C4QVR2 (C4QVR2_PICPG) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
tRNA pseudouridine synthase RuleBase RU003792
EC=5.4.99.- RuleBase RU003792

Gene names

Ordered Locus Names:

PAS_chr1-3_0271

Organism

Komagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris) [Complete proteome]

Taxonomic identifier

644223 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Komagataella › Komagataella pastoris

Protein attributes

Sequence length	438 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	tRNA uridine = tRNA pseudouridine. RuleBase RU003792
Sequence similarities	Belongs to the tRNA pseudouridine synthase TruA family. RuleBase RU003792

Ontologies

Keywords
Biological process	tRNA processing RuleBase RU003792
Molecular function	Isomerase RuleBase RU003792
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	pseudouridine synthesis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	RNA binding Inferred from electronic annotation. Source: InterPro pseudouridine synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C4QVR2 [UniParc]. Last modified July 7, 2009. Version 1. Checksum: 491FA56DCE290AD5	FASTA	438	50,270
	10 20 30 40 50 60 MRPFPSLLKN HHLRLLMSDT DYRKWSKPQL ISRILQLEGK SGELALMESK PRKNEVDFST 70 80 90 100 110 120 ATIRQIALKF SYLGWNYQGL AVQREATDLP TIEFKILEAL RQCRMIPSLN PIDCAFSRCG 130 140 150 160 170 180 RTDKGVSAMN QVIGLNVRSR LTPEELESPE NDIKELDYIN ILNQLLPSDI RIHGVCLRPP 190 200 210 220 230 240 KGFDARFSCR GRHYKYVFQD EGLDLESMKK AAPMFEGVHD FRNFCKVDGA KQMTNYTRAV 250 260 270 280 290 300 RSSQILPLEG HPGYYVFDLK GTAFLWHQVR CMVAILLMIG QGFESPDIVS KLLDIQSHPQ 310 320 330 340 350 360 KPVYVMAHDI PLVLYDCIYD DDVNFQPATN ANKILKSHQE FRGVYYDYHL KYIISNFMRN 370 380 390 400 410 420 IVMPGPIQIT AGKQLHNTGD GKGKFANKHV KLLNRPTVEE PEVLNEKWRK KRKLIAEQES 430 KEELQETNGI SNGDVPSI

References

[1]

"Genome sequence of the recombinant protein production host Pichia pastoris." De Schutter K., Lin Y.-C., Tiels P., Van Hecke A., Glinka S., Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N. Nat. Biotechnol. 27:561-566(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GS115 / ATCC 20864.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FN392319 Genomic DNA. Translation: CAY67335.1.
RefSeq	XP_002489616.1. XM_002489571.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	644223.PAS_chr1-3_0271.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	CAY67335; CAY67335; PAS_chr1-3_0271.
GeneID	8196839.
KEGG	ppa:PAS_chr1-3_0271.
Phylogenomic databases
eggNOG	COG0101.
HOGENOM	HOG000199032.
KO	K01855.
OrthoDB	EOG46T69C.
Family and domain databases
Gene3D	3.30.70.580. 1 hit. 3.30.70.660. 1 hit.
HAMAP	MF_00171. TruA.
InterPro	IPR020103. PsdUridine_synth_cat_dom. IPR001406. PsdUridine_synth_TruA. IPR020097. PsdUridine_synth_TruA_a/b_dom. IPR020095. PsdUridine_synth_TruA_C. IPR020094. PsdUridine_synth_TruA_N. [Graphical view]
PANTHER	PTHR11142. PTHR11142. 1 hit.
Pfam	PF01416. PseudoU_synth_1. 2 hits. [Graphical view]
SUPFAM	SSF55120. PsdUridine_synth_cat_dom. 1 hit.
TIGRFAMs	TIGR00071. hisT_truA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C4QVR2_PICPG

Accession

Primary (citable) accession number: C4QVR2

Entry history

Integrated into UniProtKB/TrEMBL:	July 7, 2009
Last sequence update:	July 7, 2009
Last modified:	May 1, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)