PAS_chr3_0117

Functionⁱ

GO - Molecular functionⁱ

thiol-dependent ubiquitin-specific protease activity Source: EnsemblFungi

Complete GO annotation...

GO - Biological processⁱ

protein deubiquitination Source: EnsemblFungi
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway Source: EnsemblFungi
ubiquitin homeostasis Source: EnsemblFungi

Complete GO annotation...

Keywordsⁱ

Molecular function	Hydrolase, ProteaseImported

Molecular function

Hydrolase, ProteaseImported

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins, cleaves at the C terImported
Gene namesⁱ	Ordered Locus Names:PAS_chr3_0117Imported
Organismⁱ	Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)Imported
Taxonomic identifierⁱ	644223 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Phaffomycetaceae › Komagataella › Komagataella phaffii
Proteomesⁱ	UP000000314 Componentⁱ: Chromosome 3

Subcellular locationⁱ

GO - Cellular componentⁱ

cell Source: GOC

Complete GO annotation...

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	644223.XP_002492326.1.

STRINGⁱ

644223.XP_002492326.1.

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	693 – 1250	USPInterPro annotationAdd BLAST		558

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	1139 – 1180	Sequence analysisAdd BLAST		42

Sequence similaritiesⁱ

Belongs to the peptidase C19 family.SAAS annotation

Keywords - Domainⁱ

Coiled coilSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG1863. Eukaryota. COG5077. LUCA.
HOGENOMⁱ	HOG000094458.
InParanoidⁱ	C4R3L1.
KEGG Orthology (KO) More...KOⁱ	K11849.
OMAⁱ	AVFIHRG.
Database of Orthologous Groups More...OrthoDBⁱ	EOG092C04TL.

Family and domain databases

InterProⁱ	View protein in InterPro IPR001394. Peptidase_C19_UCH. IPR025305. UCH_repeat_domain. IPR018200. USP_CS. IPR028889. USP_dom.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF13446. RPT. 3 hits. PF00443. UCH. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00972. USP_1. 1 hit. PS50235. USP_3. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

C4R3L1-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MPDQVPSAST NVNNPFAQLE AYDFSKSKIF KTSNRLIDDI KNSVLFLEQF 
        60         70         80         90        100
SILNLPAVDY ATQLSLQYQN RQINESFKLV LLNNQLDFAP TVSTEQLPNG 
       110        120        130        140        150
TRTVFRGLIV QDTVHGIPIS DIPIYHCRIL FKSLENEILC SKHQFFHFSD 
       160        170        180        190        200
DSLSPSDRSD LVTDYAKISK GELTDCEDDL KPSIVQSCPK LLDSTNYICR 
       210        220        230        240        250
KCYKVLRIEI FEKDLSNEEY KQFELNEIQF RYSKTVSADP SLNISNENDV 
       260        270        280        290        300
NKIPSQSECL WTLFKVLRGP LSRDPEELEV KTLDVNHKIL NIHLDMDIFE 
       310        320        330        340        350
KCLFFHKSAD GSYLTPPLFS EYGVFENLVR ESYIRKLLEV VYLGTICPNN 
       360        370        380        390        400
PGLKRLNQFA QAYWFNDTGS KIFHFLKEFD STAAIEWFGG LRYDVLERYN 
       410        420        430        440        450
PALTTLVSAN YFNNKLICGS YSLLCESDPQ NTPKYFDALR DIGLLRQAPV 
       460        470        480        490        500
VQEFVAKEAS KNVFSFRDTM RNYQILGIDT SSADFPTLSD DEILKFYKYE 
       510        520        530        540        550
LILANSESSY DRLRNALSSI ADYRKSEALQ NYLRIEPIHN IDQAYKHFDT 
       560        570        580        590        600
PQSIEDDVLI TAFQFKKDDF PQAVALYDRA LLTIAIQRKS LFLWSYITHN 
       610        620        630        640        650
LDYLFKVIVA SSSKTITGVE DAYKYLGCDP LATDFQVVTI FQERLIKDPG 
       660        670        680        690        700
IDVILFFYSL VVIEKSRSSK LIGKFLQNGV VDASFLPLES SPVGLNNIGN 
       710        720        730        740        750
TCYLNSLLQY YFVIKPLRTA IQNFKDILPS SEEEFNSIED YSKRRIGGRT 
       760        770        780        790        800
VGYKETERSF QFVYQLRDLF DELIHSRRIA ITPTKELAYL AFSPSTDEVQ 
       810        820        830        840        850
FHLPEVQKPR PSITESETGM SDAPVPELSP VAMDWSSSIA YPEPSSSHHE 
       860        870        880        890        900
ESAALNSPDE SSELIHSPTK RKLSPQPSTE DLNEIDTKVS VTNAEPPTTT 
       910        920        930        940        950
LPKRATTAVA LIGNDQLENA LELGRQQDVT ECIENVLFQL ESASKPTSLD 
       960        970        980        990       1000
SDDQEQNDLV KELFYGRTKQ ILQPVDKETK ENITDSSVRT KVERFVSLLV 
      1010       1020       1030       1040       1050
NIGDHPKDLY DALDTYFTED LIDLDDGQVK RSLTITELPK FLQIQVQRVQ 
      1060       1070       1080       1090       1100
FDRERGIPFK ALDPLPFHEK LYMDRYLETD NEELILKRKE IFQWKNEISK 
      1110       1120       1130       1140       1150
LNRRKDEILV PSSHSMTPRN ALIATKEFLE AQKELPGDIQ ATESTLITLQ 
      1160       1170       1180       1190       1200
KEIDILNSEL QTINSRLSEL EEKCQHQFDQ FKNTGYSIFA IFIHRGEASY 
      1210       1220       1230       1240       1250
GHYWVYIRDP TRNIYRKYND ETITEVPISE VFNFSESNTA TPYFLVFVRE 
      1260       1270       1280
DLEDEVEPLK RELDSSPTTE DFRISVEELD

Length:1,280

Mass (Da):147,077

Last modified:July 7, 2009 - v1

Checksum:ⁱBB82033A3BE4A38E

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	FN392321 Genomic DNA. Translation: CAY70048.1.
NCBI Reference Sequences More...RefSeqⁱ	XP_002492326.1. XM_002492281.1.

Genome annotation databases

EnsemblFungiⁱ	CAY70048; CAY70048; PAS_chr3_0117.
GeneIDⁱ	8199397.
KEGGⁱ	ppa:PAS_chr3_0117.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	FN392321 Genomic DNA. Translation: CAY70048.1.
NCBI Reference Sequences More...RefSeqⁱ	XP_002492326.1. XM_002492281.1.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	644223.XP_002492326.1.

STRINGⁱ

644223.XP_002492326.1.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblFungiⁱ	CAY70048; CAY70048; PAS_chr3_0117.
GeneIDⁱ	8199397.
KEGGⁱ	ppa:PAS_chr3_0117.

Phylogenomic databases

eggNOGⁱ	KOG1863. Eukaryota. COG5077. LUCA.
HOGENOMⁱ	HOG000094458.
InParanoidⁱ	C4R3L1.
KEGG Orthology (KO) More...KOⁱ	K11849.
OMAⁱ	AVFIHRG.
Database of Orthologous Groups More...OrthoDBⁱ	EOG092C04TL.

Family and domain databases

InterProⁱ	View protein in InterPro IPR001394. Peptidase_C19_UCH. IPR025305. UCH_repeat_domain. IPR018200. USP_CS. IPR028889. USP_dom.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF13446. RPT. 3 hits. PF00443. UCH. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00972. USP_1. 1 hit. PS50235. USP_3. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	C4R3L1_KOMPG
Accessionⁱ	C4R3L1Primary (citable) accession number: C4R3L1
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	July 7, 2009
	Last sequence update:	July 7, 2009
	Last modified:	June 7, 2017
	This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB - C4R3L1 (C4R3L1_KOMPG)

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Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins, cleaves at the C ter

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Interactionⁱ

Protein-protein interaction databases

Family & Domainsⁱ

Domains and Repeats

Coiled coil

Sequence similaritiesⁱ

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - C4R3L1 (C4R3L1_KOMPG)

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Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins, cleaves at the C ter

PAS_chr3_0117

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Interactionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ