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C4R6J3

- C4R6J3_PICPG

UniProt

C4R6J3 - C4R6J3_PICPG

Protein

DNA ligase

Gene

PAS_chr3_1112

Organism
Komagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 37 (01 Oct 2014)
      Sequence version 1 (07 Jul 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotationImported

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:PAS_chr3_1112Imported
    OrganismiKomagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)Imported
    Taxonomic identifieri644223 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKomagataella
    ProteomesiUP000000314: Chromosome 3

    PTM / Processingi

    Proteomic databases

    ProMEXiC4R6J3.

    Interactioni

    Protein-protein interaction databases

    STRINGi644223.PAS_chr3_1112.

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG1793.
    HOGENOMiHOG000036006.
    KOiK10747.
    OrthoDBiEOG7TXKRG.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProiIPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C4R6J3-1 [UniParc]FASTAAdd to Basket

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    MTHCGPLLFP NLDLSRNLSK RLFLCYISYY NCFIMSGQQS LNRFFSARKP    50
    EIVNSTSKKL ISQKRTTETD YSPLKRTKNS TMLECGDLNS PHLAKVGYPD 100
    LEKDTVDSNI LVEAESLLKL ESKYHSDSPD LPQSQEIFYS SLTNIFEKLE 150
    QEPARLKNLA IASEFFLQIL RSNHKRTLVE VIYLMINRLG PDYELDLELG 200
    LGETLLVKAI AEGTGRTPQR IRSELHKLGD IGLVAQNSRS RQPTMFKSKP 250
    LTIHSVFENL TKIAKSSGNA SQARKIGLIN QMLTTCEGSE AKFLMRSLEG 300
    KLRINFGEKS VLVALSKAFS EYEHELSSKK GHVSPQELVD AEEAIKKAFS 350
    QIPNYEIIVD EALKYGISNL ATHCTLKPGI PLKPMLAKPT KSITEVLDHF 400
    HGQEFTCEYK YDGERAQLHV QEDGTVKIYS RNSEDMSQRY PDLIDVVSQI 450
    KTQCNGVITL ILDCECVAWD GEKGKILPFQ VLSTRKRKDV NAKDIKVQVC 500
    LFAFDILFLN GKSLLELPLK ERRKILHENV KPIEGKFQFA EAMDADNVAE 550
    IQHFLDQSVK DSCEGLMVKM LDGDKSHYEP SKRSVNWLKL KKDYLEGVGD 600
    SLDLAVVGGY IGKGKRTGWY GGFLLACYNE DSGEYETCCK IGTGFSEEML 650
    QTLSGTLKPT VIQQPKPFYV YDASPDVWFE PTLVFEVLTA DLSLSPVYKA 700
    GINFFGKGVS LRFPRFIRVR DDKSPEQATS SDQIVELYQK QAHV 744
    Length:744
    Mass (Da):83,945
    Last modified:July 7, 2009 - v1
    Checksum:iDDA84A811C6FBD3B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN392321 Genomic DNA. Translation: CAY71179.1.
    RefSeqiXP_002493358.1. XM_002493313.1.

    Genome annotation databases

    EnsemblFungiiCAY71179; CAY71179; PAS_chr3_1112.
    GeneIDi8200069.
    KEGGippa:PAS_chr3_1112.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN392321 Genomic DNA. Translation: CAY71179.1 .
    RefSeqi XP_002493358.1. XM_002493313.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 644223.PAS_chr3_1112.

    Proteomic databases

    ProMEXi C4R6J3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CAY71179 ; CAY71179 ; PAS_chr3_1112 .
    GeneIDi 8200069.
    KEGGi ppa:PAS_chr3_1112.

    Phylogenomic databases

    eggNOGi COG1793.
    HOGENOMi HOG000036006.
    KOi K10747.
    OrthoDBi EOG7TXKRG.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProi IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: GS115 / ATCC 20864Imported.

    Entry informationi

    Entry nameiC4R6J3_PICPG
    AccessioniPrimary (citable) accession number: C4R6J3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 7, 2009
    Last sequence update: July 7, 2009
    Last modified: October 1, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3