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C4V819 (SYQ_NOSCE) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable glutamine--tRNA ligase

EC=6.1.1.18
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name=GlnRS
Gene names
ORF Names:NCER_100619
OrganismNosema ceranae (strain BRL01) (Microsporidian parasite) [Complete proteome]
Taxonomic identifier578460 [NCBI]
Taxonomic lineageEukaryotaFungiMicrosporidiaNosematidaeNosema

Protein attributes

Sequence length695 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutaminyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: InterPro

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glutamine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 695695Probable glutamine--tRNA ligase
PRO_0000388383

Regions

Motif201 – 21111"HIGH" region By similarity
Motif446 – 4505"KMSKS" region By similarity

Sites

Binding site4491ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
C4V819 [UniParc].

Last modified July 28, 2009. Version 1.
Checksum: B37230F4F506F579

FASTA69581,524
        10         20         30         40         50         60 
MFDVESLLKK LNVSEDKKEN ILQKEQLKKN LETLYTNFDT DNKLLFTLAC TAPKKIDILI 

        70         80         90        100        110        120 
FGILINENVI KNDATLRASM KFAIKNTDVT YEELKDFILK NTKSKEEVSE IINKACLSGK 

       130        140        150        160        170        180 
SKKEVYIILK NKLPFEDSKY LMDEVNKFEI DTSKSKKVKD WLEEGEVSML HKPGDNPQLN 

       190        200        210        220        230        240 
EKILKDHLER TGGKVVTRFP PEPNGILHIG HAKAINLDFG YAEKYNGICY LRFDDTNPRN 

       250        260        270        280        290        300 
EEDYYFESII EDVKWLGFEP YAITSSSKYF GDMCELAEKL ILKDKAYICE LSNEELKKRR 

       310        320        330        340        350        360 
RMLSEAFETD KDKSIEELGL ILSPYRNREI SENLKIFREM VEKKHKEGDY TLRFKMDIRS 

       370        380        390        400        410        420 
KNPMMFDLVG MRIIDCDHVV TKDKYNLYPS YEFALCVSDS LEDVTHSFCT REFFTRQESY 

       430        440        450        460        470        480 
KWLLDALEIY KPVQWEFSRL NISNTVLSKR KIVPLKKYGI ELDDPRLYTI KGMRRRGIPP 

       490        500        510        520        530        540 
QAINNFVKSL GITYAETIID NKKFESFIRD ELNKTTQRVM CVMDPLKIYI RNAKEQEISI 

       550        560        570        580        590        600 
PNSNQKIIFK PYIYIEKSDF KMEDDDKDFL RFTPNQSVGL YMFGAIKFIK FDNDMIIAEL 

       610        620        630        640        650        660 
TNETPKKFIH WVSCDSIKVT IRLYDPLFRS FNPEEGNYLD NINLDSLKTV VGYCDDRIKG 

       670        680        690 
CEVEDKFQFQ RVGYFCVDPD TTPENIVFNR IITLI 

« Hide

References

[1]"Genomic analyses of the microsporidian Nosema ceranae, an emergent pathogen of honey bees."
Cornman R.S., Chen Y.P., Schatz M.C., Street C., Zhao Y., Desany B., Egholm M., Hutchison S., Pettis J.S., Lipkin W.I., Evans J.D.
PLoS Pathog. 5:E1000466-E1000466(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BRL01.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
ACOL01000036 Genomic DNA. Translation: EEQ82641.1.
RefSeqXP_002996312.1. XM_002996266.1.

3D structure databases

ProteinModelPortalC4V819.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID9422611.
KEGGnce:NCER_100619.

Organism-specific databases

EuPathDBMicrosporidiaDB:NCER_100619.

Phylogenomic databases

KOK01886.
OrthoDBEOG7MD4ZK.

Family and domain databases

Gene3D1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR10119. PTHR10119. 1 hit.
PfamPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
SUPFAMSSF50715. SSF50715. 1 hit.
TIGRFAMsTIGR00440. glnS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYQ_NOSCE
AccessionPrimary (citable) accession number: C4V819
Entry history
Integrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: July 28, 2009
Last modified: November 13, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries