Skip Header

Contribute Send feedback
Read comments (?) or add your own

C4PPR7 (C4PPR7_CHLTJ) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase HAMAP MF_00387
Short name=UDP-N-acetylglucosamine acyltransferase HAMAP MF_00387
EC=2.3.1.129 HAMAP MF_00387
Gene names
Name:lpxA HAMAP MF_00387 EMBL CAX10988.1
Ordered Locus Names:JALI_5341
OrganismChlamydia trachomatis serovar B (strain Jali20/OT) [Complete proteome] [HAMAP]
Taxonomic identifier580049 [NCBI]
Taxonomic lineageBacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia

Protein attributes

Sequence length280 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. HAMAP MF_00387 SAAS SAAS010137

Catalytic activity

(R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-N-acetylglucosamine = [acyl-carrier-protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine. HAMAP MF_00387 SAAS SAAS010137

Pathway

Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6. HAMAP MF_00387 SAAS SAAS010137

Subunit structure

Homotrimer By similarity. HAMAP MF_00387 SAAS SAAS010137

Subcellular location

Cytoplasm By similarity HAMAP MF_00387.

Sequence similarities

Belongs to the transferase hexapeptide repeat family. LpxA subfamily. HAMAP MF_00387

Sequences

Sequence LengthMass (Da)Tools
C4PPR7 [UniParc].

Last modified November 3, 2009. Version 1.
Checksum: 3628079AC336BF34

FASTA28030,751
        10         20         30         40         50         60 
MTNIHPTAIV EDGARIGNNV TIEPYAIVKK NVTLCDDVVV KSYAYIDGFT TIGRGTTVWP 

        70         80         90        100        110        120 
SAMIGNKPQD LKFKGEKTFV EIGEHCEIRE FAMITSSTFE GTTVSIGNNC LIMPWAHIAH 

       130        140        150        160        170        180 
NCSVGNNVVF STHVQLAGHV QVGDCVTIGS MVGVHQFVRI GSYSMVGAMS GIRRDIPPFT 

       190        200        210        220        230        240 
IGTGNPYALG GINKVGLQRR QVSFETRLAL IKTFKRVFRS DESFQASLES VLEDFGEVPE 

       250        260        270        280 
VRHFVEFCRQ PSKRGIERGV DCEASLEEPI DKKEGAFVES

« Hide

References

[1]"Co-evolution of genomes and plasmids within Chlamydia trachomatis and the emergence in Sweden of a new variant strain."
Seth-Smith H.M.B., Harris S.R., Persson K., Marsh P., Barron A., Bignell A., Bjartling C., Clark L., Cutcliffe L.T., Lambden P.R., Lennard N., Lockey S.J., Quail M.A., Salim O., Skilton R.J., Wang Y., Holland M.J., Parkhill J., Thomson N.R., Clarke I.N.
BMC Genomics 10:239-239(2009) [PubMed: 19460133] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FM872308 Genomic DNA. Translation: CAX10988.1.
RefSeqYP_002888154.1. NC_012686.1.

3D structure databases

ProteinModelPortalC4PPR7.
ModBaseSearch...

Protein-protein interaction databases

STRINGC4PPR7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7881935.
GenomeReviewsGene locus JALI_5341 in contig FM872308_GR.
KEGGctj:JALI_5341.
PATRIC20378660. VBIChlTra100303_0598.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAGDKNLLM.
ProtClustDBPRK05289.

Family and domain databases

HAMAPMF_00387. LpxA.
[Tree]
InterProIPR001451. Hexapep_transf.
IPR018357. Hexapep_transf_CS.
IPR010137. Lipid_A_lpxA.
IPR011004. Trimer_LpxA-like.
[Graphical view]
KOK00677.
PfamPF00132. Hexapep. 5 hits.
[Graphical view]
PIRSFPIRSF000456. UDP-GlcNAc_acltr. 1 hit.
SUPFAMSSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMsTIGR01852. Lipid_A_lpxA. 1 hit.
PROSITEPS00101. HEXAPEP_TRANSFERASES. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC4PPR7_CHLTJ
AccessionPrimary (citable) accession number: C4PPR7
Entry history
Integrated into UniProtKB/TrEMBL: November 3, 2009
Last sequence update: November 3, 2009
Last modified: January 25, 2012
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info