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C4R6J3

- C4R6J3_PICPG

UniProt

C4R6J3 - C4R6J3_PICPG

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Protein
DNA ligase
Gene
PAS_chr3_1112
Organism
Komagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:PAS_chr3_1112Imported
OrganismiKomagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)
Taxonomic identifieri644223 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKomagataella
ProteomesiUP000000314: Chromosome 3

PTM / Processingi

Proteomic databases

ProMEXiC4R6J3.

Interactioni

Protein-protein interaction databases

STRINGi644223.PAS_chr3_1112.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1793.
HOGENOMiHOG000036006.
KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C4R6J3-1 [UniParc]FASTAAdd to Basket

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MTHCGPLLFP NLDLSRNLSK RLFLCYISYY NCFIMSGQQS LNRFFSARKP    50
EIVNSTSKKL ISQKRTTETD YSPLKRTKNS TMLECGDLNS PHLAKVGYPD 100
LEKDTVDSNI LVEAESLLKL ESKYHSDSPD LPQSQEIFYS SLTNIFEKLE 150
QEPARLKNLA IASEFFLQIL RSNHKRTLVE VIYLMINRLG PDYELDLELG 200
LGETLLVKAI AEGTGRTPQR IRSELHKLGD IGLVAQNSRS RQPTMFKSKP 250
LTIHSVFENL TKIAKSSGNA SQARKIGLIN QMLTTCEGSE AKFLMRSLEG 300
KLRINFGEKS VLVALSKAFS EYEHELSSKK GHVSPQELVD AEEAIKKAFS 350
QIPNYEIIVD EALKYGISNL ATHCTLKPGI PLKPMLAKPT KSITEVLDHF 400
HGQEFTCEYK YDGERAQLHV QEDGTVKIYS RNSEDMSQRY PDLIDVVSQI 450
KTQCNGVITL ILDCECVAWD GEKGKILPFQ VLSTRKRKDV NAKDIKVQVC 500
LFAFDILFLN GKSLLELPLK ERRKILHENV KPIEGKFQFA EAMDADNVAE 550
IQHFLDQSVK DSCEGLMVKM LDGDKSHYEP SKRSVNWLKL KKDYLEGVGD 600
SLDLAVVGGY IGKGKRTGWY GGFLLACYNE DSGEYETCCK IGTGFSEEML 650
QTLSGTLKPT VIQQPKPFYV YDASPDVWFE PTLVFEVLTA DLSLSPVYKA 700
GINFFGKGVS LRFPRFIRVR DDKSPEQATS SDQIVELYQK QAHV 744
Length:744
Mass (Da):83,945
Last modified:July 7, 2009 - v1
Checksum:iDDA84A811C6FBD3B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN392321 Genomic DNA. Translation: CAY71179.1.
RefSeqiXP_002493358.1. XM_002493313.1.

Genome annotation databases

EnsemblFungiiCAY71179; CAY71179; PAS_chr3_1112.
GeneIDi8200069.
KEGGippa:PAS_chr3_1112.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN392321 Genomic DNA. Translation: CAY71179.1 .
RefSeqi XP_002493358.1. XM_002493313.1.

3D structure databases

ModBasei Search...

Protein-protein interaction databases

STRINGi 644223.PAS_chr3_1112.

Proteomic databases

ProMEXi C4R6J3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CAY71179 ; CAY71179 ; PAS_chr3_1112 .
GeneIDi 8200069.
KEGGi ppa:PAS_chr3_1112.

Phylogenomic databases

eggNOGi COG1793.
HOGENOMi HOG000036006.
KOi K10747.
OrthoDBi EOG7TXKRG.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProi IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GS115 / ATCC 20864.

Entry informationi

Entry nameiC4R6J3_PICPG
AccessioniPrimary (citable) accession number: C4R6J3
Entry historyi
Integrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: January 22, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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