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Protein
Submitted name:

Extracellular transglutaminase

Gene

eTG

Organism
Strongylocentrotus purpuratus (Purple sea urchin)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei325 – 3251UniRule annotation
Active sitei384 – 3841UniRule annotation
Active sitei407 – 4071UniRule annotation

GO - Molecular functioni

  1. protein-glutamine gamma-glutamyltransferase activity Source: InterPro

GO - Biological processi

  1. peptide cross-linking Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Extracellular transglutaminaseImported
Gene namesi
Name:eTGImported
OrganismiStrongylocentrotus purpuratus (Purple sea urchin)Imported
Taxonomic identifieri7668 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEchinodermataEleutherozoaEchinozoaEchinoideaEuechinoideaEchinaceaEchinoidaStrongylocentrotidaeStrongylocentrotus

Interactioni

Protein-protein interaction databases

STRINGi7668.C4P258.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG80379.
KOiK05619.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Complete.

C4P258-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVRRSTRTSR TPSRFGYSAR YEPYTVRKAS VLVPAAGRRN VPTQPLVIEK
60 70 80 90 100
AKETVKQLKV TAVDLCSEAN KKAHHTDAYE VDQLILRRGQ VMDMCVTFDR
110 120 130 140 150
AYSSAKDTLS LELLMGSRPS VASGSRVPID LVTRAPPPDD FGLQVVSSSG
160 170 180 190 200
NKVTMKVHLA CDALVGEYQL VVCTAQTKEE DEYRYECEDD IIILFNPWCK
210 220 230 240 250
KDDVYMENDK WRKEYVMNEN GAYFYGTASN IGSSAWYQGQ FEEVALECAL
260 270 280 290 300
YLLKKSRMTS RHRSSPVEIC RVLSALVNSQ DDDGVLVGNW SGDYSDGVEP
310 320 330 340 350
TAWNGSISIL SQYMKTETPV EYGQCWVFGS LLTTLCRTLG IPCRTITNFE
360 370 380 390 400
SAHDSDANLT LDYHFNEEGD PLEDLNDDSI WNFHVWNDVW FARPDLPEGY
410 420 430 440 450
GGWQALDSTP QETSHGEFRM GPASLKAIKQ GHVYLDYDTK FAFSEVNAET
460 470 480 490 500
VYWTVPKNAR HAPQVITTDP KGVGNHISTK AVLAESRQDI TEEYKYKEGS
510 520 530 540 550
SLERIAVYNA SRYVAKNKNF RKDIKQDVEF EVVLADGTMI GKDFSVKVIA
560 570 580 590 600
TNKSSTTRSG SVTLTGSTVF YTGVRKTRVY SSRRTFSMRA GESETETFTV
610 620 630 640 650
EAADYIPELT EYAGFTFFIM SSVTQTKQVF SIQKDFVLNK PTLELSITED
660 670 680 690 700
LMVGQPMRLS VTFTNPLDKA IRNGVFRIEG PDIDGFKADK FRVIQPNEKV
710 720 730 740
THVVRIVPKR TGNRRFFANF SSDILIALKG SSTFVVGPSA
Length:740
Mass (Da):83,089
Last modified:July 7, 2009 - v1
Checksum:i9FF956B41DF6B1BB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ829470 mRNA. Translation: ACQ66511.1.
RefSeqiNP_001154909.1. NM_001161437.2.
UniGeneiSpu.26495.

Genome annotation databases

GeneIDi578380.
KEGGispu:578380.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ829470 mRNA. Translation: ACQ66511.1.
RefSeqiNP_001154909.1. NM_001161437.2.
UniGeneiSpu.26495.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7668.C4P258.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi578380.
KEGGispu:578380.

Organism-specific databases

CTDi578380.

Phylogenomic databases

eggNOGiNOG80379.
KOiK05619.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Extracellular matrix modifications at fertilization: regulation of dityrosine crosslinking by transamidation."
    Wong J.L., Wessel G.M.
    Development 0:0-0(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiC4P258_STRPU
AccessioniPrimary (citable) accession number: C4P258
Entry historyi
Integrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: October 1, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.