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Protein

Histone-lysine N-methyltransferase

Gene

PAS_chr1-1_0102

Organism
Komagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

  1. histone-lysine N-methyltransferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferaseSAAS annotation (EC:2.1.1.43SAAS annotation)
Gene namesi
Ordered Locus Names:PAS_chr1-1_0102Imported
OrganismiKomagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)Imported
Taxonomic identifieri644223 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesPhaffomycetaceaeKomagataella
ProteomesiUP000000314 Componenti: Chromosome 1

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi644223.PAS_chr1-1_0102.

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains 1 post-SET domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG2940.
InParanoidiC4QW41.
KOiK06101.
OrthoDBiEOG7P8PH3.

Family and domain databases

InterProiIPR006560. AWS_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
[Graphical view]
PfamiPF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C4QW41-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLASQSEEEP FSFYMWCDMP SRPSRNSLKD STYLPLSELL EHGEAPTTRP
60 70 80 90 100
SRKLTRSIEQ CKKWVACIDH SNFPGHWSVG KRGCRTKVQL QMQLILSAAT
110 120 130 140 150
GSPLKLWIFS QRGLEVVSFL LIPKPEALQF VSPTRKQKRK IVSLPNSNFR
160 170 180 190 200
ATTAEWANLA KNIWRSSKEH DKVIKNSRSL RDYNSCNCRV NCGDLCLNRI
210 220 230 240 250
LQIECDSTIC KLSETRSCGN TQFTTLELGI SSLFREGTRV CRIDDKKGYG
260 270 280 290 300
LVAIREFAPY ELICEYTGEV INQEVVKERL SKKKVFHYYH LSLEQGLSID
310 320 330 340 350
STVKGSVARF VNHSCAPNAE VQKWYVQDEP RIGLFAGSKG IIPGDEITYD
360 370 380 390 400
YNFIWLENAE PQLCYCQSAN CRGVIGKKHS PSPVSQPTKS SKRTPQEGSQ
410 420 430 440 450
PSRKRGQHKI KDNQLLKTEK DTDARRLRRS IRHKGLAPDV GNTLQRLPLH
460 470 480 490 500
VRKQLSIDMA PPGKADDISR QLLAVLLPTE GRTRSSRQRK VVEACIKTGI
510 520 530 540 550
PLKYTGLDIK EPFPKKRVNK RNSARKLRSS SKSSSTSKKS ASETLILKEE
560 570 580
PKNHPPPPRV SEKLKIAHII HSSEESLSSI PFHPINQIN
Length:589
Mass (Da):66,686
Last modified:July 7, 2009 - v1
Checksum:iCDADA00A8F0AC059
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN392319 Genomic DNA. Translation: CAY67464.1.
RefSeqiXP_002489745.1. XM_002489700.1.

Genome annotation databases

EnsemblFungiiCAY67464; CAY67464; PAS_chr1-1_0102.
GeneIDi8197228.
KEGGippa:PAS_chr1-1_0102.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FN392319 Genomic DNA. Translation: CAY67464.1.
RefSeqiXP_002489745.1. XM_002489700.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi644223.PAS_chr1-1_0102.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAY67464; CAY67464; PAS_chr1-1_0102.
GeneIDi8197228.
KEGGippa:PAS_chr1-1_0102.

Phylogenomic databases

eggNOGiCOG2940.
InParanoidiC4QW41.
KOiK06101.
OrthoDBiEOG7P8PH3.

Family and domain databases

InterProiIPR006560. AWS_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
[Graphical view]
PfamiPF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GS115 / ATCC 20864Imported.

Entry informationi

Entry nameiC4QW41_PICPG
AccessioniPrimary (citable) accession number: C4QW41
Entry historyi
Integrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: April 29, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.