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C4R367

- C4R367_PICPG

UniProt

C4R367 - C4R367_PICPG

Protein
Submitted name:

Nucleosomal histone H3-Lys79 methylase, associates with transcriptionally active genes

Gene

PAS_chr3_1133

Organism
Komagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 34 (01 Oct 2014)
      Sequence version 1 (07 Jul 2009)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei504 – 5041S-adenosyl-L-methionineUniRule annotation

    GO - Molecular functioni

    1. histone-lysine N-methyltransferase activity Source: InterPro

    Keywords - Molecular functioni

    MethyltransferaseImported, Transferase

    Keywords - Ligandi

    S-adenosyl-L-methionineUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Nucleosomal histone H3-Lys79 methylase, associates with transcriptionally active genesImported
    Gene namesi
    Ordered Locus Names:PAS_chr3_1133Imported
    OrganismiKomagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)Imported
    Taxonomic identifieri644223 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKomagataella
    ProteomesiUP000000314: Chromosome 3

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: InterPro

    Interactioni

    Protein-protein interaction databases

    STRINGi644223.PAS_chr3_1133.

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni455 – 4584S-adenosyl-L-methionine bindingUniRule annotation
    Regioni478 – 48710S-adenosyl-L-methionine bindingUniRule annotation

    Phylogenomic databases

    eggNOGiNOG294902.
    KOiK11427.
    OrthoDBiEOG7KH9VN.

    Family and domain databases

    Gene3Di3.40.50.150. 1 hit.
    InterProiIPR013110. DOT1.
    IPR025789. Histone_H3-K79_MeTrfase.
    IPR021162. Histone_H3-K79_MeTrfase_fungi.
    IPR029063. SAM-dependent_MTases-like.
    [Graphical view]
    PfamiPF08123. DOT1. 1 hit.
    [Graphical view]
    PIRSFiPIRSF017570. Histone_H3-K79_MeTrfase. 1 hit.
    SUPFAMiSSF53335. SSF53335. 1 hit.
    PROSITEiPS51569. DOT1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C4R367-1 [UniParc]FASTAAdd to Basket

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    MGGTKIEDEN NACCLSKELD INPLWQTDET SRDELVQEAL LLESKSGSKP    50
    AHIAQLLDDS EWYRPSSFNE STVSPRPYNK SNHSAISTCK EGKSIETQGC 100
    QTNFKTAPSS TSCISKTKGA TKATKILTDK RSASPKALGM TREMKDLWAG 150
    AAWHLRDNPE YFSSKHQRKR LTQPNNRCNF HDSQTSQETH TGSKKAKKES 200
    ERPRKEQIKA KSKEVCLKIK NNELPQVETQ FESPDKQPTL EEPSKRFQNK 250
    IWFIEYDPHN ESQSVLVGNR KFFVDEIYEK QESPVTISNA KSAFALVNET 300
    KNRYWNDENL PPTAVYLSMP VSSYREKYQL IFPKDEELNP FEEIGRMMEI 350
    SALFYLPLKY ASLVRNEDSF ANCIVGQFIK AYERSHYEVI LKKIEEYNIL 400
    IDSLRSSGVI YDHIRAQTKV PRPMIYEILN QVYARTVSPN SKKLRQYKAF 450
    SNYVYGELLP NFLTQAFNEV KLDSSSKFID LGSGVGNCVF QAALEYGCES 500
    FGCEIMEHAS FLSELQLIEF KTRCDIFGIK PGKVEFFLRQ TFEDNLQVSE 550
    VVSKCEVILV NNYLFDATLN SKVISLFQCL KESIGTKIVS LKPVIPLNYT 600
    IHDDLTLTNV LSFMKTKRSV YSENSVSWTC KGGVYYLTEV VADVPIELMG 650
    SSTRQSKSHN 660
    Length:660
    Mass (Da):75,308
    Last modified:July 7, 2009 - v1
    Checksum:iB2C155ECC3739187
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN392321 Genomic DNA. Translation: CAY71201.1.
    RefSeqiXP_002493380.1. XM_002493335.1.

    Genome annotation databases

    EnsemblFungiiCAY71201; CAY71201; PAS_chr3_1133.
    GeneIDi8200165.
    KEGGippa:PAS_chr3_1133.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN392321 Genomic DNA. Translation: CAY71201.1 .
    RefSeqi XP_002493380.1. XM_002493335.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 644223.PAS_chr3_1133.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CAY71201 ; CAY71201 ; PAS_chr3_1133 .
    GeneIDi 8200165.
    KEGGi ppa:PAS_chr3_1133.

    Phylogenomic databases

    eggNOGi NOG294902.
    KOi K11427.
    OrthoDBi EOG7KH9VN.

    Family and domain databases

    Gene3Di 3.40.50.150. 1 hit.
    InterProi IPR013110. DOT1.
    IPR025789. Histone_H3-K79_MeTrfase.
    IPR021162. Histone_H3-K79_MeTrfase_fungi.
    IPR029063. SAM-dependent_MTases-like.
    [Graphical view ]
    Pfami PF08123. DOT1. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF017570. Histone_H3-K79_MeTrfase. 1 hit.
    SUPFAMi SSF53335. SSF53335. 1 hit.
    PROSITEi PS51569. DOT1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: GS115 / ATCC 20864Imported.

    Entry informationi

    Entry nameiC4R367_PICPG
    AccessioniPrimary (citable) accession number: C4R367
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 7, 2009
    Last sequence update: July 7, 2009
    Last modified: October 1, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3