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Protein

Hexokinase

Gene

PAS_chr4_0624

Organism
Komagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. hexokinase activity Source: InterPro

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:PAS_chr4_0624Imported
OrganismiKomagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)Imported
Taxonomic identifieri644223 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesPhaffomycetaceaeKomagataella
ProteomesiUP000000314: Chromosome 4

Interactioni

Protein-protein interaction databases

STRINGi644223.PAS_chr4_0624.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation
Contains 1 hexokinase type-1 domain.UniRule annotation
Contains 1 hexokinase type-2 domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG5026.
HOGENOMiHOG000162670.
InParanoidiC4R8F9.
KOiK00844.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C4R8F9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLQEAVKEI QSSFDVSQEV LQRSVDKFIE LAKKGLASNE DKLGMPMLPA
60 70 80 90 100
YVTQVPSGKE KGTYLAADLG GTNFRVCSVH LKGDNTFNLV QQKSPIPADM
110 120 130 140 150
MVGTGDQLFA YLASKIRKFL EEHHGDALEA AHETNSRANY LKLGFTFSFP
160 170 180 190 200
TAQHSLDSGS LVRWTKGFNI PDVVDQDVVQ LLQKHLDAGK IPVHVAALAN
210 220 230 240 250
DTVGTLLSRA YSANAIAGGK QGETIIGAIF GTGTNGAYLE KLDNIKKLPE
260 270 280 290 300
AVVKDLKAKG VTHMVINTEW GSFDNRLEVL PTTKYDRDVD ALTANPGIHL
310 320 330 340 350
FEKRVSGMFM GEILRNILVD FHSRGLVFTQ YPNFESLPHR LRTPWDLDSE
360 370 380 390 400
NLSLFEVDDS KDMKPTEVTL LQALRLPTTL EERQAIQALT RAISRRSAYI
410 420 430 440 450
SAVPIAAIIM LTGALEGHHI EVDIGVDGSV VEFYPGYRTM LRDALALTQI
460 470
GTKGERRTHI NIAKDGSGVG AALCASVSI
Length:479
Mass (Da):52,376
Last modified:July 7, 2009 - v1
Checksum:i099F3B704E7275EE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN392322 Genomic DNA. Translation: CAY71884.1.
RefSeqiXP_002494063.1. XM_002494018.1.

Genome annotation databases

EnsemblFungiiCAY71884; CAY71884; PAS_chr4_0624.
GeneIDi8201333.
KEGGippa:PAS_chr4_0624.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN392322 Genomic DNA. Translation: CAY71884.1.
RefSeqiXP_002494063.1. XM_002494018.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi644223.PAS_chr4_0624.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAY71884; CAY71884; PAS_chr4_0624.
GeneIDi8201333.
KEGGippa:PAS_chr4_0624.

Phylogenomic databases

eggNOGiCOG5026.
HOGENOMiHOG000162670.
InParanoidiC4R8F9.
KOiK00844.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GS115 / ATCC 20864Imported.

Entry informationi

Entry nameiC4R8F9_PICPG
AccessioniPrimary (citable) accession number: C4R8F9
Entry historyi
Integrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: March 4, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.