UniProtKB - C4R3L1 (C4R3L1_KOMPG)
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Protein
Submitted name:
Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins, cleaves at the C ter
Gene
PAS_chr3_0117
Organism
Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)
Status
Functioni
GO - Molecular functioni
- thiol-dependent ubiquitin-specific protease activity Source: EnsemblFungi
GO - Biological processi
- protein deubiquitination Source: EnsemblFungi
- ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway Source: EnsemblFungi
- ubiquitin recycling Source: EnsemblFungi
Keywordsi
Molecular function | Hydrolase, ProteaseImported |
Names & Taxonomyi
Protein namesi | Submitted name: Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins, cleaves at the C terImported |
Gene namesi | Ordered Locus Names:PAS_chr3_0117Imported |
Organismi | Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)Imported |
Taxonomic identifieri | 644223 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Phaffomycetaceae › Komagataella › |
Proteomesi |
|
Subcellular locationi
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 693 – 1250 | USPInterPro annotationAdd BLAST | 558 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 1139 – 1180 | Sequence analysisAdd BLAST | 42 |
Sequence similaritiesi
Belongs to the peptidase C19 family.SAAS annotation
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
eggNOGi | KOG1863 Eukaryota COG5077 LUCA |
HOGENOMi | HOG000094458 |
InParanoidi | C4R3L1 |
KOi | K11849 |
OMAi | FRKYNDE |
OrthoDBi | EOG092C04TL |
Family and domain databases
InterProi | View protein in InterPro IPR001394 Peptidase_C19_UCH IPR025305 UCH_repeat_domain IPR018200 USP_CS IPR028889 USP_dom |
Pfami | View protein in Pfam PF13446 RPT, 3 hits PF00443 UCH, 1 hit |
PROSITEi | View protein in PROSITE PS00972 USP_1, 1 hit PS50235 USP_3, 1 hit |
i Sequence
Sequence statusi: Complete.
C4R3L1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPDQVPSAST NVNNPFAQLE AYDFSKSKIF KTSNRLIDDI KNSVLFLEQF
60 70 80 90 100
SILNLPAVDY ATQLSLQYQN RQINESFKLV LLNNQLDFAP TVSTEQLPNG
110 120 130 140 150
TRTVFRGLIV QDTVHGIPIS DIPIYHCRIL FKSLENEILC SKHQFFHFSD
160 170 180 190 200
DSLSPSDRSD LVTDYAKISK GELTDCEDDL KPSIVQSCPK LLDSTNYICR
210 220 230 240 250
KCYKVLRIEI FEKDLSNEEY KQFELNEIQF RYSKTVSADP SLNISNENDV
260 270 280 290 300
NKIPSQSECL WTLFKVLRGP LSRDPEELEV KTLDVNHKIL NIHLDMDIFE
310 320 330 340 350
KCLFFHKSAD GSYLTPPLFS EYGVFENLVR ESYIRKLLEV VYLGTICPNN
360 370 380 390 400
PGLKRLNQFA QAYWFNDTGS KIFHFLKEFD STAAIEWFGG LRYDVLERYN
410 420 430 440 450
PALTTLVSAN YFNNKLICGS YSLLCESDPQ NTPKYFDALR DIGLLRQAPV
460 470 480 490 500
VQEFVAKEAS KNVFSFRDTM RNYQILGIDT SSADFPTLSD DEILKFYKYE
510 520 530 540 550
LILANSESSY DRLRNALSSI ADYRKSEALQ NYLRIEPIHN IDQAYKHFDT
560 570 580 590 600
PQSIEDDVLI TAFQFKKDDF PQAVALYDRA LLTIAIQRKS LFLWSYITHN
610 620 630 640 650
LDYLFKVIVA SSSKTITGVE DAYKYLGCDP LATDFQVVTI FQERLIKDPG
660 670 680 690 700
IDVILFFYSL VVIEKSRSSK LIGKFLQNGV VDASFLPLES SPVGLNNIGN
710 720 730 740 750
TCYLNSLLQY YFVIKPLRTA IQNFKDILPS SEEEFNSIED YSKRRIGGRT
760 770 780 790 800
VGYKETERSF QFVYQLRDLF DELIHSRRIA ITPTKELAYL AFSPSTDEVQ
810 820 830 840 850
FHLPEVQKPR PSITESETGM SDAPVPELSP VAMDWSSSIA YPEPSSSHHE
860 870 880 890 900
ESAALNSPDE SSELIHSPTK RKLSPQPSTE DLNEIDTKVS VTNAEPPTTT
910 920 930 940 950
LPKRATTAVA LIGNDQLENA LELGRQQDVT ECIENVLFQL ESASKPTSLD
960 970 980 990 1000
SDDQEQNDLV KELFYGRTKQ ILQPVDKETK ENITDSSVRT KVERFVSLLV
1010 1020 1030 1040 1050
NIGDHPKDLY DALDTYFTED LIDLDDGQVK RSLTITELPK FLQIQVQRVQ
1060 1070 1080 1090 1100
FDRERGIPFK ALDPLPFHEK LYMDRYLETD NEELILKRKE IFQWKNEISK
1110 1120 1130 1140 1150
LNRRKDEILV PSSHSMTPRN ALIATKEFLE AQKELPGDIQ ATESTLITLQ
1160 1170 1180 1190 1200
KEIDILNSEL QTINSRLSEL EEKCQHQFDQ FKNTGYSIFA IFIHRGEASY
1210 1220 1230 1240 1250
GHYWVYIRDP TRNIYRKYND ETITEVPISE VFNFSESNTA TPYFLVFVRE
1260 1270 1280
DLEDEVEPLK RELDSSPTTE DFRISVEELD
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | FN392321 Genomic DNA Translation: CAY70048.1 |
RefSeqi | XP_002492326.1, XM_002492281.1 |
Genome annotation databases
EnsemblFungii | CAY70048; CAY70048; PAS_chr3_0117 |
GeneIDi | 8199397 |
KEGGi | ppa:PAS_chr3_0117 |
Similar proteinsi
Entry informationi
Entry namei | C4R3L1_KOMPG | |
Accessioni | C4R3L1Primary (citable) accession number: C4R3L1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 7, 2009 |
Last sequence update: | July 7, 2009 | |
Last modified: | March 28, 2018 | |
This is version 58 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |