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C4V7S3

- C4V7S3_NOSCE

UniProt

C4V7S3 - C4V7S3_NOSCE

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Protein
DNA ligase
Gene
NCER_100511
Organism
Nosema ceranae (strain BRL01) (Microsporidian parasite)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:NCER_100511Imported
OrganismiNosema ceranae (strain BRL01) (Microsporidian parasite)
Taxonomic identifieri578460 [NCBI]
Taxonomic lineageiEukaryotaFungiMicrosporidiaNosematidaeNosema
ProteomesiUP000009082: Unassembled WGS sequence

Organism-specific databases

EuPathDBiMicrosporidiaDB:NCER_100511.

Structurei

3D structure databases

ProteinModelPortaliC4V7S3.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C4V7S3-1 [UniParc]FASTAAdd to Basket

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MENEIKPNSF LYFSKIMEKI SQRSGRIEIQ DMLTEYFRDV ISINKNDLIY    50
VIYLCTHTIY PEYKNQQLNL GEKILFDVLK ECTSKDITIL KKEYTKIGDF 100
GTIGMTYRTR QLFISKKTLS AKDVVYALRE IAEISGIKSR IYKIRKMLDL 150
ISSCTPIEIK FLFRLFEENL KVKFALKTVL AAFAKLYDSA YIDKIKEAYN 200
RRPDIEQLVI EILTNGISTV DTNFNIEPGI PLKPMLAQPT KNISTAFKRV 250
ENKKFTCENK YDGERIQIHR HNNQMTLYSR NLENTTDKYF DIIIKSNTDK 300
DFVIDGEVVA YDPEQKKILT FQKLSTRKRK DFSKKETVNV CVFVFDILYF 350
DGLELINKSL EDRRAILHKE FTEVEGKFFF SEFKDCENIE EVDEFFRQSI 400
NSQYEGIMIK LLGDGSNYIP SQRCNSWIKL KKDYIESGSD SFDLVVVGAY 450
YGKGKRTGWY GGFLLASYNE NDEMFETVCK IGTGFDDSLL SKLYEEVNNY 500
VVSIPSRVKY KEQTKPDVWI TPKFVWEIKA AAVSASPIYC CGIDIEEKGF 550
SLRFPRFLNE REDKDVTDAT TSLQIVMNYK EYEGESKVLD DI 592
Length:592
Mass (Da):68,957
Last modified:July 28, 2009 - v1
Checksum:iF712EDDBEDD29EB3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
ACOL01000027 Genomic DNA. Translation: EEQ82740.1.
RefSeqiXP_002996411.1. XM_002996365.1.

Genome annotation databases

GeneIDi9422802.
KEGGince:NCER_100511.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
ACOL01000027 Genomic DNA. Translation: EEQ82740.1 .
RefSeqi XP_002996411.1. XM_002996365.1.

3D structure databases

ProteinModelPortali C4V7S3.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 9422802.
KEGGi nce:NCER_100511.

Organism-specific databases

EuPathDBi MicrosporidiaDB:NCER_100511.

Phylogenomic databases

KOi K10747.
OrthoDBi EOG7TXKRG.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProi IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genomic analyses of the microsporidian Nosema ceranae, an emergent pathogen of honey bees."
    Cornman R.S., Chen Y.P., Schatz M.C., Street C., Zhao Y., Desany B., Egholm M., Hutchison S., Pettis J.S., Lipkin W.I., Evans J.D.
    PLoS Pathog. 5:E1000466-E1000466(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BRL01.

Entry informationi

Entry nameiC4V7S3_NOSCE
AccessioniPrimary (citable) accession number: C4V7S3
Entry historyi
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: November 13, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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