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C4V7S3

- C4V7S3_NOSCE

UniProt

C4V7S3 - C4V7S3_NOSCE

Protein

DNA ligase

Gene

NCER_100511

Organism
Nosema ceranae (strain BRL01) (Microsporidian parasite)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (28 Jul 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotation

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    ORF Names:NCER_100511Imported
    OrganismiNosema ceranae (strain BRL01) (Microsporidian parasite)Imported
    Taxonomic identifieri578460 [NCBI]
    Taxonomic lineageiEukaryotaFungiMicrosporidiaNosematidaeNosema
    ProteomesiUP000009082: Unassembled WGS sequence

    Organism-specific databases

    EuPathDBiMicrosporidiaDB:NCER_100511.

    Structurei

    3D structure databases

    ProteinModelPortaliC4V7S3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    KOiK10747.
    OrthoDBiEOG7TXKRG.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProiIPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C4V7S3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MENEIKPNSF LYFSKIMEKI SQRSGRIEIQ DMLTEYFRDV ISINKNDLIY    50
    VIYLCTHTIY PEYKNQQLNL GEKILFDVLK ECTSKDITIL KKEYTKIGDF 100
    GTIGMTYRTR QLFISKKTLS AKDVVYALRE IAEISGIKSR IYKIRKMLDL 150
    ISSCTPIEIK FLFRLFEENL KVKFALKTVL AAFAKLYDSA YIDKIKEAYN 200
    RRPDIEQLVI EILTNGISTV DTNFNIEPGI PLKPMLAQPT KNISTAFKRV 250
    ENKKFTCENK YDGERIQIHR HNNQMTLYSR NLENTTDKYF DIIIKSNTDK 300
    DFVIDGEVVA YDPEQKKILT FQKLSTRKRK DFSKKETVNV CVFVFDILYF 350
    DGLELINKSL EDRRAILHKE FTEVEGKFFF SEFKDCENIE EVDEFFRQSI 400
    NSQYEGIMIK LLGDGSNYIP SQRCNSWIKL KKDYIESGSD SFDLVVVGAY 450
    YGKGKRTGWY GGFLLASYNE NDEMFETVCK IGTGFDDSLL SKLYEEVNNY 500
    VVSIPSRVKY KEQTKPDVWI TPKFVWEIKA AAVSASPIYC CGIDIEEKGF 550
    SLRFPRFLNE REDKDVTDAT TSLQIVMNYK EYEGESKVLD DI 592
    Length:592
    Mass (Da):68,957
    Last modified:July 28, 2009 - v1
    Checksum:iF712EDDBEDD29EB3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    ACOL01000027 Genomic DNA. Translation: EEQ82740.1.
    RefSeqiXP_002996411.1. XM_002996365.1.

    Genome annotation databases

    GeneIDi9422802.
    KEGGince:NCER_100511.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    ACOL01000027 Genomic DNA. Translation: EEQ82740.1 .
    RefSeqi XP_002996411.1. XM_002996365.1.

    3D structure databases

    ProteinModelPortali C4V7S3.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 9422802.
    KEGGi nce:NCER_100511.

    Organism-specific databases

    EuPathDBi MicrosporidiaDB:NCER_100511.

    Phylogenomic databases

    KOi K10747.
    OrthoDBi EOG7TXKRG.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProi IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genomic analyses of the microsporidian Nosema ceranae, an emergent pathogen of honey bees."
      Cornman R.S., Chen Y.P., Schatz M.C., Street C., Zhao Y., Desany B., Egholm M., Hutchison S., Pettis J.S., Lipkin W.I., Evans J.D.
      PLoS Pathog. 5:E1000466-E1000466(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BRL01Imported.

    Entry informationi

    Entry nameiC4V7S3_NOSCE
    AccessioniPrimary (citable) accession number: C4V7S3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 28, 2009
    Last sequence update: July 28, 2009
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3