Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins, cleaves at the C ter

<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• thiol-dependent ubiquitin-specific protease activity Source: EnsemblFungi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Biological processⁱ

• protein deubiquitination Source: EnsemblFungi
• ubiquitin-dependent protein catabolic process Source: InterPro

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Molecular functionⁱ

<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

<p>Provides information on the location and the topology of the mature protein in the cell.</p><p><a href='../manual/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Cellular componentⁱ

• cytosol Source: EnsemblFungi

<p>Provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.</p><p><a href='../manual/interaction_section' target='_top'>More...</a></p>Interactionⁱ

Protein-protein interaction databases

<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
<p>Describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.</p><p><a href='../manual/domain' target='_top'>More...</a></p>Domaini	693 – 1250	558	USPInterPro annotation <p>Information which has been generated by the UniProtKB automatic annotation system, without manual validation.</p> <p><a href="/manual/evidences#ECO:0000259">More…</a></p> Automatic assertion inferred from signature matchi PROSITE:PS50235			Add BLAST

Coiled coil

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
<p>Denotes the positions of regions of coiled coil within the protein.</p><p><a href='../manual/coiled' target='_top'>More...</a></p>Coiled coili	1139 – 1180	42	Sequence analysis <p>Information which has been generated by the UniProtKB automatic annotation system, without manual validation.</p> <p><a href="/manual/evidences#ECO:0000256">More…</a></p> Automatic assertion according to rulesi SAM:Coils			Add BLAST

<p>Provides information about the sequence similarity with other proteins.</p><p><a href='../manual/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesⁱ

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>Indicates if the <a href="/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.</p><p><a href='../manual/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MPDQVPSAST NVNNPFAQLE AYDFSKSKIF KTSNRLIDDI KNSVLFLEQF 
        60         70         80         90        100
SILNLPAVDY ATQLSLQYQN RQINESFKLV LLNNQLDFAP TVSTEQLPNG 
       110        120        130        140        150
TRTVFRGLIV QDTVHGIPIS DIPIYHCRIL FKSLENEILC SKHQFFHFSD 
       160        170        180        190        200
DSLSPSDRSD LVTDYAKISK GELTDCEDDL KPSIVQSCPK LLDSTNYICR 
       210        220        230        240        250
KCYKVLRIEI FEKDLSNEEY KQFELNEIQF RYSKTVSADP SLNISNENDV 
       260        270        280        290        300
NKIPSQSECL WTLFKVLRGP LSRDPEELEV KTLDVNHKIL NIHLDMDIFE 
       310        320        330        340        350
KCLFFHKSAD GSYLTPPLFS EYGVFENLVR ESYIRKLLEV VYLGTICPNN 
       360        370        380        390        400
PGLKRLNQFA QAYWFNDTGS KIFHFLKEFD STAAIEWFGG LRYDVLERYN 
       410        420        430        440        450
PALTTLVSAN YFNNKLICGS YSLLCESDPQ NTPKYFDALR DIGLLRQAPV 
       460        470        480        490        500
VQEFVAKEAS KNVFSFRDTM RNYQILGIDT SSADFPTLSD DEILKFYKYE 
       510        520        530        540        550
LILANSESSY DRLRNALSSI ADYRKSEALQ NYLRIEPIHN IDQAYKHFDT 
       560        570        580        590        600
PQSIEDDVLI TAFQFKKDDF PQAVALYDRA LLTIAIQRKS LFLWSYITHN 
       610        620        630        640        650
LDYLFKVIVA SSSKTITGVE DAYKYLGCDP LATDFQVVTI FQERLIKDPG 
       660        670        680        690        700
IDVILFFYSL VVIEKSRSSK LIGKFLQNGV VDASFLPLES SPVGLNNIGN 
       710        720        730        740        750
TCYLNSLLQY YFVIKPLRTA IQNFKDILPS SEEEFNSIED YSKRRIGGRT 
       760        770        780        790        800
VGYKETERSF QFVYQLRDLF DELIHSRRIA ITPTKELAYL AFSPSTDEVQ 
       810        820        830        840        850
FHLPEVQKPR PSITESETGM SDAPVPELSP VAMDWSSSIA YPEPSSSHHE 
       860        870        880        890        900
ESAALNSPDE SSELIHSPTK RKLSPQPSTE DLNEIDTKVS VTNAEPPTTT 
       910        920        930        940        950
LPKRATTAVA LIGNDQLENA LELGRQQDVT ECIENVLFQL ESASKPTSLD 
       960        970        980        990       1000
SDDQEQNDLV KELFYGRTKQ ILQPVDKETK ENITDSSVRT KVERFVSLLV 
      1010       1020       1030       1040       1050
NIGDHPKDLY DALDTYFTED LIDLDDGQVK RSLTITELPK FLQIQVQRVQ 
      1060       1070       1080       1090       1100
FDRERGIPFK ALDPLPFHEK LYMDRYLETD NEELILKRKE IFQWKNEISK 
      1110       1120       1130       1140       1150
LNRRKDEILV PSSHSMTPRN ALIATKEFLE AQKELPGDIQ ATESTLITLQ 
      1160       1170       1180       1190       1200
KEIDILNSEL QTINSRLSEL EEKCQHQFDQ FKNTGYSIFA IFIHRGEASY 
      1210       1220       1230       1240       1250
GHYWVYIRDP TRNIYRKYND ETITEVPISE VFNFSESNTA TPYFLVFVRE 
      1260       1270       1280
DLEDEVEPLK RELDSSPTTE DFRISVEELD                       

Sequence databases

Genome annotation databases

<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>Contains any relevant information that doesn’t fit in any other defined sections</p><p><a href='../manual/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ

<p>Provides links to the UniProt Reference Clusters (<a href="/help/uniref">UniRef</a>). UniRef consists of clusters for UniProtKB sequences (including isoforms) and selected UniParc sequences, in order to obtain complete coverage of the sequence space at resolutions of 100%, 90% and 50% identity.</p><p><a href='../manual/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ