDMKDSIKED VKDSIKEDVK
110 120 130 140 150
DSSKEDVKDD VIEDVKGSIN EEINSTCGTC SFINLKREKI LNELLEMYRV
160 170 180 190 200
EESVPYSFVP TNVPQIMYSV GEILNCINKI PFTLKLLKKD VNKIPVNYKE
210 220 230 240 250
FKINKETIIE KATFELNKLT NTNIKRIITN LKNLNIETIQ QAKYLGNLIV
260 270 280 290 300
FKAINEPQYC NLYAMVVGAL KKDFKSKEEL GLHKKQTAFF GTVLTSAMKV
310 320 330 340 350
LEEKVEWADT KVLDKNLYKN AFEYERAFEE QETERYLRKK KTLGAVNLLC
360 370 380 390 400
DLYNLDVITL KHIQSRLNEF LNIENEEVVE VLGKFIEKIG EKMYLNDKSD
410 420 430 440 450
YANMICSYLD ACKNKYSNRV KFYIMDVLDK KKNWKKPVSK TENLFSSLIM
460 470 480 490 500
EDEPALDTPY QYQEQVIANE EEEDSLELLK TIDNIYQDLK DAYDEEDEIM
510 520 530 540 550
IADNFKIASN TFGKISFFST YFSECITNSR KSKLLVPFVI NFFNETNLNE
560 570 580 590
SELFDIINKH KEKLNELKID FPLSQKIMSL YVINFVVDRL SKKIHMIN
Length:598
Mass (Da):69,759
Last modified:July 28, 2009 - v1
Checksum:i0098C68E1D101797
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACOL01000057 Genomic DNA Translation: EEQ82443.1
RefSeqiXP_002996114.1, XM_002996068.1

Genome annotation databases

EnsemblFungiiEEQ82443; EEQ82443; NCER_100836
KEGGince:NCER_100836

Similar proteinsi

Entry informationi

Entry nameiIF4G_NOSCE
AccessioniPrimary (citable) accession number: C4V8K5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: July 28, 2009
Last modified: May 23, 2018
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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