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Protein

Superoxide dismutase [Cu-Zn]

Gene

PAS_chr4_0786

Organism
Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • Cu cationUniRule annotationNote: Binds 1 copper ion per subunit.UniRule annotation
  • Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandCopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:PAS_chr4_0786Imported
OrganismiKomagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)Imported
Taxonomic identifieri644223 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesPhaffomycetaceaeKomagataella
Proteomesi
  • UP000000314 Componenti: Chromosome 4

Interactioni

Protein-protein interaction databases

STRINGi644223.XP_002494231.1.

Structurei

3D structure databases

ProteinModelPortaliC4R8X7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 150Sod_CuInterPro annotationAdd BLAST140

Sequence similaritiesi

Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0441. Eukaryota.
COG2032. LUCA.
HOGENOMiHOG000263447.
InParanoidiC4R8X7.
KOiK04565.
OMAiIHTFGDN.
OrthoDBiEOG092C578I.

Family and domain databases

CDDicd00305. Cu-Zn_Superoxide_Dismutase. 1 hit.
Gene3Di2.60.40.200. 1 hit.
InterProiView protein in InterPro
IPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
PfamiView protein in Pfam
PF00080. Sod_Cu. 1 hit.
PRINTSiPR00068. CUZNDISMTASE.
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiView protein in PROSITE
PS00087. SOD_CU_ZN_1. 1 hit.
PS00332. SOD_CU_ZN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

C4R8X7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVKAVAVLRG DSTVGGTVVF EQSSESSPTT ITYDIKGNSP NAERGFHIHQ
60 70 80 90 100
FGDNTNGCTS AGPHFNPFGK THGAPTDEAR HVGDLGNVKT DAEGVAKGVI
110 120 130 140 150
TDNQVKLIGE TSILGRTVVI HDGTDDLGKG GHADSLKTGN AGGRPACGVI

GLAA
Length:154
Mass (Da):15,677
Last modified:July 7, 2009 - v1
Checksum:iCF7664E37B7B0991
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN392322 Genomic DNA. Translation: CAY72052.1.
RefSeqiXP_002494231.1. XM_002494186.1.

Genome annotation databases

EnsemblFungiiCAY72052; CAY72052; PAS_chr4_0786.
GeneIDi8200564.
KEGGippa:PAS_chr4_0786.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiC4R8X7_KOMPG
AccessioniPrimary (citable) accession number: C4R8X7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: June 7, 2017
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported