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C4R864

- C4R864_PICPG

UniProt

C4R864 - C4R864_PICPG

Protein

Mitogen-activated protein kinase

Gene

PAS_chr4_0530

Organism
Komagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 38 (01 Oct 2014)
      Sequence version 1 (07 Jul 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.UniRule annotationSAAS annotation

    Cofactori

    Magnesium.UniRule annotation

    Enzyme regulationi

    Activated by threonine and tyrosine phosphorylation.UniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. MAP kinase activity Source: InterPro
    3. transaminase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    AminotransferaseImported, Kinase, Serine/threonine-protein kinaseUniRule annotationSAAS annotation, Transferase

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, MagnesiumUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Mitogen-activated protein kinaseUniRule annotation (EC:2.7.11.24UniRule annotation)
    Gene namesi
    Ordered Locus Names:PAS_chr4_0530Imported
    OrganismiKomagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)Imported
    Taxonomic identifieri644223 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKomagataella
    ProteomesiUP000000314: Chromosome 4

    Interactioni

    Protein-protein interaction databases

    STRINGi644223.PAS_chr4_0530.

    Structurei

    3D structure databases

    ProteinModelPortaliC4R864.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.UniRule annotation
    Contains 1 protein kinase domain.UniRule annotation
    Contains protein kinase domain.SAAS annotation

    Phylogenomic databases

    eggNOGiCOG0515.
    HOGENOMiHOG000233024.
    KOiK04371.
    OrthoDBiEOG7K3TWD.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR003527. MAP_kinase_CS.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SMARTiSM00220. S_TKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS01351. MAPK. 1 hit.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C4R864-1 [UniParc]FASTAAdd to Basket

    « Hide

    MASGQRSISF NVSHHYQILD IVGEGAYGVV CSAIHLPSQQ KVAIKKIVPF    50
    SKPMFCLRTL RELKLLKHFN HENIISILDI QVPYDFSSFH EVYLIQELME 100
    TDLHRVIRTQ QLSDDHCQYF VYQTLRALKA LHSANVLHRD LKPSNLLLNA 150
    NCDLKVCDFG LARSVAKTED NYGFMTEYVA TRWYRAPEIM LTFQEYTAAI 200
    DVWSVGCILA EMLSGTPLFP GKDYHHQLSL IFDVLGTPGK EDLAAIKSPR 250
    PREYVGSMTP RPGVDFKTLF PGANPLGLDL LSRLLTFSPA RRICVDDALR 300
    HPYLQLYHDP NDEPVAAPLE DDFFDFDRRK EELTMLDLKE LLYEEIIKPL 350
    Q 351
    Length:351
    Mass (Da):40,187
    Last modified:July 7, 2009 - v1
    Checksum:i60431731E95C6940
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN392322 Genomic DNA. Translation: CAY71789.1.
    RefSeqiXP_002493968.1. XM_002493923.1.

    Genome annotation databases

    EnsemblFungiiCAY71789; CAY71789; PAS_chr4_0530.
    GeneIDi8201008.
    KEGGippa:PAS_chr4_0530.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN392322 Genomic DNA. Translation: CAY71789.1 .
    RefSeqi XP_002493968.1. XM_002493923.1.

    3D structure databases

    ProteinModelPortali C4R864.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 644223.PAS_chr4_0530.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CAY71789 ; CAY71789 ; PAS_chr4_0530 .
    GeneIDi 8201008.
    KEGGi ppa:PAS_chr4_0530.

    Phylogenomic databases

    eggNOGi COG0515.
    HOGENOMi HOG000233024.
    KOi K04371.
    OrthoDBi EOG7K3TWD.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR003527. MAP_kinase_CS.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SMARTi SM00220. S_TKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS01351. MAPK. 1 hit.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: GS115 / ATCC 20864Imported.

    Entry informationi

    Entry nameiC4R864_PICPG
    AccessioniPrimary (citable) accession number: C4R864
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 7, 2009
    Last sequence update: July 7, 2009
    Last modified: October 1, 2014
    This is version 38 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3