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C4R641

- C4R641_PICPG

UniProt

C4R641 - C4R641_PICPG

Protein

Glutamate decarboxylase

Gene

PAS_chr3_0965

Organism
Komagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (07 Jul 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. glutamate decarboxylase activity Source: InterPro
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. glutamate metabolic process Source: InterPro

    Keywords - Molecular functioni

    DecarboxylaseUniRule annotation, Lyase

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
    Gene namesi
    Ordered Locus Names:PAS_chr3_0965Imported
    OrganismiKomagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)Imported
    Taxonomic identifieri644223 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKomagataella
    ProteomesiUP000000314: Chromosome 3

    Interactioni

    Protein-protein interaction databases

    STRINGi644223.PAS_chr3_0965.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0076.
    HOGENOMiHOG000070228.
    KOiK01580.
    OrthoDBiEOG7P2Z22.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    InterProiIPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view]
    PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    C4R641-1 [UniParc]FASTAAdd to Basket

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    MTLSNNTKRR ESSITPDQQK LIEKYLEKKN VHHQKKLQHV THTSTNVNLS    50
    SIKWKSLRLE DCGVSIPDSG LPAKIAYESI HDSLNLDGNP TLNLASFVNT 100
    GYINDYSEPL IHENLVKNLA DNDEYPVMLE LHERCLQMLT ELWNGDSKKS 150
    IGSATTGSSE AIMLGGLAMK KNWQTKRRAA GKSTEKPNII MASCCQVALE 200
    KFARYFEVDA RIISCDNNDY ILDYDLIYDA CDENTIGIFV ILGSTYTGAF 250
    EDVALVNKIL DRVEKEKGFD IPIHVDGASG AFVAPFIYPD LEWDFRVPRV 300
    KSINTSGHKF GLVTAGLGWI VFKDKEWLPK DLVFELRYLG GLEYSFTLNF 350
    SRPGHQVIHQ YFNFVALGKN GYSSIFDTCL TNARLLSSFL EETNYFKVVS 400
    NVHRPVEAGT TPHADDHLAF HPSLPVVSFQ FNEEFSKQYP EIPQSIISTL 450
    MRNKGWIIPN YPLPRTTKPV KDDEREILRV VVRYNLTLEL LQKLMSDIVS 500
    TLTVLTNSCK LIRESLNNDA LEDTDIIYDM LLSIALDGSE NLVKSSIKDH 550
    KHAGAC 556
    Length:556
    Mass (Da):62,772
    Last modified:July 7, 2009 - v1
    Checksum:i30E32E981AE66A1D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN392321 Genomic DNA. Translation: CAY71027.1.
    RefSeqiXP_002493206.1. XM_002493161.1.

    Genome annotation databases

    EnsemblFungiiCAY71027; CAY71027; PAS_chr3_0965.
    GeneIDi8199681.
    KEGGippa:PAS_chr3_0965.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN392321 Genomic DNA. Translation: CAY71027.1 .
    RefSeqi XP_002493206.1. XM_002493161.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 644223.PAS_chr3_0965.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CAY71027 ; CAY71027 ; PAS_chr3_0965 .
    GeneIDi 8199681.
    KEGGi ppa:PAS_chr3_0965.

    Phylogenomic databases

    eggNOGi COG0076.
    HOGENOMi HOG000070228.
    KOi K01580.
    OrthoDBi EOG7P2Z22.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    InterProi IPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view ]
    PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: GS115 / ATCC 20864Imported.

    Entry informationi

    Entry nameiC4R641_PICPG
    AccessioniPrimary (citable) accession number: C4R641
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 7, 2009
    Last sequence update: July 7, 2009
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3