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C4R236

- C4R236_PICPG

UniProt

C4R236 - C4R236_PICPG

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Protein

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2

Gene

PAS_chr2-2_0346

Organism
Komagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains.UniRule annotation

Catalytic activityi

Dolichyl diphosphooligosaccharide + [protein]-L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by N-beta-D-glycosyl linkage to a protein L-asparagine.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. dolichyl-diphosphooligosaccharide-protein glycotransferase activity Source: InterPro

GO - Biological processi

  1. protein glycosylation Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

TransferaseUniRule annotationImported

Enzyme and pathway databases

UniPathwayiUPA00378.

Names & Taxonomyi

Protein namesi
Recommended name:
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2UniRule annotation (EC:2.4.99.18UniRule annotation)
Short name:
Oligosaccharyl transferase subunit OST2UniRule annotation
Gene namesi
Ordered Locus Names:PAS_chr2-2_0346Imported
OrganismiKomagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)Imported
Taxonomic identifieri644223 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesPhaffomycetaceaeKomagataella
ProteomesiUP000000314: Chromosome 2

Subcellular locationi

Endoplasmic reticulum membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. oligosaccharyltransferase complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation, Membrane

Interactioni

Subunit structurei

Component of the oligosaccharyltransferase (OST) complex.UniRule annotation

Protein-protein interaction databases

STRINGi644223.PAS_chr2-2_0346.

Family & Domainsi

Sequence similaritiesi

Belongs to the DAD/OST2 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiNOG246737.
HOGENOMiHOG000211854.
InParanoidiC4R236.
KOiK12668.
OrthoDBiEOG757D9B.

Family and domain databases

InterProiIPR003038. DAD/Ost2.
[Graphical view]
PANTHERiPTHR10705. PTHR10705. 1 hit.
PfamiPF02109. DAD. 1 hit.
[Graphical view]
PIRSFiPIRSF005588. DAD. 1 hit.

Sequencei

Sequence statusi: Complete.

C4R236-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAKKHPTQQS ATVNPLSLTR SLPHELSEAI STSLASYQKS ISGNRKLRLI
60 70 80 90 100
DYFLTFLVFL GVLQFAFCLL VGTFPFNAFL GGFCSTVAQF VLTISLRLQT
110 120 130
TGTKEIFQNI SSQRAFAEYI FASLLLHFIV YHFIN
Length:135
Mass (Da):15,162
Last modified:July 7, 2009 - v1
Checksum:i39911E75D344E046
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN392320 Genomic DNA. Translation: CAY69560.1.
RefSeqiXP_002491840.1. XM_002491795.1.

Genome annotation databases

EnsemblFungiiCAY69560; CAY69560; PAS_chr2-2_0346.
GeneIDi8198246.
KEGGippa:PAS_chr2-2_0346.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN392320 Genomic DNA. Translation: CAY69560.1 .
RefSeqi XP_002491840.1. XM_002491795.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 644223.PAS_chr2-2_0346.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CAY69560 ; CAY69560 ; PAS_chr2-2_0346 .
GeneIDi 8198246.
KEGGi ppa:PAS_chr2-2_0346.

Phylogenomic databases

eggNOGi NOG246737.
HOGENOMi HOG000211854.
InParanoidi C4R236.
KOi K12668.
OrthoDBi EOG757D9B.

Enzyme and pathway databases

UniPathwayi UPA00378 .

Family and domain databases

InterProi IPR003038. DAD/Ost2.
[Graphical view ]
PANTHERi PTHR10705. PTHR10705. 1 hit.
Pfami PF02109. DAD. 1 hit.
[Graphical view ]
PIRSFi PIRSF005588. DAD. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GS115 / ATCC 20864Imported.

Entry informationi

Entry nameiC4R236_PICPG
AccessioniPrimary (citable) accession number: C4R236
Entry historyi
Integrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: October 29, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3