C4R641 (C4R641_PICPG) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glutamate decarboxylase, converts glutamate into gamma-aminobutyric acid (GABA) EMBL CAY71027.1

Gene names

Ordered Locus Names:

PAS_chr3_0965

Organism

Komagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris) [Complete proteome]

Taxonomic identifier

644223 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Komagataella › Komagataella pastoris

Protein attributes

Sequence length	556 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000382
Sequence similarities	Belongs to the group II decarboxylase family. RuleBase RU000382

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000382
Molecular function	Lyase RuleBase RU000382
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glutamate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	glutamate decarboxylase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C4R641 [UniParc]. Last modified July 7, 2009. Version 1. Checksum: 30E32E981AE66A1D	FASTA	556	62,772
	10 20 30 40 50 60 MTLSNNTKRR ESSITPDQQK LIEKYLEKKN VHHQKKLQHV THTSTNVNLS SIKWKSLRLE 70 80 90 100 110 120 DCGVSIPDSG LPAKIAYESI HDSLNLDGNP TLNLASFVNT GYINDYSEPL IHENLVKNLA 130 140 150 160 170 180 DNDEYPVMLE LHERCLQMLT ELWNGDSKKS IGSATTGSSE AIMLGGLAMK KNWQTKRRAA 190 200 210 220 230 240 GKSTEKPNII MASCCQVALE KFARYFEVDA RIISCDNNDY ILDYDLIYDA CDENTIGIFV 250 260 270 280 290 300 ILGSTYTGAF EDVALVNKIL DRVEKEKGFD IPIHVDGASG AFVAPFIYPD LEWDFRVPRV 310 320 330 340 350 360 KSINTSGHKF GLVTAGLGWI VFKDKEWLPK DLVFELRYLG GLEYSFTLNF SRPGHQVIHQ 370 380 390 400 410 420 YFNFVALGKN GYSSIFDTCL TNARLLSSFL EETNYFKVVS NVHRPVEAGT TPHADDHLAF 430 440 450 460 470 480 HPSLPVVSFQ FNEEFSKQYP EIPQSIISTL MRNKGWIIPN YPLPRTTKPV KDDEREILRV 490 500 510 520 530 540 VVRYNLTLEL LQKLMSDIVS TLTVLTNSCK LIRESLNNDA LEDTDIIYDM LLSIALDGSE 550 NLVKSSIKDH KHAGAC

References

[1]

"Genome sequence of the recombinant protein production host Pichia pastoris." De Schutter K., Lin Y.-C., Tiels P., Van Hecke A., Glinka S., Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N. Nat. Biotechnol. 27:561-566(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GS115 / ATCC 20864.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FN392321 Genomic DNA. Translation: CAY71027.1.
RefSeq	XP_002493206.1. XM_002493161.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	644223.PAS_chr3_0965.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	CAY71027; CAY71027; PAS_chr3_0965.
GeneID	8199681.
KEGG	ppa:PAS_chr3_0965.
Phylogenomic databases
eggNOG	COG0076.
HOGENOM	HOG000070228.
KO	K01580.
OrthoDB	EOG43R6W5.
Family and domain databases
Gene3D	3.40.640.10. 1 hit.
InterPro	IPR010107. Glutamate_decarboxylase. IPR002129. PyrdxlP-dep_de-COase. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. [Graphical view]
PANTHER	PTHR11999:SF1. PTHR11999:SF1. 1 hit.
Pfam	PF00282. Pyridoxal_deC. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C4R641_PICPG

Accession

Primary (citable) accession number: C4R641

Entry history

Integrated into UniProtKB/TrEMBL:	July 7, 2009
Last sequence update:	July 7, 2009
Last modified:	May 1, 2013
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)