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Protein
Submitted name:

Hexokinase isoenzyme 2 that catalyzes phosphorylation of glucose in the cytosol

Gene

PAS_chr1-4_0447

Organism
Komagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. kinase activity Source: UniProtKB-KW
  3. phosphotransferase activity, alcohol group as acceptor Source: InterPro

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotationImported, Transferase

Keywords - Biological processi

GlycolysisSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Hexokinase isoenzyme 2 that catalyzes phosphorylation of glucose in the cytosolImported
Gene namesi
Ordered Locus Names:PAS_chr1-4_0447Imported
OrganismiKomagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)Imported
Taxonomic identifieri644223 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesPhaffomycetaceaeKomagataella
ProteomesiUP000000314: Chromosome 1

Interactioni

Protein-protein interaction databases

STRINGi644223.PAS_chr1-4_0447.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG5026.
InParanoidiC4QYH5.
KOiK00844.
OrthoDBiEOG7NGQMP.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.

Sequencei

Sequence statusi: Complete.

C4QYH5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVPVLTPQFH SSPSVSDFTA FINRSNVVSI TSNLYESYKE AIHSSNVSMY
60 70 80 90 100
CTNSSTPTGN ECGTCLVVEL GGSTLRIAVL RLEKRKYENL YQRDWTLTES
110 120 130 140 150
DKVIDLKFFD EIAQKITNIP SLRSHFRNDT IRIGISWSFP LEQTSSSQAV
160 170 180 190 200
LQTMGKGFRL SESTHGQDLK TLFENSLKSN GIDASVESII NDSVAVFVAG
210 220 230 240 250
NYLESCVTGL VAGTGVNCAL VVDRKMIGLQ KSQEQIRPLR KGNFDKVVLN
260 270 280 290 300
SELGFFGGFL CQHSTIWDKM VHENWALHHS VQTNQPHMTL ALGCFQPIEM
310 320 330 340 350
MCSGRYIGEL TRLAILSLID SKQLFKGSRQ NIPSAFNVPY SLGGAIVSEI
360 370 380 390 400
YESEGHLPEL WAPLAPSQED YQILFKVVDS IIERASVVLG CAIIALLKLS
410 420 430 440 450
ESSATIDPTG SGSCRPYRIG YVGSVLKCFK PYREKVEMVL NLASKLQIIN
460 470
RPASLIYIDD SNLVGAAVSV FTPE
Length:474
Mass (Da):52,321
Last modified:July 7, 2009 - v1
Checksum:i9F8459EB7D6D80E1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN392319 Genomic DNA. Translation: CAY68298.1.
RefSeqiXP_002490579.1. XM_002490534.1.

Genome annotation databases

EnsemblFungiiCAY68298; CAY68298; PAS_chr1-4_0447.
GeneIDi8197035.
KEGGippa:PAS_chr1-4_0447.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN392319 Genomic DNA. Translation: CAY68298.1.
RefSeqiXP_002490579.1. XM_002490534.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi644223.PAS_chr1-4_0447.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAY68298; CAY68298; PAS_chr1-4_0447.
GeneIDi8197035.
KEGGippa:PAS_chr1-4_0447.

Phylogenomic databases

eggNOGiCOG5026.
InParanoidiC4QYH5.
KOiK00844.
OrthoDBiEOG7NGQMP.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GS115 / ATCC 20864Imported.

Entry informationi

Entry nameiC4QYH5_PICPG
AccessioniPrimary (citable) accession number: C4QYH5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: February 4, 2015
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.