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Protein

Glutamate decarboxylase

Gene

PAS_chr3_0965

Organism
Komagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:PAS_chr3_0965Imported
OrganismiKomagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)Imported
Taxonomic identifieri644223 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesPhaffomycetaceaeKomagataella
ProteomesiUP000000314 Componenti: Chromosome 3

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi644223.XP_002493206.1.

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
InParanoidiC4R641.
KOiK01580.
OrthoDBiEOG7P2Z22.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

C4R641-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLSNNTKRR ESSITPDQQK LIEKYLEKKN VHHQKKLQHV THTSTNVNLS
60 70 80 90 100
SIKWKSLRLE DCGVSIPDSG LPAKIAYESI HDSLNLDGNP TLNLASFVNT
110 120 130 140 150
GYINDYSEPL IHENLVKNLA DNDEYPVMLE LHERCLQMLT ELWNGDSKKS
160 170 180 190 200
IGSATTGSSE AIMLGGLAMK KNWQTKRRAA GKSTEKPNII MASCCQVALE
210 220 230 240 250
KFARYFEVDA RIISCDNNDY ILDYDLIYDA CDENTIGIFV ILGSTYTGAF
260 270 280 290 300
EDVALVNKIL DRVEKEKGFD IPIHVDGASG AFVAPFIYPD LEWDFRVPRV
310 320 330 340 350
KSINTSGHKF GLVTAGLGWI VFKDKEWLPK DLVFELRYLG GLEYSFTLNF
360 370 380 390 400
SRPGHQVIHQ YFNFVALGKN GYSSIFDTCL TNARLLSSFL EETNYFKVVS
410 420 430 440 450
NVHRPVEAGT TPHADDHLAF HPSLPVVSFQ FNEEFSKQYP EIPQSIISTL
460 470 480 490 500
MRNKGWIIPN YPLPRTTKPV KDDEREILRV VVRYNLTLEL LQKLMSDIVS
510 520 530 540 550
TLTVLTNSCK LIRESLNNDA LEDTDIIYDM LLSIALDGSE NLVKSSIKDH

KHAGAC
Length:556
Mass (Da):62,772
Last modified:July 7, 2009 - v1
Checksum:i30E32E981AE66A1D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN392321 Genomic DNA. Translation: CAY71027.1.
RefSeqiXP_002493206.1. XM_002493161.1.

Genome annotation databases

EnsemblFungiiCAY71027; CAY71027; PAS_chr3_0965.
GeneIDi8199681.
KEGGippa:PAS_chr3_0965.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN392321 Genomic DNA. Translation: CAY71027.1.
RefSeqiXP_002493206.1. XM_002493161.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi644223.XP_002493206.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAY71027; CAY71027; PAS_chr3_0965.
GeneIDi8199681.
KEGGippa:PAS_chr3_0965.

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
InParanoidiC4R641.
KOiK01580.
OrthoDBiEOG7P2Z22.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GS115 / ATCC 20864Imported.

Entry informationi

Entry nameiC4R641_PICPG
AccessioniPrimary (citable) accession number: C4R641
Entry historyi
Integrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: June 24, 2015
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.