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C4R236

- C4R236_PICPG

UniProt

C4R236 - C4R236_PICPG

Protein

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2

Gene

PAS_chr2-2_0346

Organism
Komagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 29 (01 Oct 2014)
      Sequence version 1 (07 Jul 2009)
      Previous versions | rss
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    Functioni

    Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains.UniRule annotation

    Catalytic activityi

    Dolichyl diphosphooligosaccharide + [protein]-L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by N-beta-D-glycosyl linkage to a protein L-asparagine.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. dolichyl-diphosphooligosaccharide-protein glycotransferase activity Source: InterPro

    GO - Biological processi

    1. protein glycosylation Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    TransferaseUniRule annotationImported

    Enzyme and pathway databases

    UniPathwayiUPA00378.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2UniRule annotation (EC:2.4.99.18UniRule annotation)
    Short name:
    Oligosaccharyl transferase subunit OST2UniRule annotation
    Gene namesi
    Ordered Locus Names:PAS_chr2-2_0346Imported
    OrganismiKomagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)Imported
    Taxonomic identifieri644223 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeKomagataella
    ProteomesiUP000000314: Chromosome 2

    Subcellular locationi

    Endoplasmic reticulum membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. oligosaccharyltransferase complex Source: InterPro

    Keywords - Cellular componenti

    Endoplasmic reticulumUniRule annotation, Membrane

    Interactioni

    Subunit structurei

    Component of the oligosaccharyltransferase (OST) complex.UniRule annotation

    Protein-protein interaction databases

    STRINGi644223.PAS_chr2-2_0346.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the DAD/OST2 family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixUniRule annotation

    Phylogenomic databases

    eggNOGiNOG246737.
    HOGENOMiHOG000211854.
    KOiK12668.
    OrthoDBiEOG757D9B.

    Family and domain databases

    InterProiIPR003038. DAD/Ost2.
    [Graphical view]
    PANTHERiPTHR10705. PTHR10705. 1 hit.
    PfamiPF02109. DAD. 1 hit.
    [Graphical view]
    PIRSFiPIRSF005588. DAD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    C4R236-1 [UniParc]FASTAAdd to Basket

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    MAKKHPTQQS ATVNPLSLTR SLPHELSEAI STSLASYQKS ISGNRKLRLI    50
    DYFLTFLVFL GVLQFAFCLL VGTFPFNAFL GGFCSTVAQF VLTISLRLQT 100
    TGTKEIFQNI SSQRAFAEYI FASLLLHFIV YHFIN 135
    Length:135
    Mass (Da):15,162
    Last modified:July 7, 2009 - v1
    Checksum:i39911E75D344E046
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN392320 Genomic DNA. Translation: CAY69560.1.
    RefSeqiXP_002491840.1. XM_002491795.1.

    Genome annotation databases

    EnsemblFungiiCAY69560; CAY69560; PAS_chr2-2_0346.
    GeneIDi8198246.
    KEGGippa:PAS_chr2-2_0346.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FN392320 Genomic DNA. Translation: CAY69560.1 .
    RefSeqi XP_002491840.1. XM_002491795.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 644223.PAS_chr2-2_0346.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CAY69560 ; CAY69560 ; PAS_chr2-2_0346 .
    GeneIDi 8198246.
    KEGGi ppa:PAS_chr2-2_0346.

    Phylogenomic databases

    eggNOGi NOG246737.
    HOGENOMi HOG000211854.
    KOi K12668.
    OrthoDBi EOG757D9B.

    Enzyme and pathway databases

    UniPathwayi UPA00378 .

    Family and domain databases

    InterProi IPR003038. DAD/Ost2.
    [Graphical view ]
    PANTHERi PTHR10705. PTHR10705. 1 hit.
    Pfami PF02109. DAD. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF005588. DAD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: GS115 / ATCC 20864Imported.

    Entry informationi

    Entry nameiC4R236_PICPG
    AccessioniPrimary (citable) accession number: C4R236
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 7, 2009
    Last sequence update: July 7, 2009
    Last modified: October 1, 2014
    This is version 29 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3