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C4R864

- C4R864_PICPG

UniProt

C4R864 - C4R864_PICPG

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Protein

Mitogen-activated protein kinase

Gene

PAS_chr4_0530

Organism
Komagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.UniRule annotationSAAS annotation

Cofactori

Note: Magnesium.UniRule annotation

Enzyme regulationi

Activated by threonine and tyrosine phosphorylation.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. MAP kinase activity Source: UniProtKB-EC
  3. transaminase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Kinase, Serine/threonine-protein kinaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, MagnesiumUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Mitogen-activated protein kinaseUniRule annotation (EC:2.7.11.24UniRule annotation)
Gene namesi
Ordered Locus Names:PAS_chr4_0530Imported
OrganismiKomagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)Imported
Taxonomic identifieri644223 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesPhaffomycetaceaeKomagataella
ProteomesiUP000000314: Chromosome 4

Interactioni

Protein-protein interaction databases

STRINGi644223.PAS_chr4_0530.

Structurei

3D structure databases

ProteinModelPortaliC4R864.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.UniRule annotation
Contains 1 protein kinase domain.UniRule annotation
Contains protein kinase domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000233024.
InParanoidiC4R864.
KOiK04371.
OrthoDBiEOG7K3TWD.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS01351. MAPK. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C4R864-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MASGQRSISF NVSHHYQILD IVGEGAYGVV CSAIHLPSQQ KVAIKKIVPF
60 70 80 90 100
SKPMFCLRTL RELKLLKHFN HENIISILDI QVPYDFSSFH EVYLIQELME
110 120 130 140 150
TDLHRVIRTQ QLSDDHCQYF VYQTLRALKA LHSANVLHRD LKPSNLLLNA
160 170 180 190 200
NCDLKVCDFG LARSVAKTED NYGFMTEYVA TRWYRAPEIM LTFQEYTAAI
210 220 230 240 250
DVWSVGCILA EMLSGTPLFP GKDYHHQLSL IFDVLGTPGK EDLAAIKSPR
260 270 280 290 300
PREYVGSMTP RPGVDFKTLF PGANPLGLDL LSRLLTFSPA RRICVDDALR
310 320 330 340 350
HPYLQLYHDP NDEPVAAPLE DDFFDFDRRK EELTMLDLKE LLYEEIIKPL

Q
Length:351
Mass (Da):40,187
Last modified:July 7, 2009 - v1
Checksum:i60431731E95C6940
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN392322 Genomic DNA. Translation: CAY71789.1.
RefSeqiXP_002493968.1. XM_002493923.1.

Genome annotation databases

EnsemblFungiiCAY71789; CAY71789; PAS_chr4_0530.
GeneIDi8201008.
KEGGippa:PAS_chr4_0530.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN392322 Genomic DNA. Translation: CAY71789.1 .
RefSeqi XP_002493968.1. XM_002493923.1.

3D structure databases

ProteinModelPortali C4R864.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 644223.PAS_chr4_0530.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CAY71789 ; CAY71789 ; PAS_chr4_0530 .
GeneIDi 8201008.
KEGGi ppa:PAS_chr4_0530.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000233024.
InParanoidi C4R864.
KOi K04371.
OrthoDBi EOG7K3TWD.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS01351. MAPK. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GS115 / ATCC 20864Imported.

Entry informationi

Entry nameiC4R864_PICPG
AccessioniPrimary (citable) accession number: C4R864
Entry historyi
Integrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: November 26, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3