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C4R6J3

- C4R6J3_PICPG

UniProt

C4R6J3 - C4R6J3_PICPG

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Protein

DNA ligase

Gene

PAS_chr3_1112

Organism
Komagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:PAS_chr3_1112Imported
OrganismiKomagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)Imported
Taxonomic identifieri644223 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesPhaffomycetaceaeKomagataella
ProteomesiUP000000314: Chromosome 3

Interactioni

Protein-protein interaction databases

STRINGi644223.PAS_chr3_1112.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1793.
HOGENOMiHOG000036006.
InParanoidiC4R6J3.
KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C4R6J3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTHCGPLLFP NLDLSRNLSK RLFLCYISYY NCFIMSGQQS LNRFFSARKP
60 70 80 90 100
EIVNSTSKKL ISQKRTTETD YSPLKRTKNS TMLECGDLNS PHLAKVGYPD
110 120 130 140 150
LEKDTVDSNI LVEAESLLKL ESKYHSDSPD LPQSQEIFYS SLTNIFEKLE
160 170 180 190 200
QEPARLKNLA IASEFFLQIL RSNHKRTLVE VIYLMINRLG PDYELDLELG
210 220 230 240 250
LGETLLVKAI AEGTGRTPQR IRSELHKLGD IGLVAQNSRS RQPTMFKSKP
260 270 280 290 300
LTIHSVFENL TKIAKSSGNA SQARKIGLIN QMLTTCEGSE AKFLMRSLEG
310 320 330 340 350
KLRINFGEKS VLVALSKAFS EYEHELSSKK GHVSPQELVD AEEAIKKAFS
360 370 380 390 400
QIPNYEIIVD EALKYGISNL ATHCTLKPGI PLKPMLAKPT KSITEVLDHF
410 420 430 440 450
HGQEFTCEYK YDGERAQLHV QEDGTVKIYS RNSEDMSQRY PDLIDVVSQI
460 470 480 490 500
KTQCNGVITL ILDCECVAWD GEKGKILPFQ VLSTRKRKDV NAKDIKVQVC
510 520 530 540 550
LFAFDILFLN GKSLLELPLK ERRKILHENV KPIEGKFQFA EAMDADNVAE
560 570 580 590 600
IQHFLDQSVK DSCEGLMVKM LDGDKSHYEP SKRSVNWLKL KKDYLEGVGD
610 620 630 640 650
SLDLAVVGGY IGKGKRTGWY GGFLLACYNE DSGEYETCCK IGTGFSEEML
660 670 680 690 700
QTLSGTLKPT VIQQPKPFYV YDASPDVWFE PTLVFEVLTA DLSLSPVYKA
710 720 730 740
GINFFGKGVS LRFPRFIRVR DDKSPEQATS SDQIVELYQK QAHV
Length:744
Mass (Da):83,945
Last modified:July 7, 2009 - v1
Checksum:iDDA84A811C6FBD3B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN392321 Genomic DNA. Translation: CAY71179.1.
RefSeqiXP_002493358.1. XM_002493313.1.

Genome annotation databases

EnsemblFungiiCAY71179; CAY71179; PAS_chr3_1112.
GeneIDi8200069.
KEGGippa:PAS_chr3_1112.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN392321 Genomic DNA. Translation: CAY71179.1 .
RefSeqi XP_002493358.1. XM_002493313.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 644223.PAS_chr3_1112.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CAY71179 ; CAY71179 ; PAS_chr3_1112 .
GeneIDi 8200069.
KEGGi ppa:PAS_chr3_1112.

Phylogenomic databases

eggNOGi COG1793.
HOGENOMi HOG000036006.
InParanoidi C4R6J3.
KOi K10747.
OrthoDBi EOG7TXKRG.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProi IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GS115 / ATCC 20864Imported.

Entry informationi

Entry nameiC4R6J3_PICPG
AccessioniPrimary (citable) accession number: C4R6J3
Entry historyi
Integrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: October 29, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3