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C4R367

- C4R367_PICPG

UniProt

C4R367 - C4R367_PICPG

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Protein
Submitted name:

Nucleosomal histone H3-Lys79 methylase, associates with transcriptionally active genes

Gene

PAS_chr3_1133

Organism
Komagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei504 – 5041S-adenosyl-L-methionineUniRule annotation

GO - Molecular functioni

  1. histone-lysine N-methyltransferase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseImported, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Nucleosomal histone H3-Lys79 methylase, associates with transcriptionally active genesImported
Gene namesi
Ordered Locus Names:PAS_chr3_1133Imported
OrganismiKomagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)Imported
Taxonomic identifieri644223 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesPhaffomycetaceaeKomagataella
ProteomesiUP000000314: Chromosome 3

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi644223.PAS_chr3_1133.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni455 – 4584S-adenosyl-L-methionine bindingUniRule annotation
Regioni478 – 48710S-adenosyl-L-methionine bindingUniRule annotation

Phylogenomic databases

eggNOGiNOG294902.
InParanoidiC4R367.
KOiK11427.
OrthoDBiEOG7KH9VN.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
InterProiIPR013110. DOT1.
IPR025789. Histone_H3-K79_MeTrfase.
IPR021162. Histone_H3-K79_MeTrfase_fungi.
IPR029063. SAM-dependent_MTases-like.
[Graphical view]
PfamiPF08123. DOT1. 1 hit.
[Graphical view]
PIRSFiPIRSF017570. Histone_H3-K79_MeTrfase. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
PROSITEiPS51569. DOT1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C4R367-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGGTKIEDEN NACCLSKELD INPLWQTDET SRDELVQEAL LLESKSGSKP
60 70 80 90 100
AHIAQLLDDS EWYRPSSFNE STVSPRPYNK SNHSAISTCK EGKSIETQGC
110 120 130 140 150
QTNFKTAPSS TSCISKTKGA TKATKILTDK RSASPKALGM TREMKDLWAG
160 170 180 190 200
AAWHLRDNPE YFSSKHQRKR LTQPNNRCNF HDSQTSQETH TGSKKAKKES
210 220 230 240 250
ERPRKEQIKA KSKEVCLKIK NNELPQVETQ FESPDKQPTL EEPSKRFQNK
260 270 280 290 300
IWFIEYDPHN ESQSVLVGNR KFFVDEIYEK QESPVTISNA KSAFALVNET
310 320 330 340 350
KNRYWNDENL PPTAVYLSMP VSSYREKYQL IFPKDEELNP FEEIGRMMEI
360 370 380 390 400
SALFYLPLKY ASLVRNEDSF ANCIVGQFIK AYERSHYEVI LKKIEEYNIL
410 420 430 440 450
IDSLRSSGVI YDHIRAQTKV PRPMIYEILN QVYARTVSPN SKKLRQYKAF
460 470 480 490 500
SNYVYGELLP NFLTQAFNEV KLDSSSKFID LGSGVGNCVF QAALEYGCES
510 520 530 540 550
FGCEIMEHAS FLSELQLIEF KTRCDIFGIK PGKVEFFLRQ TFEDNLQVSE
560 570 580 590 600
VVSKCEVILV NNYLFDATLN SKVISLFQCL KESIGTKIVS LKPVIPLNYT
610 620 630 640 650
IHDDLTLTNV LSFMKTKRSV YSENSVSWTC KGGVYYLTEV VADVPIELMG
660
SSTRQSKSHN
Length:660
Mass (Da):75,308
Last modified:July 7, 2009 - v1
Checksum:iB2C155ECC3739187
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN392321 Genomic DNA. Translation: CAY71201.1.
RefSeqiXP_002493380.1. XM_002493335.1.

Genome annotation databases

EnsemblFungiiCAY71201; CAY71201; PAS_chr3_1133.
GeneIDi8200165.
KEGGippa:PAS_chr3_1133.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN392321 Genomic DNA. Translation: CAY71201.1 .
RefSeqi XP_002493380.1. XM_002493335.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 644223.PAS_chr3_1133.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CAY71201 ; CAY71201 ; PAS_chr3_1133 .
GeneIDi 8200165.
KEGGi ppa:PAS_chr3_1133.

Phylogenomic databases

eggNOGi NOG294902.
InParanoidi C4R367.
KOi K11427.
OrthoDBi EOG7KH9VN.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
InterProi IPR013110. DOT1.
IPR025789. Histone_H3-K79_MeTrfase.
IPR021162. Histone_H3-K79_MeTrfase_fungi.
IPR029063. SAM-dependent_MTases-like.
[Graphical view ]
Pfami PF08123. DOT1. 1 hit.
[Graphical view ]
PIRSFi PIRSF017570. Histone_H3-K79_MeTrfase. 1 hit.
SUPFAMi SSF53335. SSF53335. 1 hit.
PROSITEi PS51569. DOT1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GS115 / ATCC 20864Imported.

Entry informationi

Entry nameiC4R367_PICPG
AccessioniPrimary (citable) accession number: C4R367
Entry historyi
Integrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: October 29, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3