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Protein

Probable glutamine--tRNA ligase

Gene

NCER_100619

Organism
Nosema ceranae (strain BRL01) (Microsporidian parasite)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei234L-glutamineBy similarity1
Binding sitei391L-glutamineBy similarity1
Binding sitei410ATPBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi202 – 204ATPBy similarity3
Nucleotide bindingi208 – 214ATPBy similarity7
Nucleotide bindingi439 – 440ATPBy similarity2
Nucleotide bindingi447 – 449ATPBy similarity3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glutamine--tRNA ligase (EC:6.1.1.18By similarity)
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name:
GlnRS
Gene namesi
ORF Names:NCER_100619
OrganismiNosema ceranae (strain BRL01) (Microsporidian parasite)
Taxonomic identifieri578460 [NCBI]
Taxonomic lineageiEukaryotaFungiFungi incertae sedisMicrosporidiaNosematidaeNosema
Proteomesi
  • UP000009082 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiMicrosporidiaDB:NCER_100619

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003883831 – 695Probable glutamine--tRNA ligaseAdd BLAST695

Proteomic databases

PRIDEiC4V819

Structurei

3D structure databases

ProteinModelPortaliC4V819
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi201 – 211"HIGH" regionBy similarityAdd BLAST11
Motifi446 – 450"KMSKS" regionBy similarity5

Sequence similaritiesi

Phylogenomic databases

InParanoidiC4V819
KOiK01886
OrthoDBiEOG092C0PFH

Family and domain databases

Gene3Di2.40.240.10, 3 hits
3.40.50.620, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR004514 Gln-tRNA-synth
IPR000924 Glu/Gln-tRNA-synth
IPR020058 Glu/Gln-tRNA-synth_Ib_cat-dom
IPR020059 Glu/Gln-tRNA-synth_Ib_codon-bd
IPR020056 Rbsml_L25/Gln-tRNA_synth_N
IPR011035 Ribosomal_L25/Gln-tRNA_synth
IPR014729 Rossmann-like_a/b/a_fold
PfamiView protein in Pfam
PF00749 tRNA-synt_1c, 1 hit
PF03950 tRNA-synt_1c_C, 1 hit
PRINTSiPR00987 TRNASYNTHGLU
SUPFAMiSSF50715 SSF50715, 1 hit
TIGRFAMsiTIGR00440 glnS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

C4V819-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFDVESLLKK LNVSEDKKEN ILQKEQLKKN LETLYTNFDT DNKLLFTLAC
60 70 80 90 100
TAPKKIDILI FGILINENVI KNDATLRASM KFAIKNTDVT YEELKDFILK
110 120 130 140 150
NTKSKEEVSE IINKACLSGK SKKEVYIILK NKLPFEDSKY LMDEVNKFEI
160 170 180 190 200
DTSKSKKVKD WLEEGEVSML HKPGDNPQLN EKILKDHLER TGGKVVTRFP
210 220 230 240 250
PEPNGILHIG HAKAINLDFG YAEKYNGICY LRFDDTNPRN EEDYYFESII
260 270 280 290 300
EDVKWLGFEP YAITSSSKYF GDMCELAEKL ILKDKAYICE LSNEELKKRR
310 320 330 340 350
RMLSEAFETD KDKSIEELGL ILSPYRNREI SENLKIFREM VEKKHKEGDY
360 370 380 390 400
TLRFKMDIRS KNPMMFDLVG MRIIDCDHVV TKDKYNLYPS YEFALCVSDS
410 420 430 440 450
LEDVTHSFCT REFFTRQESY KWLLDALEIY KPVQWEFSRL NISNTVLSKR
460 470 480 490 500
KIVPLKKYGI ELDDPRLYTI KGMRRRGIPP QAINNFVKSL GITYAETIID
510 520 530 540 550
NKKFESFIRD ELNKTTQRVM CVMDPLKIYI RNAKEQEISI PNSNQKIIFK
560 570 580 590 600
PYIYIEKSDF KMEDDDKDFL RFTPNQSVGL YMFGAIKFIK FDNDMIIAEL
610 620 630 640 650
TNETPKKFIH WVSCDSIKVT IRLYDPLFRS FNPEEGNYLD NINLDSLKTV
660 670 680 690
VGYCDDRIKG CEVEDKFQFQ RVGYFCVDPD TTPENIVFNR IITLI
Length:695
Mass (Da):81,524
Last modified:July 28, 2009 - v1
Checksum:iB37230F4F506F579
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACOL01000036 Genomic DNA Translation: EEQ82641.1
RefSeqiXP_002996312.1, XM_002996266.1

Genome annotation databases

EnsemblFungiiEEQ82641; EEQ82641; NCER_100619
KEGGince:NCER_100619

Similar proteinsi

Entry informationi

Entry nameiSYQ_NOSCE
AccessioniPrimary (citable) accession number: C4V819
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: July 28, 2009
Last modified: May 23, 2018
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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