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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

Smp_030500.1

Organism
Schistosoma mansoni (Blood fluke)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei41NADUniRule annotation1
Binding sitei97NADUniRule annotation1
Binding sitei120SubstrateUniRule annotation1
Binding sitei154NAD; via amide nitrogenUniRule annotation1
Active sitei205Proton acceptorUniRule annotation1
Binding sitei271NADUniRule annotation1
Binding sitei300NADUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 15NADUniRule annotation6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationImported
LigandNADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
ORF Names:Smp_030500.1Imported
OrganismiSchistosoma mansoni (Blood fluke)Imported
Taxonomic identifieri6183 [NCBI]
Taxonomic lineageiEukaryotaMetazoaPlatyhelminthesTrematodaDigeneaStrigeididaSchistosomatoideaSchistosomatidaeSchistosoma
Proteomesi
  • UP000008854 Componenti: Unassembled WGS sequence

Subcellular locationi

Expressioni

Gene expression databases

ExpressionAtlasiC4Q5J8 baseline

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi6183.Smp_030500.1__mRNA

Structurei

3D structure databases

ProteinModelPortaliC4Q5J8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 173NAD_Gly3P_dh_NInterPro annotationAdd BLAST168
Domaini194 – 341NAD_Gly3P_dh_CInterPro annotationAdd BLAST148

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni271 – 272Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2711 Eukaryota
COG0240 LUCA
HOGENOMiHOG000246855
InParanoidiC4Q5J8
KOiK00006
OMAiWLCKGFE
OrthoDBiEOG091G0DO6
PhylomeDBiC4Q5J8

Family and domain databases

Gene3Di1.10.1040.10, 1 hit
InterProiView protein in InterPro
IPR008927 6-PGluconate_DH-like_C_sf
IPR013328 6PGD_dom2
IPR006168 G3P_DH_NAD-dep
IPR006109 G3P_DH_NAD-dep_C
IPR017751 G3P_DH_NAD-dep_euk
IPR011128 G3P_DH_NAD-dep_N
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF07479 NAD_Gly3P_dh_C, 1 hit
PF01210 NAD_Gly3P_dh_N, 1 hit
PIRSFiPIRSF000114 Glycerol-3-P_dh, 1 hit
PRINTSiPR00077 GPDHDRGNASE
SUPFAMiSSF48179 SSF48179, 1 hit
SSF51735 SSF51735, 1 hit
TIGRFAMsiTIGR03376 glycerol3P_DH, 1 hit
PROSITEiView protein in PROSITE
PS00957 NAD_G3PDH, 1 hit

Sequencei

Sequence statusi: Complete.

C4Q5J8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLRRVSVIG SGNWGSTIAK IVGNNIKKFP EYVPEVRMWV FEELVNGRKL
60 70 80 90 100
TEIINTSHEN VKYLPNVKLP ENVVADPDVK SVARDADVLI IVMPHQFLNR
110 120 130 140 150
TLAEMKPVVK PTSYAISLMK GLALSDDHGI KLLTDCIRDV LSIPCAVLMG
160 170 180 190 200
ANLATEVSQE NYCEATIGID NPKMGSELKK LFQTDYFRIV VIKDEVATEL
210 220 230 240 250
CGALKNIVAV AAGVIEGLGY GDNTKAAVIR LGFMEMKSFI YQFFADRHPQ
260 270 280 290 300
EGTFLESCGV ADLITTCYGG RNKQMGIALA TTNEPLAQLE KERLHGQSAQ
310 320 330 340 350
GPLTAAEVYA MLERKGLLEK YPIFTAVHKL CTRQFDPKNF ICCLANHPEH

R
Length:351
Mass (Da):38,861
Last modified:July 7, 2009 - v1
Checksum:i89E97E9CF48A253B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CABG01000123 Genomic DNA Translation: CAZ30729.1
RefSeqiXP_018644200.1, XM_018792589.1

Genome annotation databases

EnsemblMetazoaiSmp_030500.1; Smp_030500.1:pep; Smp_030500
GeneDBiSmp_030500.1:pep
GeneIDi8349719
KEGGismm:Smp_030500.1

Similar proteinsi

Entry informationi

Entry nameiC4Q5J8_SCHMA
AccessioniPrimary (citable) accession number: C4Q5J8
Entry historyiIntegrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: May 23, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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